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Signal transduction in inflammatory cells. Part A /
Cellular and Molecular Mechanisms of Inflammation.
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, California :
London [England],
1992.
|
| Colección: | Cellular and molecular mechanisms of inflammation ;
Volume 3. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover image; Title page; Table of Contents; Copyright; Preface; Chapter 1: Real-Time Analysis of Ligand-Receptor Dynamics and Binding Pocket Structure of the Formyl Peptide Receptor; Publisher Summary; Introduction; Birth of Real-Time Assays for Neutrophil Receptor Dynamics; Early Methods 1980-1985; Receptor-G Protein Interactions; Intact Cell; Amplification; Ligand-Receptor Dynamics for Unlabeled Ligands; Receptor Binding Pocket Topography; Prospects for Generalizing Real-Time Methods for Kinetic and Structural Analyses; Acknowledgments
- Chapter 2: Structure and Function of GTP-Binding Proteins in Neutrophil Signal TransductionPublisher Summary; Introduction; Oligomeric G Proteins; Neutrophil G Proteins; Low-Molecular-Weight G Proteins; LMWGs in Neutrophils; G Protein Regulation of Oxidant Production in Neutrophils; Summary and Conclusions; Acknowledgments; Chapter 3: Regulation of Phospholipase C Isozymes; Publisher Summary; Activation of PLC by G Protein-Dependent and -Independent Pathways; Heterogeneity in the PI Response to Specific Ligands; Multiple Forms of PLC; G Protein-Dependent Activation of PLC
- Ca2+ Signal: Studies in Cell Populations and Single NeutrophilsNeutrophil Plasma Membrane: Ion Channels, Membrane Potential, and Ca2+ Influx; Intracellular Ca2+ Stores in Myeloid Cells; Phosphatidylinositol Turnover; Role of [Ca2+]i in the Regulation of Neutrophil Functions; Concluding Remarks; Acknowledgment; Chapter 6: Inositol Phosphate Metabolism; Publisher Summary; Introduction to Phosphatidylinositol Turnover; Discovering the Biological Role of Inositol Phosphates; Interconversion of the Phosphatidylinositols; PtdIns 3-kinase; Production of Inositol Phosphates; PtdIns-Specific PLC
- Cyclic Inositol Phosphate PathwayCyclic Hydrolase; Ins(1,4,5)P3/Ins(1,3,4,5)P4 Pathway; Possible Functions of Ins(1,3,4,5)P4; Ins(1,4,5)P3 3-kinase; Inositol Polyphosphate 5-phosphatase; Other Pathways of Inositol Phosphate Metabolism; Inositol Polyphosphate 1-phosphatase; Inositol Polyphosphate 4-phosphatase; Inositol Polyphosphate 3-phosphatase; Phosphorylation of Ins(1,3,4)P3; Monophosphatase; Closing Comments; Acknowledgments; Chapter 7: Phosphatidylinositol 3-kinase: A Novel Signal Transduction Pathway?; Publisher Summary; Introduction