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Neural crest cells : evolution, development and disease /
Neural Crest Cells: Evolution, Development and Disease summarizes discoveries of historical significance and provides in-depth, current analyses of the evolution of neural crest cells, their contribution to embryo development, and their roles in disease. In addition, prospects for tissue engineering...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam :
Elsevier/AP,
�2014.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Neural Crest Cells: Evolution, Development and Disease; Copyright Page; Contents; Preface; Acknowledgment; Contributors; I: Neural Crest Cell Evolution and Development; 1 The Neural Crest, a Fourth Germ Layer of the Vertebrate Embryo: Significance in Chordate Evolution; General Characteristics of the Neural Crest; Transition from Invertebrates Chordates to Vertebrates; The Molecular Control of EMT Studied in NCC Development; Role of the NC in the Development of the Vertebrate Head; The Evolutionary Origin of the Vertebrate Nervous System.
- The Genetic Identity of Vertebrate Secondary Brain Organizers as Landmarks for CNS Evolution in DeuterostomesAre Precursors of the NC Present in non-vertebrate Chordates?; The Multiple Roles of the NC in the Construction of the Vertebrate Head and Brain; Hox Gene Expression in the Cephalic NC; Malformations of the Brain Induced by FSNC Removal; Effect of Forced Expression of Hox Genes in the FSNC on Face and Brain Development; Role of the Cephalic NC in the Regulation of Fgf8 Production by the ANR and Isthmus; The Evolution of Skeletal Structures in the Vertebrate Phylum.
- Conclusions and PerspectivesAbbreviations; References; 2 Induction and Specification of Neural Crest Cells: Extracellular Signals and Transcriptional Switches; Introduction; NC Induction at the NPB; Timing and Tissues; Signaling Factors; Bone Morphogenetic Protein Signaling; Wnt Signaling; Fibroblast Growth Factor Signaling; Other Signaling Pathways; Gene Regulatory Network Involved in NC Specification; NPB Specifier Genes; NC Specifier Genes; Conclusions and Perspectives; References; 3 The Cell Biology of Neural Crest Cell Delamination and EMT; Introduction; Loss of Intercellular Adhesion.
- Adherens JunctionsCadherins; Chick; Xenopus; Zebrafish and Mouse; Catenins; Tight Junctions; Claudin-1; Cingulin; Acquisition of Migratory Capacity; Rho GTPases and the Cytoskeleton; Appropriate Substrate for Migration; Breakdown of Basal Lamina; ECM; Integrins; Conclusions and Perspectives; References; 4 Neural Crest Cell Migration: Guidance, Pathways, and Cell-Cell Interactions; Pathways of Neural Crest Cell Migration: An Overview; Cephalic Neural Crest Cell Migration; Inhibitors; Positive Regulators of Cephalic Neural Crest Cell Migration; Trunk Neural Crest Cell Migration.
- The Ventromedial PathwayThe Dorsolateral Pathway; Cell-Cell Interactions During Neural Crest Cell Migration; Neural Crest-Neural Crest Interactions and Cell Polarity; Neural Crest-Neural Crest Interactions Promote Collective Guidance; CIL-Based Dispersion Is Counterbalanced by Mutual Attraction to Promote Collective Cell Migration; Dialogue Between Neural Crest Cells and Their Local Environment; Conclusion and Perspectives; Acknowledgments; References; 5 Epigenetic Regulation of Neural Crest Cells; Introduction; Histone Modifications; Methylation; Acetylation; Histone Variants.