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Advances in molecular toxicology Volume 7 /
Advances in Molecular Toxicology features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment and produced by the human body manife...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam, Netherlands ; Oxford, England :
Academic Press,
�2013.
|
| Edición: | 1st ed. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
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| 005 | 20231117044919.0 | ||
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| 019 | |a 1162047582 | ||
| 020 | |a 9780444626554 |q (electronic bk.) | ||
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| 020 | |a 9780128022290 |q (electronic bk.) | ||
| 020 | |a 0128022299 |q (electronic bk.) | ||
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| 035 | |a (OCoLC)859158730 |z (OCoLC)1162047582 | ||
| 050 | 4 | |a RA1211 |b .A383 2013eb | |
| 082 | 0 | 4 | |a 615.9 |2 23 |
| 245 | 0 | 0 | |a Advances in molecular toxicology |n Volume 7 / |c edited by James C. Fishbein, Jacqueline M. Heilman. |
| 250 | |a 1st ed. | ||
| 260 | |a Amsterdam, Netherlands ; |a Oxford, England : |b Academic Press, |c �2013. | ||
| 300 | |a 1 online resource (xii, 241 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Included bibliographical references at the end of each chapters and index. | ||
| 588 | 0 | |a Online resource; title from title page (ebrary, viewed August 27, 2013). | |
| 520 | |a Advances in Molecular Toxicology features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment and produced by the human body manifest themselves as toxins. The book is not strictly limited to documenting these examples, but also covers the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field. | ||
| 505 | 0 | |a Front Cover; Advances in Molecular Toxicology; Copyright; Contents; Contributors; Preface; Chapter One: AHR- and ER-Mediated Toxicology and Chemoprevention; 1. Introduction; 2. AHR Ligands; 2.1. Natural and/or dietary ligands; 2.2. Endogenous ligands; 3. Aryl Hydrocarbon Receptor; 3.1. Mechanism of AHR transactivation; 3.2. The nongenomic pathway; 3.3. Negative feedback regulation of AHR transactivation; 3.4. AHR-regulated signaling and toxicity; 3.5. Adverse human health effects of dioxin-like compounds; 3.6. Adaptive response pathway; 3.7. Developmental pathway | |
| 505 | 8 | |a 6.2. Phenylenediamine arylamine xenobiotics7. Arylamine Drugs and Blood Dyscrasias; 7.1. Procainamide; 7.2. Aminoglutethimide; 7.3. Aminopyrine; 8. Diverting Toxic Arylamine Free Radical Generation to Detoxification: Importance of Free Radical Targets; 9. Mixtures Toxicology-Application to Arylamine Free Radicals; 10. Protein Radicals and Toxicity-Future Prospects; 11. Closing Remarks; References; Chapter Three: Genotoxicity of Polycyclic Aromatic Hydrocarbon Metabolites: Radical Cations and Ketones; 1. Introduction; 2. Exposure to PAHs; 3. Exposure Risks of PAH; 4. DNA Damage by PAH | |
| 505 | 8 | |a 5. PAH Metabolism to DNA-Reactive Metabolites6. Diol-Epoxide Pathway; 7. The Radical Cation Pathway; 8. Depurinating PAH Adducts and AP Sites; 9. Mutagenesis Studies to Address PAH Radical Cations; 10. Evidence for AP Site Formation Due to Radical Cations; 11. Mutagenicity Studies with B[a]P Radical Cation Products; 12. The Quinone Pathway; 13. Exposure to OPAHs; 14. Biological Relevance of OPAH; 15. Conclusion; References; Chapter Four: Nitrogen Oxides Toxicology of the Aerodigestive Tract; 1. Introduction; 2. Chemistry of Reactive Oxygen and Nitrogen Oxide Species and the Scavengers | |
| 546 | |a English. | ||
| 650 | 0 | |a Toxicology. | |
| 650 | 0 | |a Molecular biology. | |
| 650 | 2 | |a Toxicology |0 (DNLM)D014116 | |
| 650 | 2 | |a Molecular Biology |0 (DNLM)D008967 | |
| 650 | 6 | |a Toxicologie. |0 (CaQQLa)201-0054329 | |
| 650 | 6 | |a Biologie mol�eculaire. |0 (CaQQLa)201-0064024 | |
| 650 | 7 | |a toxicology. |2 aat |0 (CStmoGRI)aat300251568 | |
| 650 | 7 | |a molecular biology. |2 aat |0 (CStmoGRI)aat300054470 | |
| 650 | 7 | |a Molecular biology |2 fast |0 (OCoLC)fst01024734 | |
| 650 | 7 | |a Toxicology |2 fast |0 (OCoLC)fst01153364 | |
| 700 | 1 | |a Fishbein, James C. | |
| 700 | 1 | |a Heilman, Jacqueline M. | |
| 776 | |z 0-444-62645-X | ||
| 776 | |z 1-299-78896-3 | ||
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128022290 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/18720854/9 |z Texto completo |