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Cytokine-induced pathology. Part B, Inflammatory cytokines, receptors, and diseases /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press, Inc.,
[1993]
|
| Colección: | International review of experimental pathology ;
volume 34, pt. B. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Preface; Section I Pathology Induced by Inflammatory Cytokines; Chapter 1: Introduction; I Interferon-[gamma]; II Tumor Necrosis Factor; III Interleukin-8; Chapter 2: Pathophysiologic Alterations Induced by Tumor Necrosis Factor; Publisher Summary; I Introduction; II TNF-Induced Peripheral Blood Alterations; III Organ Injury Induced by TNF; IV Additional Toxicity of TNF; V Comparison of Endogenous and Exogenous TNF; VI Inhibition of Toxicity with Anti-TNF Antibody; VII Summary; VIII Acknowledgments ; Chapter 3: In Vitro and in Vivo Activity and Pathophysiology of Human Interleukin-8 and Related PeptidesPublisher Summary; I Introduction; II Induction and Formation; III Biological Activities; IV Biological Activities in Vitro; V Discussion; VI Summary; Chapter 4: Pathology of Recombinant Human Transforming Growth Factor-[beta]1 in Rats and Rabbits; Publisher Summary; I Introduction; II Experimental Results; III Discussion; IV Summary; Acknowledgments; Chapter 5: Pathology Induced by Leukemia Inhibitory Factor; Publisher Summary; I Introduction; II Pathology Induced by LIF; III Discussion ; IV SummaryChapter 6: Comparative Pathology of Recombinant Murine Interferon--[gamma] in Mice and Recombinant Human Interferon--[gamma] in Cynomolgus Monkeys; Publisher Summary; I Introduction; II Experimental Findings; III Discussion; IV Summary; Acknowledgments; Section II Cytokine Receptors; Chapter 7: Introduction to Cytokine Receptors: Structure and Signal Transduction; Publisher Summary; I Introduction; II Tumor Necrosis Factor Receptor Family; III The Hematopoietic Growth Factor Receptor Family; IV The Immunoglobulin Supergene Family; V Other Cytokine Receptors ; Chapter 8: Pharmacokinetic Parameters and Biodistribution of Soluble Cytokine ReceptorsPublisher Summary; I Introduction; II Methods of Pharmacokinetic and Biodistribution Analysis; III Soluble IL-1 Receptor; IV Soluble IL-4 Receptor; V Soluble TNF Receptors; VI Comparison of sTNF-R Fusion Protein to sIL-4R Fusion Protein; VII Summary; Acknowledgments; Chapter 9: Immunomodulation with Soluble IFN--[gamma] Receptor: Preliminary Study; Publisher Summary; I Introduction; II IFN--[gamma] Receptor; III Soluble IFN--[gamma]R; IV Immunogenicity and Pharmacokinetic Studies of Mouse Soluble IFN--[gamma]R ; V Modulation of Graft-Versushost Disease by Soluble MoIFN--[gamma]RVI Discussion; VII Summary; Chapter 10: TNF Receptor Distribution in Human Tissues; Publisher Summary; I Introduction; II Distribution of TNF-R in Lymphoid Tissues; III TNF-R Distribution in other Tissues; IV TNF-[alpha] Expression in Tissues; V Discussion; VI Summary; Section III Role of Cytokines in Disease; Chapter 11: Tumor Necrosis Factor/Cachectin as an Effector of T Cell-Dependent Immunopathology; Publisher Summary; I Introduction; II TNF Properties Relevant for Immunopathology; III Possible Role of TNF in the Immune Response ; IV Immunopathological Reactions Involving T Lymphocytes and TNF.