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Genomic biomarkers for pharmaceutical development : advancing personalized health care /
Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care provides an in-depth review of the state of translational science across all stages of pharmaceutical development with a special focus on personalized health care. This book provides a complete picture of biomarker...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, Calif. :
Academic Press,
2014.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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|---|---|---|---|
| 001 | SCIDIR_ocn857079388 | ||
| 003 | OCoLC | ||
| 005 | 20231117044916.0 | ||
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| 008 | 130730s2014 caua ob 001 0 eng d | ||
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| 020 | |a 9780123977946 |q (e-book) | ||
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| 020 | |z 9780123973368 | ||
| 020 | |z 0123973368 | ||
| 035 | |a (OCoLC)857079388 |z (OCoLC)1065810303 |z (OCoLC)1235843116 | ||
| 050 | 4 | |a RS380 |b .G46 2014eb | |
| 060 | 4 | |a 2013 J-426 | |
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| 072 | 7 | |a SCI |x 029000 |2 bisacsh | |
| 082 | 0 | 4 | |a 615.3 |2 23 |
| 245 | 0 | 0 | |a Genomic biomarkers for pharmaceutical development : |b advancing personalized health care / |c edited by Yihong Yao, Bahija Jallal, Koustubh Ranade. |
| 260 | |a San Diego, Calif. : |b Academic Press, |c 2014. | ||
| 300 | |a 1 online resource (xi, 190 pages) : |b illustrations (some color) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care provides an in-depth review of the state of translational science across all stages of pharmaceutical development with a special focus on personalized health care. This book provides a complete picture of biomarker development and validation in a pharmaceutical setting while addressing the inherent challenges of targeting the appropriate indications, biomarker robustness, regulatory hurdles, commercialization and much more. It features case studies devoted to the applications of pharmacogenomics, toxicogenomics, and other genetic technologies as they support drug discovery and development. With chapters written by international authorities in industry and academia, this work is a truly unique presentation of the thoughts and approaches that lead to the development of personalized medicine. Intended for all those involved in clinical translational research, this book is the ideal resource for scientists searching for the applications, strategies and successful approaches of translational science in pharmaceutical development. Provides case studies in applications of pharmacodynamic and predictive markers in drug development in oncology, autoimmunity, respiratory diseases and infectious diseases. Shows how to identify potential new therapeutic targets in different diseases and provides examples of potential new disease indications for life cycle management of drugs. Authored by leading international experts from industry and academia. | ||
| 505 | 0 | |a 1. Application of translational science to clinical development / Koustubh Ranade [and five others] -- 2. Personalized health care (PHC) in cancer / Nicholas C. Dracopoli, Katie Streicher -- 3. Personalized healthcare in autoimmune diseases / Cornelis L. Verweij, Brandon W. Higgs, Yihong Yao -- 4. Molecular heterogeneity, biomarker discovery, and targeted therapy in asthma / Joseph R. Arron, Jeffrey M. Harris -- 5. microRNA biomarkers as potential diagnostic markers for cancer / Elizabeth Mambo [and five others] -- 6. Toxicogenomics -- a drug development perspective / Yuping Wang, Jurgen Borlak, Weida Tong -- 7. Translating biomarker discovery into companion diagnostics through validation and regulatory consideration / Philip Brohawn [and four others]. | |
| 650 | 0 | |a Pharmaceutical biotechnology. | |
| 650 | 0 | |a Drug development. | |
| 650 | 0 | |a Genomics. | |
| 650 | 2 | |a Translational Research, Biomedical |0 (DNLM)D057170 | |
| 650 | 1 | 2 | |a Biomarkers, Pharmacological |0 (DNLM)D054316 |
| 650 | 2 | 2 | |a Genomics |0 (DNLM)D023281 |
| 650 | 6 | |a Biotechnologie pharmaceutique. |0 (CaQQLa)201-0229592 | |
| 650 | 6 | |a M�edicaments |x D�eveloppement. |0 (CaQQLa)201-0306620 | |
| 650 | 6 | |a G�enomique. |0 (CaQQLa)201-0363181 | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Genetics & Genomics. |2 bisacsh | |
| 650 | 7 | |a Drug development |2 fast |0 (OCoLC)fst00898670 | |
| 650 | 7 | |a Genomics |2 fast |0 (OCoLC)fst00940228 | |
| 650 | 7 | |a Pharmaceutical biotechnology |2 fast |0 (OCoLC)fst01060106 | |
| 655 | 4 | |a Internet Resources. | |
| 655 | 4 | |a Portraits. | |
| 700 | 1 | |a Yao, Yihong |c (Head of pharmacogenomics and bioinformatics) | |
| 700 | 1 | |a Jallal, Bahija. | |
| 700 | 1 | |a Ranade, Koustubh. | |
| 776 | 0 | 8 | |i Online version: |t Genomic biomarkers for pharmaceutical development. |d San Diego, Calif. : Academic Press, 2014 |z 9780123973368 |w (OCoLC)857079388 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780123973368 |z Texto completo |