Cardiac regeneration and repair. Vol. 1, Pathology and Therapies /
Annotation
Clasificación: | Libro Electrónico |
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Otros Autores: | , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Cambridge :
Woodhead Publishing,
�2014.
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Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; Cardiac regeneration and repair: Volume 1: Pathology and therapies; Copyright; Contents; Contributor contact details; Woodhead Publishing Series in Biomaterials; Foreword; Introduction; Part I The pathogenesis of congestive heart failure; 1 Cardiac matrix remodeling and heart failure; 1.1 Introduction; 1.2 Cardiac matrix remodeling in the development and progression of heart failure (HF) after myocardial infarction (MI); 1.3 Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in matrix and cardiac remodeling
- 1.4 Role of infl ammation in matrix and cardiac remodeling1.5 Role of monocytes and macrophages in matrix and cardiac remodeling; 1.6 Extracellular matrix (ECM) and collagen deposition; 1.7 Treatment strategies and considerations; 1.8 Future trends; 1.9 Acknowledgments; 1.10 References; 2 Cardiac biomechanics and heart dysfunction; 2.1 Introduction; 2.2 Measures of cardiac biomechanics; 2.3 Techniques for assessing the parameters used to quantify cardiac function; 2.4 Passive versus active cardiac function; 2.5 Effects of ischemia and infarction on cardiac biomechanics; 2.6 Conclusion
- 2.7 References3 Modifying matrix remodeling to prevent heart failure; 3.1 Introduction; 3.2 Clinical progress and remaining issues; 3.3 Extracellular matrix (ECM) remodeling in the postmyocardial infarction setting; 3.4 Cells that modify ECM remodeling; 3.5 Therapeutic options; 3.6 Future trends; 3.7 Conclusion; 3.8 Sources of further information and advice; 3.9 Acknowledgements; 3.10 References; Part II Cell therapy for cardiac regeneration and repair; 4 Optimal cells for cardiac repair and regeneration; 4.1 Introduction; 4.2 Cell candidates for the repair of ischemic myocardium
- 4.3 Mechanisms of stem cell transplantation for myocardium repair4.4 Overview of the centers for cardiac cell transplantation; 4.5 Conclusion and future trends; 4.6 References; 4.7 Appendix: abbreviations and acronyms; 5 Cell delivery routes for cardiac stem cell therapy; 5.1 Introduction; 5.2 Intravenous (IV) injection for cell therapy to the heart; 5.3 Intramyocardial (IM) injection for cell therapy to the heart; 5.4 Intracoronary (IC) injection for cell therapy to the heart; 5.5 Advanced methods for cell therapy to the heart: tissue engineering and the cellsheet technique
- 5.6 Conclusion and future trends5.7 Acknowledgment; 5.8 References; 6 Cell therapy to regenerate the ischemic heart; 6.1 Introduction; 6.2 Pathology of ischemic damage; 6.3 Goals and mechanisms of cell therapy to regenerate the ischemic heart; 6.4 Candidate populations for cell therapy; 6.5 Variables of cell therapy; 6.6 Conclusion; 6.7 References; 7 Cell therapy for cardiac repair
- bench to bedside and back; 7.1 Introduction; 7.2 Transition of stem cell therapeutics from the bench to the clinic; 7.3 Skeletal myoblasts; 7.4 Hematological stem cell (HSC) products; 7.5 Conclusion