Principles of biomedical informatics /
This second edition of a pioneering technical work in biomedical informatics provides a very readable treatment of the deep computational ideas at the foundation of the field. Principles of Biomedical Informatics, 2nd Edition is radically reorganized to make it especially useable as a textbook for c...
Clasificación: | Libro Electrónico |
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Autor principal: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Amsterdam :
Elsevier/AP,
�2014.
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Edición: | Second edition. |
Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- ""Half Title""; ""Title Page""; ""Copyright""; ""Dedication""; ""Contents""; ""Preface to the Second Edition ""; ""Foreword from the First Edition ""; "" Preface from the First Edition ""; ""List of Figures""; ""List of Tables""; ""1 Biomedical Data""; ""1.1 The Nature and Representation of Biomedical Data""; ""1.1.1 What Can Be Represented in a Computer?""; ""1.1.2 Cells, DNA, Proteins, and the Genetic Code""; ""1.1.2.1 The Fundamental Dogma of Molecular Biology""; ""1.1.2.2 Representing DNA in Computer Programs""; ""1.1.2.3 FASTA Files and Reading Multiple Records""; ""1.1.3 Anatomy""
- ""1.1.4 Medical Laboratory Data""""1.1.5 Medical Images""; ""1.1.6 Metadata""; ""1.1.6.1 Tags As Metadata""; ""1.1.6.2 Source Code As Metadata""; ""1.1.6.3 Data, not Variables, Have Types""; ""1.2 Objects, Metadata, and Serialization""; ""1.2.1 A Simple Solution Using Tags (Keywords)""; ""1.2.2 An Object-Oriented Design""; ""1.2.2.1 Object-oriented Programming in Lisp""; ""1.2.2.2 A Redesign Using Classes""; ""1.2.3 A Better Solution Using Metaobjects""; ""1.2.4 Medical Images: Incorporating Binary Data""; ""1.2.4.1 Representing Image Data""; ""1.2.4.2 Reading and Writing Image Data""
- ""1.2.5 Drug Interactions: Organizing Drugs into Classes""""1.2.5.1 Drug Information Catalogs""; ""1.2.5.2 Procedural Knowledge About Enzymatic Metabolism""; ""1.2.6 XML""; ""1.3 Database Concepts and Systems""; ""1.3.1 The Relational Model""; ""1.3.1.1 A Brief Introduction to SQL""; ""1.3.1.2 Normalization""; ""1.3.1.3 Constraints and Keys""; ""1.3.1.4 Relational Algebra""; ""1.3.1.5 The Catalog, Metadata, and Object-Oriented Databases""; ""1.3.2 Indexing and Tree Structures""; ""1.3.2.1 Binary Search on Arrays""; ""1.3.2.2 Binary Search Trees""; ""1.3.2.3 Hash Tables""
- ""1.3.3 Time-Oriented Data and Interval Trees""""1.3.3.1 Constructing intervals from results""; ""1.3.3.2 Constructing an interval tree from intervals""; ""1.3.3.3 Queries and searching the interval tree""; ""1.3.4 The Entity-Attribute-Value (EAV) Model""; ""1.3.5 Online Analytical Processing (OLAP)""; ""1.3.5.1 Background""; ""1.3.5.2 OLAP fundamentals and an example""; ""1.3.5.3 Dimensions""; ""1.3.5.4 Cubes""; ""1.3.5.5 Tuples and measures""; ""1.3.5.6 Queries and the Multi-dimensional Expression Language""; ""1.3.5.7 Dihedral Angles: Query Results""
- ""1.3.5.8 Clinical trial feasibility: a second example""""1.4 Data Quality""; ""1.5 Data, Information, and Knowledge""; ""1.6 Summary""; ""1.7 Exercises""; ""2 Symbolic Biomedical Knowledge""; ""2.1 Biomedical Theories and Computer Programs""; ""2.1.1 A World Class Reasoning Example""; ""2.1.2 Biological Examples""; ""2.1.3 Symbolic Theories""; ""2.2 Logic and Inference Systems""; ""2.2.1 Predicate Calculus""; ""2.2.1.1 Truth and Consequences""; ""2.2.1.2 Inference Rules""; ""2.2.1.3 Theorems and Proofs""; ""2.2.1.4 Automated Proof Methods""