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Hormonal steroids : proceedings of the Sixth International Congress on Hormonal Steroids, Jerusalem, Israel, 5-10 September 1982 /

Introduction; references; chapter 6. antiestrogen pharmacology and mechanism of action; summary; introduction; experimental section; results; discussion; references; chapter 7. cellular and molecular mechanism of action of antiestrogens; summary; introduction; 1. a tamoxifen metabolite with high aff...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: International Congress on Hormonal Steroids Jerusalem
Otros Autores: James, V. H. T. (Vivian Hector Thomas) (Editor ), Pasqualini, Jorge R. (Editor )
Formato: Electrónico Congresos, conferencias eBook
Idioma:Inglés
Publicado: Oxford, England ; Elmsford, New York : Pergamon Press, 1983.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Hormonal Steroids; Copyright Page; Table of Contents; International Organizing Committee; Programme Committee; Local Organizing Committee; SECTION 1: Plenary Lectures; CHAPTER 1. STEROID-PROTEIN INTERACTION: FROM PAST TO PRESENT; SUMMARY; INTRODUCTION; GENERAL PROPERTIES OF STEROID-BINDING PROTEINS; CORTICOSTEROID-BINDING GLOBULIN(CBG) OR TRANSCORTIN; INFLUENCE OF pH; KINETICS OF STEROID-PROTEIN INTERACTION; CHARACTERISTICS OF THE STEROID BINDING SITE; REFERENCES; CHAPTER 2. HORMONAL INTERACTIONS IN THE CONTROL OF GRANULOSA CELL DIFFERENTIATION; SUMMARY; INTRODUCTION.
  • Protein changes which occur as granulosa cells differentiate in follicles from the preantral to the antral stagehormones which interfere with the normal process of granulosa cell differentiation; references; chapter 3. enzyme induction by estrogen; summary; receptor-chromatin interactions: towards a cell-free system responsive to steroid hormones; quantitation of the ""estrogen-induced protein"" (ip) by radiolabeling of newly synthesized protein; identification of ip as the brain type (bb) isozyme of creatine kinase; range of induction of ckbb by estrogen.
  • CREATINE KINASE ISOZYMES AND MAMMARY TUMORSINCREASE IN TRANSLATABLE mRNA FORCKBB AFTER ESTROGEN TREATMENT; THE PROVISION OF A cDNA PROBE FOR THE CKBB GENE; CONCLUDING REMARKS; REFERENCES; CHAPTER 4. THE HORMONAL AND CELLULAR CONTROL OF SERTOLI CELL SECRETION; SUMMARY; INTRODUCTION; THE SECRETORY PRODUCTS OF SERTOLI CELLS; THE HUMORAL CONTROL OF PROTEIN SECRETION BY ISOLATED SERTOLI CELLS; THE CELLULAR CONTROL OF SERTOLI CELLS; SERTOLI PRODUCTS AS MARKERS OF TESTICULAR FUNCTION IN VIVO; REFERENCES; SECTION 2: Symposia; CHAPTER 5. AROMATASE INHIBITORS, THEIR PHARMACOLOGY AND APPLICATION.
  • 4. mechanism of the antiestrogen resistance in re positive cellsconclusions; references; chapter 8. guide-lines in the design of new antiestrogens and cytotoxic-linked estrogens for the treatment of breast cancer; summary; introduction; models for evaluating the potential therapeutic activity of the drugs; antiestrogens; cytotoxic estrogens; conclusions; references; chapter 9. immunoreactivity of the core of estrogen receptors found in different subcellular compartments of target cells from a variety of mammalian species; summary; introduction; materials and methods; results; references.