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Autophagy : cancer, other pathologies, inflammation, immunity, infection, and aging. Volume 2 /

This book aids in understanding the importance and necessity of the role of autophagy in health and disease, especially in the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. It acts as a guide to both cellular processes and their potentially important connections.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Hayat, M. A.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, CA : Academic Press, [2014]
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Autophagy :  |b cancer, other pathologies, inflammation, immunity, infection, and aging.  |n Volume 2 /  |c edited by M.A. Hayat. 
264 1 |a San Diego, CA :  |b Academic Press,  |c [2014] 
264 4 |c �2014 
300 |a 1 online resource (435 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
588 0 |a Online resource; title from PDF title page (ebrary, viewed September 19, 2013). 
505 0 |a Machine generated contents note: ch. 1 Introduction to Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volumes 1-4 -- Introduction / M.A. Hayat -- Specific Functions of Autophagy (A Summary) / M.A. Hayat -- Autophagy in Normal Mammalian Cells / M.A. Hayat -- Major Types of Autophagies / M.A. Hayat -- Selective Autophagies / M.A. Hayat -- Autophagosome Formation / M.A. Hayat -- Autophagic Lysosome Reformation / M.A. Hayat -- Autophagic Proteins / M.A. Hayat -- Monitoring Autophagy / M.A. Hayat -- Reactive Oxygen Species (ROS) / M.A. Hayat -- Mammalian Target of Rapamycin (mTOR) / M.A. Hayat -- Role of Autophagy in Tumorigenesis and Cancer / M.A. Hayat -- Role of Autophagy in Immunity / M.A. Hayat -- Role of Autophagy in Viral Defense and Replication / M.A. Hayat -- Role of Autophagy in Intracellular Bacterial Infection / M.A. Hayat -- Role of Autophagy in Heart Disease / M.A. Hayat -- Role of Autophagy in Neurodegenerative Diseases / M.A. Hayat -- Cross-Talk between Autophagy and Apoptosis / M.A. Hayat -- Autophagy and Ubiquitination / M.A. Hayat -- Autophagy and Necroptosis / M.A. Hayat -- Pexophagy / M.A. Hayat -- Mitophagy / M.A. Hayat -- Mitochondrial Fusion and Fission / M.A. Hayat -- References / M.A. Hayat -- ch. 2 Selective Autophagy: Role of Interaction between the Atg8 Family Interacting Motif and Atg8 Family Proteins / M.A. Hayat -- Introduction / Fuyuhiko Inagaki / Nobuo N. Noda -- Structural Features of Atg8 Family Proteins / Fuyuhiko Inagaki / Nobuo N. Noda -- Canonical AIM / Fuyuhiko Inagaki / Nobuo N. Noda -- Non-Canonical AIM / Fuyuhiko Inagaki / Nobuo N. Noda -- Molecular Role of AIM in Autophagy / Fuyuhiko Inagaki / Nobuo N. Noda -- Regulation of AIM-Atg / Fuyuhiko Inagaki / Nobuo N. Noda -- Interaction / Fuyuhiko Inagaki / Nobuo N. Noda -- Conclusions / Fuyuhiko Inagaki / Nobuo N. Noda -- Acknowledgments / Fuyuhiko Inagaki / Nobuo N. Noda -- References / Fuyuhiko Inagaki / Nobuo N. Noda -- ch. 3 Mammalian Autophagy Can Occur