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|a 616.716
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|a Osteoporosis /
|c edited by Robert Marcus, David Feldman, David W. Dempster, Marjorie Luckey, Jane A. Cauley.
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250 |
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|a Fourth edition.
|
264 |
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1 |
|a Amsterdam :
|b Elsevier/Academic Press,
|c 2013.
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300 |
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|a 1 online resource (2 volumes (xxv, 1995 pages, 18 unnumbered pages of plates)) :
|b illustrations (chiefly color)
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|a ClinicalKey
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|a Previous edition: 2008.
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504 |
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|a Includes bibliographical references and index.
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0 |
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|a V: 1 -- The bone organ system: form and function -- The nature of osteoporosis -- Reflections on osteoporosis -- Reflections on development of concepts of intercellular communication in bone -- Osteo-odyssey: a memoir -- Development of the skeleton -- The skeletal stem cell -- Osteoclast biology -- Osteoblast biology -- Osteocyte biology -- The regulatory role of matrix protein in mineralization of bone -- Parathyroid hormone and parathyroid hormone-related protein -- Vitamin D: biology, actions, and clinical implications -- Regulation of bone cell function by estrogens -- Androgens and skeletal biology: basic mechanisms -- Phosphatonins -- Skeletal growth factors -- Wnt signaling in skeletal homeostasis and diseases -- The mechanical behavior of bone -- Cellular and molecular mechanotransduction in bone -- Adaptation of skeletal structure to mechanical loading -- Biomechanics of hip and vertebral fractures -- Prevention of osteoporosis by physical signals: defining a potential role for nondrug strategies in the treatment of musculoskeletal injury and disease -- Epidemiologic methods in studies of osteoporosis -- Genetic determinants of osteoporosis -- Race, ethnicity, and osteoporosis -- Geographic variability in hip and vertebral fractures -- Nutrition and risk for osteoporosis -- Physical activity and exercise in the maintenance of the adult skeleton and the prevention of osteoporotic fractures -- Premenopausal reproductive and hormonal characteristics and the risk for osteoporosis -- Clinical and epidemiological studies: skeletal changes across menopause -- Osteoporosis in men: epidemiology, pathophysiology, and clinical characterization -- Falls as risk factors for fracture -- Nonskeletal risk factors for osteoporosis and fractures -- Outcomes following osteoporotic fractures -- Skeletal heterogeneity and the purposes of bone remodeling: implications for the understanding of osteoporosis -- On the evolution and contemporary roles of bone remodeling -- Cytokines and the pathogenesis of osteoporosis -- Animal models for osteoporosis -- Bone and fat -- Bone mineral acquisition in utero and during infancy and childhood -- Bone acquisition in adolescence.
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505 |
0 |
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|a V: 2 -- Osteoporosis in childhood and adolescence -- Osteoporosis associated with pregnancy -- Osteoporosis in premenopausal women -- Estrogen deficiency, postmenopausal osteoporosis, and age-related bone loss -- Immobilization osteoporosis -- Osteoporosis associated with illnesses and medications -- Glucocorticoid-induced osteoporosis -- Anticonvulsant-related bone disease -- Thyroid hormone and the skeleton -- The skeletal actions of parathyroid hormone in primary hyperparathyroidism and in osteoporosis -- Osteogenesis imperfecta and other defects of bone development as occasional causes of adult osteoporosis -- HIV and osteoporosis -- Obesity, diabetes, and fractures -- Osteoporosis in organ transplant patients -- Osteoporosis associated with rheumatologic disorders -- Osteoporosis associated with chronic kidney disease -- Oral bone loss and systemic osteoporosis: weighing the risk benefit ratio of treatment -- Cancer treatment-induced bone loss in patients with breast cancer: pathophysiology and clinical perspectives -- Pathophysiology-prostate cancer -- Mechanisms of bone destruction in myeloma -- Evaluation of the patient at risk for osteoporosis -- Imaging of osteoporosis -- Osteoporosis: who should be treated? Who should be screened? -- Clinical use of bone densitometry -- Biochemical markers of bone turnover in osteoporosis -- Fracture risk assessment: the development and application of FRAX� -- Orthopedic aspects of osteoporosis -- Falls prevention interventions -- Physical therapy, physical modalities, and exercise regimens in the management of osteoporosis -- Calcium in the treatment of osteoporosis -- Vitamin D and its metabolities and analogs in the management of osteoporosis -- Alternative therapy through nutrients and nutraceuticals -- Design considerations for clinical investigations of osteoporosis -- Lessons from bone histomorphometry on the mechanisms of action of osteoporosis drugs -- Estrogen and estrogen analogs for prevention and treatment of osteoporosis -- Androgens -- Calcitonin in osteoporosis -- Bisphosphonates: pharmacology and use in the treatment of osteoporosis -- Osteonecrosis of the jaw and atypical femoral fractures -- Condition critical: compliance and persistence with osteoporosis medications -- Denosumab for the treatment of osteoporosis -- Strontium ranelate in the prevention of osteoporotic fractures -- Parathyroid hormone treatment for osteoporosis -- New approaches to osteoporosis therapeutics -- The past, present, and uncertain future of therapeutic innovation in osteoporosis.
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588 |
0 |
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|a Print version record.
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520 |
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|a Now in its third edition, Osteoporosis, is the most comprehensive, authoritative reference on this disease. Written by renowned experts in the field, this two-volume reference is a must-have for academic and medical libraries, physicians, researchers, and any company involved in osteoporosis research and development. Worldwide, 200 million women between 60-80 suffer from osteoporosis and have a lifetime risk of fracture between 30 and 40 % continuing to make osteoporosis a hot topic in medicine.
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546 |
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|a English.
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650 |
|
0 |
|a Osteoporosis.
|
650 |
|
2 |
|a Fractures, Bone
|x pathology
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650 |
|
2 |
|a Osteoporosis
|0 (DNLM)D010024
|
650 |
|
2 |
|a Osteporosis
|x therapy
|
650 |
2 |
2 |
|a Osteoporosis
|x therapy
|0 (DNLM)D010024Q000628
|
650 |
|
6 |
|a Ost�eoporose.
|0 (CaQQLa)201-0045672
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650 |
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|a HEALTH & FITNESS
|x Diseases
|x Musculoskeletal.
|2 bisacsh
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650 |
|
7 |
|a MEDICAL
|x Orthopedics.
|2 bisacsh
|
650 |
|
7 |
|a MEDICAL
|x Rheumatology.
|2 bisacsh
|
650 |
|
7 |
|a Osteoporosis
|2 fast
|0 (OCoLC)fst01048817
|
655 |
|
0 |
|a Osteoporosis.
|
700 |
1 |
|
|a Marcus, Robert,
|d 1940-
|e editor.
|
700 |
1 |
|
|a Feldman, David,
|d 1939-
|e editor.
|
700 |
1 |
|
|a Dempster, David W.,
|e editor.
|
700 |
1 |
|
|a Luckey, Marjorie,
|e editor.
|
700 |
1 |
|
|a Cauley, Jane A.,
|e editor.
|
776 |
0 |
8 |
|i Print version:
|t Osteoporosis.
|b Fourth edition.
|d Amsterdam : Elsevier/Academic Press, 2013
|z 9780124158535
|w (OCoLC)839312872
|
830 |
|
0 |
|a ClinicalKey.
|
856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780124158535
|z Texto completo
|