Cellular endocrinology in health and disease /
Cellular Endocrinology in Health and Disease describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work...
Clasificación: | Libro Electrónico |
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Otros Autores: | , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
London :
Academic Press,
2014.
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Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Hypothyroidism Retards Tumor Growth but Increases Metastasis DevelopmentDivergent Effects of TRs on Normal and Transformed Cell Proliferation; Acknowledgements; References; 2 The Molecular Cell Biology of Anterior Pituitary Cells; Introduction; Anterior Pituitary: Organization, Cell Types, Hormones and Functions; Diseases of the Anterior Pituitary; Hypopituitarism; ACTH Deficiency; TSH Deficiency; LH, FSH Deficiencies; GH Deficiency; PRL Deficiency; Hyperpituitarism; Prolactinoma; Corticotropinoma; Somatotropinoma; Null Cell Adenomas; Gonadotrophic Adenomas; Thyrotrophic Adenomas
- Phenotypic Profile of Anterior Pituitary Cell Types: Different, Yet Somewhat SimilarHeterogeneity within Anterior Pituitary Cell Types: Similar, Yet Somewhat Different; Patterns of Anterior Pituitary Cell Signaling and Secretion; Molecular Mechanisms Underlying Excitability and Basal Secretion; Receptor-Modulated Hormone Release and Voltage-Gated Ca2+ Influx through cAMP-Dependent Pathways; Receptor-Modulated Hormone Release through Ca2+-Mobilizing Pathways; Paracrine (Local) Regulation and Intercellular Signaling within the Anterior Pituitary
- Plasticity of Anterior Pituitary Cell Network Organization and FunctionConcluding Remarks; Acknowledgements; References; 3 Sensing Calcium Levels: The Biology of the Parathyroid Cell; Introduction; Biosynthesis and Metabolism of PTH; Regulation of PTH Secretion and Transcription; Calcium-Sensing Properties of the Parathyroids: The CaSR; Phospate/FGF23 Regulation of the Parathyroids; Vitamin D Regulation of the Parathyroids; Main Mechanisms of Parathyroid Gland Hyperplasia in SHPT; Conclusions; References; 4 The Biology of Pituitary Stem Cells; Introduction
- Location of Proliferating and Differentiating Cells During Pituitary DevelopmentStrategies for Identifying Pituitary Progenitors; Chromophobes Can Differentiate into All Anterior Pituitary Hormone-producing Cells; Pituitary Progenitors Absorb a Fluorescent Dipeptide and Have Folliculostellate Cell Characteristics; Pituitary Progenitors in the Side Population That Exhibit Rapid Hoechst Dye Efflux; Pituitary Progenitors in the SOX2-Positive Cell Population; Pituitary Progenitors Expressing GFRa2 and PROP1: Rodent and Human; Nestin-GFP Tagged Pituitary Progenitors