Through an Atg5/Atg7-Independent Pathway / Fuyuhiko Inagaki / Nobuo N. Noda -- Introduction / Shigeomi Shimizu / Satoko Arakawa / Tatsushi Yoshida / Hirofumi Yamaguchi / Yuya Nishida -- Discovery of the Alternative Macroautophagy Pathway / Hirofumi Yamaguchi / Tatsushi Yoshida / Yuya Nishida / Satoko Arakawa / Shigeomi Shimizu -- Origin of Alternative Macroautophagy Membrane / Shigeomi Shimizu / Satoko Arakawa / Tatsushi Yoshida / Hirofumi Yamaguchi / Yuya Nishida -- Molecular Mechanisms of Conventional and Alternative Macroautophagy / Shigeomi Shimizu / Satoko Arakawa / Tatsushi Yoshida / Hirofumi Yamaguchi / Yuya Nishida -- Atg5-Atg12 and LC3 Pathways / Shigeomi Shimizu / Satoko Arakawa / Tatsushi Yoshida / Hirofumi Yamaguchi / Yuya Nishida -- Physiological Roles of Alternative Macroautophagy / Shigeomi Shimizu / Satoko Arakawa / Tatsushi Yoshida / Hirofumi Yamaguchi / Yuya Nishida -- References / Shigeomi Shimizu / Satoko Arakawa / Tatsushi Yoshida / Hirofumi Yamaguchi / Yuya Nishida -- ch. 4 Selective Autophagy: Role of Ubiquitin and Ubiquitin-Like Proteins in Targeting Protein Aggregates, Organelles, and Pathogens / Shigeomi Shimizu / Satoko Arakawa / Yuya Nishida / Hirofumi Yamaguchi / Tatsushi Yoshida -- Introduction / Vladimir Kirkin / Vladimir Rogov -- Overview of Autophagosome Formation / Vladimir Kirkin / Vladimir Rogov -- Targeting Misfolded and Aggregated Proteins by Selective Autophagy -- Aggrephagy / Vladimir Kirkin / Vladimir Rogov -- Targeting Organelles by Selective Autophagy / Vladimir Kirkin / Vladimir Rogov -- Targeting Pathogens by Selective Autophagy -- Xenophagy / Vladimir Kirkin / Vladimir Rogov -- LIR:Atg8/LC3/GABARAP Interaction as the Driver of Selective Autophagosome Formation / Vladimir Kirkin / Vladimir Rogov -- Conclusions and Perspectives / Vladimir Kirkin / Vladimir Rogov -- References / Vladimir Kirkin / Vladimir Rogov -- ch. 5 Ubiquitin and p62 in Selective Autophagy in Mammalian Cells / Vladimir Kirkin / Vladimir Rogov -- Introduction / Peter K. Kim / Kelsey B. Law -- General Mechanism of Selective Autophagy / Peter K. Kim / Kelsey B. Law -- The Autophagy Receptor p62 / Peter K. Kim / Kelsey B. Law -- Physiological Role of Selective Autophagy / Peter K. Kim / Kelsey B. Law -- Conclusions / Peter K. Kim / Kelsey B. Law -- References / Peter K. Kim / Kelsey B. Law -- ch. 6 Role of the Golgi Complex and Autophagosome Biogenesis in Unconventional Protein Secretion / Peter K. Kim / Kelsey B. Law -- Introduction / Ravi Manjithaya / Sunaina Singh -- Secretion of Acbl/AcbA does not Depend on the Conventional ER-Golgi Secretory Pathway / Ravi Manjithaya / Sunaina Singh -- Unconventional Protein Secretion is Dependent Upon GRASP / Ravi Manjithaya / Sunaina Singh -- Role of GRASP in Trafficking of CFTR and IL-ip / Ravi Manjithaya / Sunaina Singh -- Role of Autophagy in Unconventional Protein Secretion / Ravi Manjithaya / Sunaina Singh -- Biogenesis of Vesicles for Unconventional Protein Transport / Ravi Manjithaya / Sunaina Singh -- Trafficking of the Vesicles / Ravi Manjithaya / Sunaina Singh -- Conclusions and Future Questions / Ravi Manjithaya / Sunaina Singh -- Acknowledgments / Ravi Manjithaya / Sunaina Singh -- References / Ravi Manjithaya / Sunaina Singh -- ch. 7 Induction of Autophagy in HIV-1-Uninfected Cells: Role of Fusogenic Activity of gp41 / Ravi Manjithaya / Sunaina Singh -- Introduction / Martine Biard-Piechaczyk / Lucile Espert -- HIV-1 Pathogenesis / Martine Biard-Piechaczyk / Lucile Espert -- HIV-1 and Autophagy / Martine Biard-Piechaczyk / Lucile Espert -- Role of the Fusogenic Function of gp41 in Autophagy Induction / Martine Biard-Piechaczyk / Lucile Espert -- Discussion and Conclusions / Martine Biard-Piechaczyk / Lucile Espert -- Acknowledgments / Martine Biard-Piechaczyk / Lucile Espert -- References / Martine Biard-Piechaczyk / Lucile Espert -- ch. 8 Non-Lipidated LC3 is Essential for Mouse Hepatitis Virus Infection / Martine Biard-Piechaczyk / Lucile Espert -- Coronaviruses / Julia Noack / Maurizio Molinari / Riccardo Bernasconi -- Microtubule-Associated Protein 1 Light Chain 3 (LC3) / Julia Noack / Maurizio Molinari / Riccardo Bernasconi -- Unconventional Role of Non-Lipidated LC3 in MHV Replication / Julia Noack / Maurizio Molinari / Riccardo Bernasconi -- Discussion / Julia Noack / Maurizio Molinari / Riccardo Bernasconi -- Acknowledgments / Julia Noack / Maurizio Molinari / Riccardo Bernasconi -- References / Julia Noack / Maurizio Molinari / Riccardo Bernasconi -- ch. 9 Suppression of Innate Antiviral Immunity after Hepatitis C Virus Infection: Role of the Unfolded Protein Response and Autophagy / Julia Noack / Maurizio Molinari / Riccardo Bernasconi -- Introduction / Po-Yuan Ke / Steve S.L. Chen -- Role of UPR and Autophagy in Potentiation of HCV RNA Replication / Po-Yuan Ke / Steve S.L. Chen -- Impact of UPR and Autophagy on Modulation of Innate Immune Response / Steve S.L. Chen / Po-Yuan Ke -- Discussion / Po-Yuan Ke / Steve S.L. Chen -- Acknowledgments / Po-Yuan Ke / Steve S.L. Chen -- References / Steve S.L. Chen / Po-Yuan Ke -- ch. 10 Mycobacterial Survival in Alveolar Macrophages as a Result of Coronin-1a Inhibition of Autophagosome Formation / Steve S.L. Chen / Po-Yuan Ke -- Introduction / Shintaro Seto / Kunio Tsujimura / Yukio Koide / Toshinobu Horii -- Maturation Arrest of Mycobacterial Phagosomes / Shintaro Seto / Toshinobu Horii / Kunio Tsujimura / Yukio Koide -- Coronin-1 a Recruitment to Mycobacterial Phagosomes Inhibits Phagolysosome Biogenesis / Shintaro Seto / Kunio Tsujimura / Yukio Koide / Toshinobu Horii -- Coronin-1 a Inhibits Autophagosome Formation with Regard to Mycobacteria / Shintaro Seto / Kunio Tsujimura / Toshinobu Horii / Yukio Koide -- Concluding Remarks / Shintaro Seto / Kunio Tsujimura / Yukio Koide / Toshinobu Horii -- Acknowledgments / Shintaro Seto / Kunio Tsujimura / Toshinobu Horii / Yukio Koide -- References / Shintaro Seto / Kunio Tsujimura / Yukio Koide / Toshinobu Horii -- ch.  
