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Autophagy : Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 1 /
Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward thinking, these books offer a valuable guide to both cellular processes while incitin...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston :
Elsevier Science,
2014.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Degradation of ALS-Linked Mutant SOD1 by MacroautophagyInteraction between Parkinson's Disease-Associated UCH-L1 and Chaperone-Mediated Autophagy; Degradation of RNA by Rnautophagy: Its Possible Roles in Neurodegenerative Disorders; References; 5 Autophagy and Crohn's Disease: Towards New Therapeutic Connections; Introduction: Crohn's Disease and Faulty Autophagy go Hand in Hand; Autophagy: A Hot Novel Target or an Old Friend?; Autophagy Regulates Immunity; Anti-TNF-[alpha]; Thiopurines; Curcumin; Direct Autophagy Modulators; Diagnostic Value of the Autophagic Status; Concluding Remarks; References.
- Front Cover; Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging; Copyright Page; Dedication; Contents; Preface; Contributors; List of Contributions Projected in Volumes 2-4; Abbreviations and Glossary; 1 Introduction to Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection and Aging, Volumes 1-4; Introduction; Specific Functions of Autophagy (A Summary); Autophagy in Normal Mammalian Cells; Major Types of Autophagies; Macroautophagy (Autophagy); Microautophagy; Chaperone-Mediated Autophagy; Selective Autophagies; Autophagosome Formation.
- Autophagic Lysosome ReformationAutophagic Proteins; Protein Degradation Systems; Beclin 1; Non-Autophagic Function of Autophagy-Related Proteins; Microtubule-Associated Protein Light Chain 3; Monitoring Autophagy; Reactive Oxygen Species (ROS); Mammalian Target of Rapamycin (mTOR); Role of Autophagy in Tumorigenesis and Cancer; Role of Autophagy in Immunity; Role of Autophagy in Viral Defense and Replication; Role of Autophagy in Intracellular Bacterial Infection; Role of Autophagy in Heart Disease; Role of Autophagy in Neurodegenerative Diseases; Cross-Talk between Autophagy and Apoptosis.
- Pathway and Mechanism for AutophagyInitiation; Nucleation; Elongation; Maturation/Fusion with Lysosomes; Physiological Roles of Autophagy; Autophagy and Neuronal Physiology; Quality Control; Development and Differentiation; Autophagy and Neurodegenerative Diseases; Alzheimer's Disease; Parkinson's Disease; Huntington's Disease; Amyotrophic Lateral Sclerosis; Frontotemporal Dementia; Cerebral Ischemia (Injury); Conclusions and Future Perspective; Acknowledgments; References; 4 Roles of Multiple Types of Autophagy in Neurodegenerative Diseases.