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Immunobiology of the complement system : an introduction for research and clinical medicine /
Immunobiology of the Complement System: An Introduction for Research and Clinical Medicine provides an introduction to the complement system. The intention was to create a primer that would provide the basic knowledge of complement required for either research or clinical medicine in diseases involv...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Orlando :
Academic Press,
[1986]
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Immunobiology of the Complement System: An Introduction for Research and Clinical Medicine; Copyright Page; Table of Contents; Preface; Introduction and History of Complement Research; I. THE COMPLEMENT SYSTEM; II. HISTORY OF RESEARCH ON COMPLEMENT; III. ROLE OF COMPLEMENT IN INFECTIONS ANDAUTOIMMUNE DISEASE; REFERENCES OF HISTORICAL INTEREST; Chapter 1. The Classical Pathway; I. INTRODUCTION; II. ACTIVATION CASCADE; III. REGULATORY FACTORS; IV. SUMMARY OF AMPLIFICATION FACTORS; REFERENCES; Chapter 2. The Alternative Pathway; I. INTRODUCTION; II. THE PROTEINS.
- III. THE ACTIVATION PROCESSIV. REGULATION OF ALTERNATIVE PATHWAYACTIVATION BY MEMBRANE-ASSOCIATED PROTEINS; V. BIOLOGICAL EFFECTS OF ALTERNATIVEPATHWAY ACTIVATION; REFERENCES; Chapter 3. Complement Mediatorsof Inflammation; I. INTRODUCTION; II. PRODUCTION OF THE ANAPHYLATOXINS; III. CONTROL MECHANISMS; IV. PHYSIOCHEMICAL CHARACTERIZATION OF THEHUMAN ANAPHYLATOXINS; V. BIOLOGICAL ACTIVITIES OF THE ANAPHYLATOX�INS; VI. THE C5a RECEPTOR; VII. SUMMARY; REFERENCES; Chapter 4. Opsonization and MembraneComplement Receptors; I. INTRODUCTION; II. OPSONIZATION; III. MEMBRANE COMPLEMENT RECEPTORS.
- IV. METHODS FOR DIRECTION OF OPSONIC COMPLEMENT FRAGMENTS AND COMPLEMENTRECEPTORSREFERENCES; Chapter 5. Assembly and Functions of the Terminal Components; I. INTRODUCTION; II. ASSEMBLY OF THE MAC; III. FUNCTIONAL EFFECTS OF THE MACON TARGET MEMBRANES; IV. ESCAPE MECHANISMS FROM MAC ATTACK; V. PATHOPHYSIOLOGICAL SIGNIFICANCE OF THEMEMBRANE ATTACK SEQUENCE; VI. PROTECTION OF HOST CELLS FROM ATTACKBY MAC; VII. PERSPECTIVES; ACKNOWLEDGMENTS; REFERENCES; Chapter 6.Complement-Dependent Mechanisms of Virus Neutralization; I. INTRODUCTION; II. IMMUNITY TO VIRUSES AND VIRUS-INFECTED CELLS.
- III. COMPLEMENT ACTIVATION BY VIRUSES ANDVIRUS-INFECTED CELLSIV. ANTIBODY- AND COMPLEMENT-DEPENDENT VIRALNEUTRALIZATION; V. EFFECTS OF ANTIBODY AND COMPLEMENT ONVIRUS-INFECTED CELLS; VI. CONCLUSIONS; REFERENCES; Chapter 7. Genetics and Synthesis of Components of the ComplementSystem; I. INTRODUCTION; II. GENETIC VARIANTS: POLYMORPHISM OF THECOMPLEMENT PROTEINS; III. STRUCTURE AND ORGANIZATION OFCOMPLEMENT GENES; IV. EXPRESSION OF COMPLEMENT GENES; V. COMPLEMENT DEFICIENCIES; VI. CONCLUSIONS; REFERENCES; Chapter 8. Role of Complement inInfectious Diseases; I. INTRODUCTION.
- II. MICROBIAL ANTIGENS CAPABLEOF ACTIVATING COMPLEMENTIII. LOCALIZATION OF ANTIBODY AND COMPLEMENTCOMPONENTS ON MICROORGANISMS; IV. COMPLEMENT-MEDIATED LYSIS OF BACTERIA; V. ROLE OF ANTIBODY AND COMPLEMENT IN BLOODSTREAMCLEARANCE OF MICROORGANISMS; VI. NONCOMPLEMENT AND NONANTIBODY FACTORSINTERACTING WITH COMPLEMENT IN HOST DEFENSE; VII. ROLE OF COMPLEMENT IN THE PATHOGENESISOF INFECTIOUS DISEASE; VIII. CONCLUSIONS; REFERENCES; Chapter 9. Complement and the Rheumatic Diseases; I. INTRODUCTION; II. SYSTEMIC LUPUS ERYTHEMATOSUS; III. RHEUMATOID ARTHRITIS ANDRELATED ARTHRITIDES; IV. CRYOGLOBULINS.