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Tissue Engineering of the Peripheral Nerve : Stem Cells and Regeneration Promoting Factors /

This issue of International Review of Neurobiology brings together cutting-edge research on tissue engineering of the peripheral nerve. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further re...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Geuna, Stefano (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Elsevier, 2013.
Colección:International review of neurobiology ; v. 108.
Temas:
Acceso en línea:Texto completo
Texto completo
Tabla de Contenidos:
  • Front Cover; Tissue Engineering of the Peripheral Nerve: Stem Cells and Regeneration Promoting Factors; Copyright; Contents; Contributors; Preface; Chapter One: Tissue Engineering and Regenerative Medicine: Past, Present, and Future; 1. Introduction; 2. TERM: Basic Research; 2.1. Bone TE; 2.2. Cartilage TE; 2.3. Osteochondral (OCD) TE; 2.4. Meniscus TE; 2.5. Intervertebral disc (IVD) TE; 2.6. Neural TE; 2.6.1. Spinal cord injury; 2.6.2. Peripheral nerve injury; 3. New Trends in Scaffolding Technologies; 3.1. Fiber bonding; 3.2. Wet-spinning; 3.3. Rapid prototyping; 3.4. Electrospinning.
  • 3.4.1. Compression molding combined with particulate leaching3.4.2. Supercritical-assisted phase inversion; 4. Stem Cells: Looking Beyond Differentiation; 5. Conclusions; Acknowledgments; References; Chapter Two: Tissue Engineering and Peripheral Nerve Reconstruction: An Overview; 1. Reconstructive Microsurgery; 2. Transplantation; 2.1. Organ/tissue transplantation; 2.2. Cell transplantation; 2.3. Gene transfer; 3. Biomaterial Science; 4. Physical Therapy; 5. Pharmacotherapy.
  • 6. Concluding Remarks: Combining the Different Tissue Engineering Approaches, the Main Challenge for Improving Nerve Repa ... Acknowledgment; References; Chapter Three: Bone Marrow Mesenchymal Stem Cell Transplantation for Improving Nerve Regeneration; 1. Introduction; 2. Cellular and Molecular Bases of Nerve Degeneration and Regeneration; 3. Cell-Based Therapy for Improving Nerve Regeneration; 4. BM-MSC-Based Therapy; 5. Putative Mechanisms Behind the Nerve Regeneration-Promotion Potential of BM-MSCs; 6. BM-MSCs and Clinical Trials; 7. Conclusion and Future Perspectives; Acknowledgment.
  • 2.2.3. MSCs cells from a cell line and differentiation into neuroglial-like cells3. In Vivo Testing in the Rat Sciatic Nerve Model; 3.1. Surgery technique and the importance of a standardized injury; 3.2. Functional assessment; 3.3. Morphologic assessment; 4. Discussion and Final Remarks; Acknowledgments; References; Chapter Five: Adipose-Derived Stem Cells and Nerve Regeneration: Promises and Pitfalls; 1. Introduction; 2. Stem Cells for Peripheral Nerve Repair; 3. Undifferentiated Adipose-Derived Stem Cell (UASC); 4. Differentiated Adipose-Derived Stem Cell (SC-Like ASC); 5. Conclusions.