505 0 |a 11 Virulent Mycobacteria Upregulate Interleukin-6 (I16) Production to Combat Innate Immunity / Toshinobu Horii / Yukio Koide / Shintaro Seto / Kunio Tsujimura -- Introduction / Kapil Sharma / Mohammad Ishaq / Mohammad Aslam Khan / Gaurav Sharma / Sekhar Majumdar / Rajesh Kumar-Dutta -- Pathogenesis of Tuberculosis / Mohammad Aslam Khan / Gaurav Sharma / Rajesh Kumar-Dutta / Mohammad Ishaq / Sekhar Majumdar / Kapil Sharma -- Macrophage Response to Mtb / Rajesh Kumar-Dutta / Gaurav Sharma / Mohammad Aslam Khan / Mohammad Ishaq / Kapil Sharma / Sekhar Majumdar -- Apoptosis and Autophagy in Mycobacteria-Infected Macrophages / Rajesh Kumar-Dutta / Gaurav Sharma / Mohammad Aslam Khan / Mohammad Ishaq / Kapil Sharma / Sekhar Majumdar -- M. Tuberculosis Subverts Innate Immunity by Upscaling IL6 Production / Kapil Sharma / Sekhar Majumdar / Rajesh Kumar-Dutta / Gaurav Sharma / Mohammad Aslam Khan / Mohammad Ishaq -- Discussion / Rajesh Kumar-Dutta / Gaurav Sharma / Mohammad Aslam Khan / Mohammad Ishaq / Kapil Sharma / Sekhar Majumdar -- Acknowledgments / Rajesh Kumar-Dutta / Gaurav Sharma / Mohammad Aslam Khan / Mohammad Ishaq / Kapil Sharma / Sekhar Majumdar -- References / Rajesh Kumar-Dutta / Gaurav Sharma / Mohammad Aslam Khan / Mohammad Ishaq / Kapil Sharma / Sekhar Majumdar -- ch. 12 Autophagy in Parasitic Protists / Rajesh Kumar-Dutta / Gaurav Sharma / Sekhar Majumdar / Mohammad Ishaq / Kapil Sharma / Mohammad Aslam Khan -- Introduction / Sebastien Besteiro -- A Different Set of Autophagy Proteins in Parasitic Protists / Sebastien Besteiro -- Functions for Autophagy in Parasitic Protists / Sebastien Besteiro -- Autophagy and Host Control of Parasitemia / Sebastien Besteiro -- Future Prospects for Therapeutic Strategies / Sebastien Besteiro -- References / Sebastien Besteiro -- ch. 13 Cell Surface Pathogen Receptor CD46 Induces Autophagy / Sebastien Besteiro -- Introduction / Pierre-Emmanuel Joubert -- Cell Surface Receptor CD46 / Pierre-Emmanuel Joubert. 
505 0 |a Note continued: CD46: A Link Between Pathogens, Autophagy, and Immunity / Pierre-Emmanuel Joubert -- Discussion / Pierre-Emmanuel Joubert -- Acknowledgments / Pierre-Emmanuel Joubert -- References / Pierre-Emmanuel Joubert -- ch. 14 Helicobacter pylori Infection and Autophagy: A Paradigm for Host-Microbe Interactions / Pierre-Emmanuel Joubert -- Helicobacter Pylori / Nicola L. Jones / Ted C.H. Wu -- Autophagy / Nicola L. Jones / Ted C.H. Wu -- Helicobacter Pylori and Autophagy / Nicola L. Jones / Ted C.H. Wu -- Implications for Helicobacter Pylori Pathogenesis and Therapeutics / Nicola L. Jones / Ted C.H. Wu -- Conclusions / Nicola L. Jones / Ted C.H. Wu -- Acknowledgments / Nicola L. Jones / Ted C.H. Wu -- References / Nicola L. Jones / Ted C.H. Wu -- ch. 15 Autophagy is Required during Monocyte-Macrophage Differentiation / Nicola L. Jones / Ted C.H. Wu -- Introduction / Yan Zhang / Zhenggang Liu / Swati Choksi -- Autophagy Regulates Cell Survival and Cell Death / Yan Zhang / Zhenggang