Cargando…
Advances in genetics. Volume 83 /
The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. * Includes methods...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam :
Academic Press,
2013.
|
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
| LEADER | 00000cam a2200000 a 4500 | ||
|---|---|---|---|
| 001 | SCIDIR_ocn854760495 | ||
| 003 | OCoLC | ||
| 005 | 20231117044910.0 | ||
| 006 | m o d | ||
| 007 | cr cnu---unuuu | ||
| 008 | 130731s2013 ne o 000 0 eng d | ||
| 040 | |a N$T |b eng |e pn |c N$T |d OPELS |d CDX |d OCLCQ |d OCLCF |d OCLCQ |d OCLCO |d E7B |d EBLCP |d UKDOC |d DEBSZ |d OCLCQ |d DEBBG |d D6H |d OCLCQ |d OCLCO |d INARC |d OCLCQ |d OCLCO | ||
| 019 | |a 854977087 |a 857070035 | ||
| 020 | |a 9780124078017 |q (electronic bk.) | ||
| 020 | |a 012407801X |q (electronic bk.) | ||
| 020 | |z 9780124076754 | ||
| 020 | |z 0124076750 | ||
| 035 | |a (OCoLC)854760495 |z (OCoLC)854977087 |z (OCoLC)857070035 | ||
| 050 | 4 | |a QH430 | |
| 072 | 7 | |a SCI |x 029000 |2 bisacsh | |
| 082 | 0 | 4 | |a 576.5 |2 23 |
| 245 | 0 | 0 | |a Advances in genetics. |n Volume 83 / |c edited by Theodore Friedmann, Jay Dunlap, Stephen Goodwin. |
| 264 | 1 | |a Amsterdam : |b Academic Press, |c 2013. | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 520 | |a The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. * Includes methods for testing with ethical, legal, and social implications * Critically analyzes future. | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Front Cover; Advances in Genetics; Copyright; Contents; Contributors; Chapter One: Biology and Mechanisms of Short RNAs in Caenorhabditis elegans; 1. Introduction; 2. miRNA Function; 2.1. Biological effects of miRNAs; 2.1.1. Developmental timing; 2.1.2. Embryonic development; 2.1.3. Postembryonic development; 2.1.4. Physiology; 2.1.5. Longevity and stress response; 2.2. Biogenesis and molecular mechanisms of miRNAs; 3. RNAi and Endogenous siRNAs; 3.1. Exogenous RNAi pathway; 3.1.1. RDE-4 and Dicer; 3.1.2. RDE-1 Argonaute protein; 3.1.3. siRNA amplification and additional Argonautes. | |
| 505 | 8 | |a 3.1.4. Mutator proteins3.1.5. ABC transporters; 3.1.6. RDE-10/RDE-11 complex; 3.1.7. Transcriptional silencing induced by dsRNA; 3.1.8. Inheritance of dsRNA-induced gene silencing; 3.1.9. Chromatin modulators of the RNAi response; 3.2. Genomic and molecular features of endogenous RNAi; 3.2.1. Discovery of endo-siRNAs; 3.2.2. Distinction between WAGO- and CSR-1-associated 22G-endo-siRNAs; 3.2.3. 26G- and 22G-endo-siRNAs of the ERI pathway; 3.2.4. Competition between ADARs and endogenous RNAi; 3.3. Biological functions of RNAi; 3.3.1. Antiviral defense. | |
| 505 | 8 | |a 3.3.2. Silencing of transposons and repetitive elements3.3.3. A summary of the global effects of 22G-RNAs on the expression of endogenous genes; 3.3.4. Endogenous RNAi and adaptation to environment; 3.3.5. Developmental roles of the CSR-1 22G-RNA pathway; 3.3.6. Cooperation between RNAi and Rb; 3.3.7. The role of ALG-3/4 endo-siRNAs in sperm development; 4. 21U-RNAs, C. elegans piRNAs; 4.1. Biogenesis of 21U-RNAs; 4.2. Biological functions of 21U-RNAs; 4.2.1. Function in fertility; 4.2.2. Connection between 21U-RNAs, 22G-RNA production, and stable silencing of foreign DNA. | |
| 505 | 8 | |a 5. Systemic Features of RNAi5.1. dsRNA import channel SID-1 and the features of mobile RNA species; 5.2. Additional factors required for systemic and environmental RNAi; 5.2.1. SID-2; 5.2.2. SID-3; 5.2.3. SID-5; 6. Outlook; Acknowledgments; References; Chapter Two: Genetics of Immune Recognition and Response in Drosophila host defense; 1. Introduction; 1.1. Overview of Drosophila immune responses; 2. Toll Signaling in Drosophila; 2.1. Activation; 2.1.1. The Necrotic-Persephone axis; 2.1.2. PGRPs and GNBPs; 2.1.3. Mechanism of sensing bacterial and fungal cell wall components. | |
| 505 | 8 | |a 2.1.4. Ligand activation: The role of Spz2.2. Intracellular signaling; 2.3. Host-pathogen interaction upstream of Toll; 3. The Immune Deficiency Pathway; 3.1. Recognition and intracellular signaling; 3.2. Gut immunity and IMD signaling; 3.3. Host-pathogen interaction; 4. Immunity as a Sensor of Metabolism; 5. Concluding Remarks-Future Directions; Acknowledgments; References; Chapter Three: Recent Advances in Septum Biogenesis in Neurospora crassa; 1. Introduction; 2. Septum Ontogeny; 2.1. Septation during hyphal development; 2.2. Septation establishment: Regulators and positional markers. | |
| 650 | 0 | |a Genetics. | |
| 650 | 2 | |a Genetics |0 (DNLM)D005823 | |
| 650 | 6 | |a G�en�etique. |0 (CaQQLa)201-0069234 | |
| 650 | 7 | |a genetics. |2 aat |0 (CStmoGRI)aat300138822 | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Genetics & Genomics. |2 bisacsh | |
| 650 | 7 | |a Genetics |2 fast |0 (OCoLC)fst00940117 | |
| 700 | 1 | |a Friedmann, Theodore, |d 1935- |e editor. | |
| 700 | 1 | |a Dunlap, Jay C., |e editor. | |
| 700 | 1 | |a Goodwin, Stephen F., |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Advances in genetics. Volume 83 |z 9780124076754 |w (OCoLC)853505664 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780124076754 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00652660/83 |z Texto completo |