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Hormones and Breast Cancer /

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms. Under the capable and qualified editorial le...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Litwack, Gerald (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: North Hollywood, CA : Elsevier Science & Technology, 2013.
Edición:First edition.
Colección:Vitamins and hormones ; v. 93.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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245 0 0 |a Hormones and Breast Cancer /  |c editor in chief, Gerald Litwack. 
250 |a First edition. 
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520 |a First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologica. 
505 0 |a Front Cover; Hormones and Breast Cancer; Copyright; Former Editors; Contents; Contributors; Preface; Chapter One: Estrogen-Mediated Mechanisms to Control the Growth and Apoptosis of Breast Cancer Cells: A Translational Res ...; 1. Introduction; 2. Clinical Presentation of Breast Cancer; 3. Targeted Therapy; 3.1. Foundations of chemical therapy; 3.2. The first chemical therapy to treat cancer; 3.3. Nonsteroidal antiestrogens; 4. Transition to Tamoxifen; 5. Selective Estrogen Receptor Modulation; 6. Acquired Drug Resistance and the Surprise of SERMs 
505 8 |a 7. Estrogen-Induced Apoptosis: Back to the Beginning8. The Legacy of Tamoxifen; Acknowledgments; References; Chapter Two: The Epidemiology and Molecular Mechanisms Linking Obesity, Diabetes, and Cancer; 1. Introduction; 2. Type 2 Diabetes and Breast Cancer; 2.1. Epidemiology; 2.1.1. Type 2 diabetes and cancer; 2.1.2. Hyperinsulinemia and breast cancer; 2.2. Insulin and insulin receptor signaling in cancer; 2.2.1. The dual role of insulin; 2.2.2. Insulin as a metabolic regulator; 2.2.3. Insulin as a mitogen; 2.2.4. IR isoforms, hybrids, and cancer 
505 8 |a 2.2.5. Insulin resistance, hyperinsulinemia, and breast cancer2.3. IGF signaling and breast cancer; 3. The Role of Cholesterol in Cancer Growth; 3.1. Epidemiological studies linking cholesterol and cancer; 3.1.1. Breast cancer; 3.1.2. Prostate cancer; 3.2. Molecular mechanisms linking cholesterol to cancer growth; 3.2.1. Cholesterol and breast cancer; 3.2.2. Cholesterol and prostate cancer; 3.2.3. Cholesterol in other tumor types; 3.3. Cholesterol and statins; 4. Obesity, Estrogen, and Breast Cancer; 4.1. Obesity and circulating estrogens; 4.2. Obesity and breast aromatase activity 
505 8 |a 4.3. Estrogen receptor and breast cancer in obesity and type 2 diabetes4.3.1. Estrogen receptor signaling; 4.3.2. ER and IGF-1R cross talk in breast cancer; 4.3.3. ER and IR signaling in hormone refractory breast cancers; 5. Current Medications for Type 2 Diabetes: Relationship to Breast Cancer; 5.1. Recombinant insulin and insulin analogs; 5.2. Insulin secretagogues; 5.3. Insulin sensitizers (biguanides and thiazolidinediones); 6. Conclusions and Future Directions; References; Chapter Three: Sex Hormone Receptors in Breast Cancer; 1. Introduction; 2. Historical Perspective 
650 0 |a Breast  |x Cancer. 
650 0 |a Hormones  |x Cancer. 
650 2 |a Breast Neoplasms  |0 (DNLM)D001943 
650 6 |a Sein  |x Cancer.  |0 (CaQQLa)201-0071080 
650 6 |a Hormones  |0 (CaQQLa)201-0017163  |x Cancer.  |0 (CaQQLa)201-0378838 
650 7 |a HEALTH & FITNESS  |x Diseases  |x Cancer.  |2 bisacsh 
650 7 |a MEDICAL  |x Oncology.  |2 bisacsh 
650 7 |a Breast  |x Cancer  |2 fast  |0 (OCoLC)fst00838260 
700 1 |a Litwack, Gerald,  |e editor. 
776 0 8 |i Print version:  |z 9781299700918 
830 0 |a Vitamins and hormones ;  |v v. 93. 
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