Liu / Swati Choksi -- Autophagy and Cell Differentiation / Yan Zhang / Zhenggang Liu / Swati Choksi -- Differentiation of Monocytes into Macrophages / Yan Zhang / Zhenggang Liu / Swati Choksi -- The Role of Autophagy During Monocyte/ Macrophage Differentiation / Yan Zhang / Zhenggang Liu / Swati Choksi -- Discussion / Yan Zhang / Zhenggang Liu / Swati Choksi -- Acknowledgments / Yan Zhang / Zhenggang Liu / Swati Choksi -- References / Zhenggang Liu / Swati Choksi / Yan Zhang -- ch. 16 Role of the Autophagy Gene Atg5 in T Lymphocyte Survival and Proliferation / Yan Zhang / Zhenggang Liu / Swati Choksi -- Introduction / Ming-Xiao He / You-Wen He / Ying Wan -- Cellular Function of AtgS / Ming-Xiao He / You-Wen He / Ying Wan -- Atg5 in T Lymphocyte Survival and Proliferation / Ming-Xiao He / You-Wen He / Ying Wan -- AtgS in Mitochondrial Homeostasis in T Lymphocytes / Ming-Xiao He / You-Wen He / Ying Wan -- Discussion / Ming-Xiao He / You-Wen He / Ying Wan -- Acknowledgments / Ming-Xiao He / You-Wen He / Ying Wan -- References / Ming-Xiao He / You-Wen He / Ying Wan -- ch. 17 Sepsis-Induced Autophagy is Protective Mechanism against Cell Death / Ming-Xiao He / You-Wen He / Ying Wan -- Introduction / Daniel A. Escobar / Brian S. Zucicerbraun / Hernando Gomez / Ana M. Botero -- Sepsis / Daniel A. Escobar / Ana M. Botero / Hernando Gomez / Brian S. Zucicerbraun -- Pathophysiology of Organ Failure / Daniel A. Escobar / Brian S. Zucicerbraun / Hernando Gomez / Ana M. Botero -- Autophagy / Daniel A. Escobar / Brian S. Zucicerbraun / Hernando Gomez / Ana M. Botero -- Autophagy and Sepsis / Daniel A. Escobar / Brian S. Zucicerbraun / Hernando Gomez / Ana M. Botero -- Autophagy and Immune Cell Responses / Daniel A. Escobar / Brian S. Zucicerbraun / Hernando Gomez / Ana M. Botero -- Autophagy and Organ Injury / Daniel A. Escobar / Brian S. Zucicerbraun / Hernando Gomez / Ana M. Botero -- Autophagy and Organ Injury in Sepsis / Daniel A. Escobar / Brian S. Zucicerbraun / Hernando Gomez / Ana M. Botero -- Conclusions / Daniel A. Escobar / Brian S. Zucicerbraun / Hernando Gomez / Ana M. Botero -- References / Daniel A. Escobar / Brian S. Zucicerbraun / Hernando Gomez / Ana M. Botero -- ch. 18 Blockage of Lysosomal Degradation is Detrimental to Cancer Cell Survival: Role of Autophagy Activation / Daniel A. Escobar / Brian S. Zucicerbraun / Hernando Gomez / Ana M. Botero -- Introduction / Robert Clarice / Jessica L. Schwartz-Roberts -- Lysosomes / Robert Clarice / Jessica L. Schwartz-Roberts -- Blockage of Lysosomal Degradation in Cancer / Robert Clarice / Jessica L. Schwartz-Roberts -- Discussion / Robert Clarice / Jessica L. Schwartz-Roberts -- Acknowledgments / Robert Clarice / Jessica L. Schwartz-Roberts -- References / Robert Clarice / Jessica L. Schwartz-Roberts -- ch. 19 Autophagy as a Sensitization Target in Cancer Therapy / Robert Clarice / Jessica L. Schwartz-Roberts -- Introduction / Xiao-Ming Yin / Xi Chen -- Current Strategies of Autophagy Regulation in Cancer