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Endocrine disrupters /
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is rel...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam :
Academic Press,
�2014.
|
| Colección: | Vitamins and hormones ;
v. 94. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Front Cover; Endocrine Disrupters; Copyright; Contents; Contributors; Preface; Chapter One: Endocrine-Disrupting Chemicals and Human Growth and Maturation; 1. Introduction; 2. Challenges in Evidencing Endocrine Disruption; 3. Endocrine-Disrupting Chemicals and Fetal Growth; 4. EDCs and Sexual Differentiation; 5. EDCs and Puberty; 6. EDCs and Brain Development; 6.1. Disruption of thyroid function and brain development; 6.2. Disruption of sex steroid action and brain development; 7. EDC and Energy Balance; 8. Epigenetic Perspective on the Developmental Effects of EDCs; 9. Conclusion; References.
- Chapter Two: Agricultural Pesticides and Precocious Puberty1. Introduction; 2. Puberty; 3. Precocious Puberty; 4. The Effects of EDs on Puberty; 5. Organochlorine Pesticides and Puberty; 6. DDT and DDE; 7. Methoxychlor; 8. Endosulfans; 9. Vinclozolin; 10. Acetochlor; 11. Conclusion; References; Chapter Three: Endocrine-Disrupting Chemicals: Elucidating Our Understanding of Their Role in Sex and Gender-Relevant End ... ; 1. Introduction; 1.1. Sources of environmental contaminants; 2. Endocrine Disruption May Underlie Negative Effects of Contaminants.
- 3. Adverse Health Consequences of Lifelong EDC Exposure3.1. Cancer; 3.2. Heart disease; 3.3. Neurodegenerative diseases; 3.4. Other considerations; 4. Signficance of Investigating EDC Effects on Neurodevelopmental Processes; 5. Hormones' Effects to Organize Neural Systems and Behavioral Processes; 6. Developmental EDC Exposure Alters Reproductive Development and Behavior; 6.1. Diethylstilbestrol; 6.2. Reproductive dysfunction; 7. Exposure to EDCs in Adulthood Also Effects Reproductive Parameters; 8. EDCs in Adulthood Influence Sexually Dimorphic Brain Morphology.
- 9. Do EDCs Influence Sex Differences in Nonreproductive Behaviors?9.1. Cognitive dysfunction; 10. Effects of EDCs on Sexually Dimorphic, Nonreproductive Behaviors; 10.1. Spatial memory; 10.2. Rough-and-tumble play; 10.3. Emotional reactivity; 10.4. Stress; 11. Potential Mechanisms by which EDCs May Produce Their Effects; 11.1. Progress limitations; 12. Several Factors May Bear upon Estrogenicity of Compounds; 12.1. Mixtures; 12.2. Additivity; 12.3. Concentrations; 13. Effects of EDCs on Uterotropic Activity; 14. Importance of Examining EDC Effects on Whole-Animal Estrogenic Measures.
- 15. Effects of EDCs on E2 Metabolism16. Androgenic/Antiandrogenic Effects of EDCs; 17. Effects of EDCs via Traditional Intracellular Steroid Receptors; 18. Other Substrates to Consider for Actions of EDCs; 18.1. ER� and ER�; 18.2. Other intracellular and membrane steroid receptors; 18.3. Relevant brain areas; 19. Preliminary Studies; 20. Organized Reproductive Parameters: Immature Rats; 20.1. Perinatal androgen surge; 20.2. Anogenital distance; 21. Organized and Activated Reproductive Parameters: Peripubertal and Maturation Measures; 21.1. Accessory structures; 21.2. Puberty.