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140228s2014 enk o 001 0 eng d |
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|a UAB
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|a 871190296
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|a 1306459966
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|a 9781306459969
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|a 9780857096708
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|a 0857096702
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|z 9780857096586
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|a (OCoLC)876428783
|z (OCoLC)871190296
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|a QP114.R45
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|a HEA
|x 039000
|2 bisacsh
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|a MED
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|a 616.1/2
|2 23
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|a Cardiac regeneration and repair.
|n Vol. 1,
|p Pathology and Therapies /
|c edited by Ren-Ke Li and Richard D. Weisel.
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|a Pathology and therapies
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|a Cambridge :
|b Woodhead Publishing,
|c �2014.
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|a 1 online resource
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|a text
|b txt
|2 rdacontent
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|a computer
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|2 rdamedia
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|a online resource
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|a Print version record.
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|a Includes index.
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|a Annotation
|b Heart disease is the leading cause of death in the UK and the United States. For those who survive heart disease, few victims recover completely. Cell therapies, tissue engineering, and biomaterials technologies have advanced and now offer the potential to reverse the damage caused by heart disease. Volume 1 of this important set provides comprehensive information on the pathology of heart disease and the cell therapies available. Opening chapters look at cardiac pathology and current therapies. Further chapters present gene and protein therapies for regeneration, cell therapies for cardiac regeneration, and clinical considerations of stem cell therapies.
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|a Cover; Cardiac regeneration and repair: Volume 1: Pathology and therapies; Copyright; Contents; Contributor contact details; Woodhead Publishing Series in Biomaterials; Foreword; Introduction; Part I The pathogenesis of congestive heart failure; 1 Cardiac matrix remodeling and heart failure; 1.1 Introduction; 1.2 Cardiac matrix remodeling in the development and progression of heart failure (HF) after myocardial infarction (MI); 1.3 Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in matrix and cardiac remodeling
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|a 1.4 Role of infl ammation in matrix and cardiac remodeling1.5 Role of monocytes and macrophages in matrix and cardiac remodeling; 1.6 Extracellular matrix (ECM) and collagen deposition; 1.7 Treatment strategies and considerations; 1.8 Future trends; 1.9 Acknowledgments; 1.10 References; 2 Cardiac biomechanics and heart dysfunction; 2.1 Introduction; 2.2 Measures of cardiac biomechanics; 2.3 Techniques for assessing the parameters used to quantify cardiac function; 2.4 Passive versus active cardiac function; 2.5 Effects of ischemia and infarction on cardiac biomechanics; 2.6 Conclusion
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|a 2.7 References3 Modifying matrix remodeling to prevent heart failure; 3.1 Introduction; 3.2 Clinical progress and remaining issues; 3.3 Extracellular matrix (ECM) remodeling in the postmyocardial infarction setting; 3.4 Cells that modify ECM remodeling; 3.5 Therapeutic options; 3.6 Future trends; 3.7 Conclusion; 3.8 Sources of further information and advice; 3.9 Acknowledgements; 3.10 References; Part II Cell therapy for cardiac regeneration and repair; 4 Optimal cells for cardiac repair and regeneration; 4.1 Introduction; 4.2 Cell candidates for the repair of ischemic myocardium
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|a 4.3 Mechanisms of stem cell transplantation for myocardium repair4.4 Overview of the centers for cardiac cell transplantation; 4.5 Conclusion and future trends; 4.6 References; 4.7 Appendix: abbreviations and acronyms; 5 Cell delivery routes for cardiac stem cell therapy; 5.1 Introduction; 5.2 Intravenous (IV) injection for cell therapy to the heart; 5.3 Intramyocardial (IM) injection for cell therapy to the heart; 5.4 Intracoronary (IC) injection for cell therapy to the heart; 5.5 Advanced methods for cell therapy to the heart: tissue engineering and the cellsheet technique
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|a 5.6 Conclusion and future trends5.7 Acknowledgment; 5.8 References; 6 Cell therapy to regenerate the ischemic heart; 6.1 Introduction; 6.2 Pathology of ischemic damage; 6.3 Goals and mechanisms of cell therapy to regenerate the ischemic heart; 6.4 Candidate populations for cell therapy; 6.5 Variables of cell therapy; 6.6 Conclusion; 6.7 References; 7 Cell therapy for cardiac repair -- bench to bedside and back; 7.1 Introduction; 7.2 Transition of stem cell therapeutics from the bench to the clinic; 7.3 Skeletal myoblasts; 7.4 Hematological stem cell (HSC) products; 7.5 Conclusion
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|a Myocardium
|x Regeneration.
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|a Myocarde
|x R�eg�en�eration.
|0 (CaQQLa)201-0281528
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|a HEALTH & FITNESS
|x Diseases
|x General.
|2 bisacsh
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|a MEDICAL
|x Clinical Medicine.
|2 bisacsh
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|a MEDICAL
|x Diseases.
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|a MEDICAL
|x Evidence-Based Medicine.
|2 bisacsh
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|a MEDICAL
|x Internal Medicine.
|2 bisacsh
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|a Myocardium
|x Regeneration
|2 fast
|0 (OCoLC)fst01031465
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1 |
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|a Li, Ren-Ke,
|e editor.
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700 |
1 |
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|a Weisel, Richard D.,
|e editor.
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776 |
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|i Print version:
|z 9781306459969
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856 |
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|u https://sciencedirect.uam.elogim.com/science/book/9780857096586
|z Texto completo
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