Sensitization / Xiao-Ming Yin / Xi Chen -- Re-Evaluation of Autophagy as a Target in Cancer Sensitization / Xiao-Ming Yin / Xi Chen -- Conclusions / Xiao-Ming Yin / Xi Chen -- References / Xiao-Ming Yin / Xi Chen -- ch. 20 Pathogenesis of Bile Duct Lesions in Primary Biliary Cirrhosis: Role of Autophagy Followed by Cellular Senescence / Xiao-Ming Yin / Xi Chen -- Introduction / Yasuni Nakanuma / Matoko Sasaig -- Deregulated Autophagy in the Pathogenesis of PBC / Yasuni Nakanuma / Matoko Sasaig -- Autophagy and Cellular Senescence in PBC / Yasuni Nakanuma / Matoko Sasaig -- Conclusions / Yasuni Nakanuma / Matoko Sasaig -- References / Yasuni Nakanuma / Matoko Sasaig -- ch. 21 Autophagy and NADPH Oxidase Activity Tend to Regulate Angiogenesis in Pulmonary Artery Endothelial Cells with Pulmonary Hypertension / Yasuni Nakanuma / Matoko Sasaig -- Introduction / Ru-Jeng Teng -- Phenotypical Changes in Pulmonary Artery Endothelial Cells with PPHN / Ru-Jeng Teng -- Discussion / Ru-Jeng Teng -- Acknowledgments / Ru-Jeng Teng -- References / Ru-Jeng Teng -- ch. 22 Role of Autophagy in Heart Disease / Ru-Jeng Teng -- Introduction / Ben Loos / Anna-Mart Engelbrecht / Balindiwe Sishi -- Energetic Sensing and Signaling Pathways Involved in the Autophagic Response / Ben Loos / Anna-Mart Engelbrecht / Balindiwe Sishi -- Basal Levels of Autophagy and Starvation Response in the Heart / Ben Loos / Anna-Mart Engelbrecht / Balindiwe Sishi -- Autophagy in Ischemia/Reperfusion / Ben Loos / Anna-Mart Engelbrecht / Balindiwe Sishi -- Autophagy in Heart Failure / Ben Loos / Balindiwe Sishi / Anna-Mart Engelbrecht -- Metabolic Role of Autophagy in the Heart / Ben Loos / Balindiwe Sishi / Anna-Mart Engelbrecht -- Autophagic Flux, ATP, and Cell Death in Heart Disease / Balindiwe Sishi / Ben Loos / Anna-Mart Engelbrecht -- Autophagy and Cardiac Toxicity / Ben Loos / Balindiwe Sishi / Anna-Mart Engelbrecht -- Autophagy as a Therapeutic Target in Heart Disease / Ben Loos / Balindiwe Sishi / Anna-Mart Engelbrecht -- Future Outlook and Unanswered Questions / Balindiwe Sishi / Ben Loos / Anna-Mart Engelbrecht -- Acknowledgments / Ben Loos / Balindiwe Sishi / Anna-Mart Engelbrecht -- References / Ben Loos / Balindiwe Sishi / Anna-Mart Engelbrecht -- ch. 23 Regulation of Autophagy in Obesity-Induced Cardiac Dysfunction / Ben Loos / Balindiwe Sishi / Anna-Mart Engelbrecht -- Introduction / Xihui Xu / Jun Ren -- Obesity and Cardiac Anomalies / Xihui Xu / Jun Ren -- Autophagy / Xihui Xu / Jun Ren -- Autophagy and Obesity-Induced Cardiac Anomalies / Xihui Xu / Jun Ren -- Summary and Conclusions / Xihui Xu / Jun Ren -- References / Xihui Xu / Jun Ren -- ch. 24 Cytochrome P4502E1, Oxidative Stress, INK, and Autophagy in Acute Alcohol-Induced Fatty Liver / Xihui Xu / Jun Ren -- Introduction / Arthur I. Cederbaum -- Experimental Procedures / Arthur I. Cederbaum -- Results / Arthur I. Cederbaum -- Discussion / Arthur I. Cederbaum -- Acknowledgments / Arthur I. Cederbaum -- References / Arthur I. Cederbaum -- ch. 25 Autophagy-Independent Tumor Suppression: Role of UV Radiation Resistance Associated Gene / Arthur I. Cederbaum -- Introduction / Shanshan He / Chenoyu Limo -- UVRAG in Brief / Shanshan He / Chenoyu Limo -- UVRAG in Tumor Suppression / Shanshan He / Chenoyu Limo -- UVRAG and Endocytic Trafficking / Shanshan He / Chenoyu Limo -- UVRAG: A Gatekeeper of Chromosomal Stability / Shanshan He / Chenoyu Limo -- UVRAG and Apoptosis / Shanshan He / Chenoyu Limo -- Conclusions / Shanshan He / Chenoyu Limo -- Acknowledgments / Shanshan He / Chenoyu Limo -- References / Shanshan He / Chenoyu Limo -- ch. 26 Chaperone-Mediated Autophagy and Degradation of Mutant Huntingtin Protein / Chenoyu Limo / Shanshan He -- Introduction / Peter O. Bauer / Nobuyuki Nukina -- Mechanism of Chaperone-Mediated Autophagy / Peter O. Bauer / Nobuyuki Nukina -- Chaperone-Mediated Autophagy and Huntington's Disease / Peter O. Bauer / Nobuyuki Nukina -- CMA and Experimental Therapy of HD / Peter O. Bauer / Nobuyuki Nukina -- Acknowledgments / Peter O. Bauer / Nobuyuki Nukina -- References / Peter O. Bauer / Nobuyuki Nukina -- ch. 27 The Role of Atg8. Homologue in Lewy Body Disease / Peter O.  
505 0 |a Bauer / Nobuyuki Nukina -- Introduction / Kunikazu Tanji / Fumiaki Mori / Koichi Wakabayashi -- Atg8 Homologues are Localized in Cytoplasmic Inclusions in LBD / Kunikazu Tanji / Fumiaki Mori / Koichi Wakabayashi -- Quality of LC3 and Quantity of GABARAP are Altered in LBD / Kunikazu Tanji / Fumiaki Mori / Koichi Wakabayashi -- Discussion / Kunikazu Tanji / Fumiaki Mori / Koichi Wakabayashi -- Acknowledgments / Kunikazu Tanji / Fumiaki Mori / Koichi Wakabayashi. 
520 |a This book aids in understanding the importance and necessity of the role of autophagy in health and disease, especially in the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. It acts as a guide to both cellular processes and their potentially important connections. 
650 0 |a Cell death. 
650 0 |a Apoptosis. 
650 0 |a Homeostasis. 
650 2 |a Apoptosis  |0 (DNLM)D017209 
650 2 |a Homeostasis  |0 (DNLM)D006706 
650 6 |a Cellules  |x Mort.  |0 (CaQQLa)201-0110794 
650 6 |a Apoptose.  |0 (CaQQLa)201-0222225 
650 6 |a Hom�eostasie.  |0 (CaQQLa)201-0022624 
650 7 |a SCIENCE  |x Life Sciences  |x Anatomy & Physiology.  |2 bisacsh 
650 7 |a Apoptosis.  |2 fast  |0 (OCoLC)fst00811467 
650 7 |a Cell death.  |2 fast  |0 (OCoLC)fst00850180 
650 7 |a Homeostasis.  |2 fast  |0 (OCoLC)fst00959606 
653 0 0 |a neoplasms 
653 0 0 |a immuniteit 
653 0 0 |a immunity 
653 0 0 |a ontsteking 
653 0 0 |a inflammation 
653 0 0 |a infecties 
653 0 0 |a infections 
653 0 0 |a geneeskunde 
653 0 0 |a medicine 
653 0 0 |a pathologie 
653 0 0 |a pathology 
653 1 0 |a Medicine (General) 
653 1 0 |a Geneeskunde (algemeen) 
700 1 |a Hayat, M. A. 
776 0 8 |i Print version:  |t Autophagy.  |d San Diego, CA : Academic Press, 2014  |z 9780124058774  |w (DLC) 2013372295 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780124058774  |z Texto completo