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International review of cell and molecular biology. Volume three hundred and six /
International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transfor...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, CA :
Academic Press,
2013.
|
| Edición: | First edition. |
| Colección: | International review of cell and molecular biology,
volume three hundred and six |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
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| 019 | |a 1162050686 | ||
| 020 | |a 9780124078437 |q (electronic bk.) | ||
| 020 | |a 0124078435 |q (electronic bk.) | ||
| 020 | |z 9780124076945 | ||
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| 245 | 0 | 0 | |a International review of cell and molecular biology. |n Volume three hundred and six / |c edited by Kwang W. Jeon. |
| 250 | |a First edition. | ||
| 264 | 1 | |a San Diego, CA : |b Academic Press, |c 2013. | |
| 300 | |a 1 online resource (438 pages) : |b illustrations (some color) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 0 | |a International review of cell and molecular biology, |x 1937-6448 ; |v volume three hundred and six | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Online resource; title from PDF title page (ebrary, viewed September 19, 2013). | |
| 505 | 0 | |a Front Cover; International Review of Cell and Molecular Biology; Copyright; Contents; Contributors; Chapter One: Cell and Molecular Biology of DNA Methyltransferase 1; 1. Introduction; 2. Positions of Genomic 5-Methyl-Cytosines and Their Significance; 2.1. Symmetric and asymmetric cytosine methylation in plants and animals; 2.2. Significance of symmetric methylation; 2.3. Holliday/Pugh and Riggs postulates for inheritance of symmetric cytosine methylation; 2.4. Experimental support for maintenance methyltransferase activity; 3. Basic Molecular Mechanisms of Maintenance Methylation | |
| 505 | 8 | |a 3.1. Basic chemistry of enzymatic reaction3.2. Similarities and differences in plant and animal maintenance methyltransferases; 3.2.1. Amino acid sequence alignments; 3.2.2. Preferences for hemimethylated DNA; 3.3. Structured, highly conserved regions of DNMT1 and possible functions; 3.4. Role of accessory and interacting proteins in DNMT1 methyltransferase function; 3.5. Intrinsically disordered region of DNMT1 and possible functions; 3.6. Roles of posttranslational modifications to DNMT1; 4. Genomic Methylation During Plant and Animal Life Cycles | |
| 505 | 8 | |a 4.1. Patterns of symmetric methylation during mouse development4.2. Developmental patterns require de novo methylation, maintenance methylation, and demethylation; 4.3. Regulation of Dnmt1 expression; 4.4. DNMT1s role in imprinting; 4.5. DNMT1 and development; 4.6. Roles for Dnmt1 in DNA repair and radiation-induced DNA damage; 5. Demethylation; 5.1. Lessons from plants-Developmental, biochemical, and genetic studies; 5.2. Evidence for active demethylation in animals; 5.3. Active versus passive demethylation; 5.4. Regulating DNMT1 and demethylation; 6. De Novo Methylation | |
| 505 | 8 | |a 6.1. Lessons from plants-Biochemical and genetic studies6.2. De novo methylation mechanisms in animals; 7. Concluding Remarks; References; Chapter Two: Endothelial Progenitor Cells-Potential New Avenues to Improve Neoangiogenesis and Reendothelialization; 1. Introduction; 2. Characterization of EPC; 2.1. Isolation of EPCs; 2.1.1. Hematopoietic stem cells; 2.1.2. Early EPC/circulating angiogenic cells; 2.1.3. Late EPC/ECFC; 2.1.4. Colony-forming units according to Hill et al.; 2.1.5. MC, which differentiate into ECs under the influence of cultivation factors | |
| 505 | 8 | |a 2.1.6. Other CPCs, termed ``side population cells� � or tissue resident progenitor cells2.1.7. Circulating mature ECs that are sheared off from vessel walls; 2.2. Phenotypical characterization; 2.3. Genetic characterization; 2.4. Effects of cytokines on EPC; 2.4.1. Vascular endothelial growth factor; 2.4.2. SDF-1; 2.4.3. G-CSF/GM-CSF; 2.4.4. TNF-alpha; 2.4.5. Other cytokines and hormones; 2.4.5.1. Erythropoietin; 2.4.5.2. Estradiol; 2.4.5.3. MIF; 2.5. Cytokines expressed by EPC; 3. EPC in Health and Disease; 3.1. EPC in the healthy; 3.2. EPC in disease; 3.2.1. Cardiovascular disease | |
| 520 | |a International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2011: 4.481. * Authored by some of the foremost scientists in the field * Provides up-to-date information and directions for future research * Valuable reference material for advanced undergraduates, graduate students and professional sc. | ||
| 546 | |a English. | ||
| 650 | 0 | |a Cells. | |
| 650 | 0 | |a Molecular biology. | |
| 650 | 6 | |a Cellules. |0 (CaQQLa)201-0005079 | |
| 650 | 6 | |a Biologie mol�eculaire. |0 (CaQQLa)201-0064024 | |
| 650 | 7 | |a molecular biology. |2 aat |0 (CStmoGRI)aat300054470 | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Anatomy & Physiology. |2 bisacsh | |
| 650 | 7 | |a Cells |2 fast |0 (OCoLC)fst00850250 | |
| 650 | 7 | |a Molecular biology |2 fast |0 (OCoLC)fst01024734 | |
| 700 | 1 | |a Jeon, Kwang W. | |
| 776 | 0 | |z 0124076947 | |
| 776 | 0 | |z 1299847285 | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780124076945 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/19376448/306 |z Texto completo |