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Therapeutic antibody engineering : current and future advances driving the strongest growth area in the pharmaceutical industry /
The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of e...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cambridge, UK ; Philadelphia, PA :
Woodhead Publishing,
�2013.
|
| Colección: | Woodhead publishing series in biomedicine ;
11 |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 003 | OCoLC | ||
| 005 | 20231120111524.0 | ||
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| 008 | 110613s2013 enka ob 001 0 eng d | ||
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| 020 | |a 1907568379 |q (electronic bk.) | ||
| 020 | |a 9781907568374 |q (electronic bk.) | ||
| 020 | |z 9781306189385 | ||
| 020 | |z 1306189381 | ||
| 035 | |a (OCoLC)870891982 | ||
| 050 | 4 | |a RC271.M65 |b S77 2013eb | |
| 060 | 4 | |a QW575.5.A6 |b S77t 2013 | |
| 082 | 0 | 4 | |a 615.37 |2 23 |
| 100 | 1 | |a Strohl, W. R. | |
| 245 | 1 | 0 | |a Therapeutic antibody engineering : |b current and future advances driving the strongest growth area in the pharmaceutical industry / |c William R. Strohl and Lila M. Strohl. |
| 260 | |a Cambridge, UK ; |a Philadelphia, PA : |b Woodhead Publishing, |c �2013. | ||
| 300 | |a 1 online resource (xlvi, 650 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 0 | |a Woodhead publishing series in biomedicine ; |v 11 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 520 | |a The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of engineering monoclonal antibodies and analyses the effect that various genetic engineering approaches will have on future candidates. Chapters in the first part of the book provide an introduction to monoclonal antibodies, their discovery and development and the fundamental technologies used in their production. Following chapters cover a number of specific issues relating to different aspects of antibody engineering, including variable chain engineering, targets and mechanisms of action, classes of antibody and the use of antibody fragments, among many other topics. The last part of the book examines development issues, the interaction of human IgGs with non-human systems, and cell line development, before a conclusion looking at future issues affecting the field of therapeutic antibody engineering. Goes beyond the standard engineering issues covered by most books and delves into structure-function relationshipsIntegration of knowledge across all areas of antibody engineering, development, and marketingDiscusses how current and future genetic engineering of cell lines will pave the way for much higher productivity. | ||
| 650 | 0 | |a Monoclonal antibodies |x Therapeutic use. | |
| 650 | 0 | |a Immunotechnology. | |
| 650 | 1 | 2 | |a Antibodies, Monoclonal |x therapeutic use |0 (DNLM)D000911Q000627 |
| 650 | 1 | 2 | |a Antibodies, Monoclonal |0 (DNLM)D000911 |
| 650 | 6 | |a Anticorps monoclonaux |0 (CaQQLa)201-0085512 |x Emploi en th�erapeutique. |0 (CaQQLa)201-0373975 | |
| 650 | 6 | |a Immunotechnologie. |0 (CaQQLa)201-0294922 | |
| 650 | 7 | |a Immunotechnology |2 fast |0 (OCoLC)fst00968043 | |
| 650 | 7 | |a Monoclonal antibodies |x Therapeutic use |2 fast |0 (OCoLC)fst01025554 | |
| 655 | 4 | |a Internet Resources. | |
| 700 | 1 | |a Strohl, Lila M. | |
| 776 | 0 | 8 | |i Print version: |z 9781306189385 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9781907568374 |z Texto completo |