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Cancer immunotherapy : immune suppression and tumor growth /

"This book highlights new principles of immune suppression that drive cancer, and offers radically new ideas about how therapy can be improved by attacking these principles. It provides an overview of immune escape as a critical trait in cancer and how applying specific combinations of immunoth...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Prendergast, George C. (Editor ), Jaffee, Elizabeth M. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Elsevier/Academic Press, [2013]
Edición:Second edition.
Temas:
Acceso en línea:Texto completo

MARC

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019 |a 849951712  |a 851315809  |a 862573261  |a 1019915916  |a 1043065791 
020 |a 9780123946331  |q (electronic bk.) 
020 |a 0123946336  |q (electronic bk.) 
020 |z 9780123942968  |q (p-ISBN) 
020 |z 0123942969  |q (p-ISBN) 
035 |a (OCoLC)847527218  |z (OCoLC)849951712  |z (OCoLC)851315809  |z (OCoLC)862573261  |z (OCoLC)1019915916  |z (OCoLC)1043065791 
050 4 |a RC271.I45 
060 4 |a QZ 266 
072 7 |a HEA  |x 039030  |2 bisacsh 
072 7 |a MED  |x 062000  |2 bisacsh 
082 0 4 |a 616.994061  |2 23 
130 0 |a Cancer immunotherapy (Prendergast) 
245 1 0 |a Cancer immunotherapy :  |b immune suppression and tumor growth /  |c edited by George Prendergast, Elizabeth M. Jaffee. 
250 |a Second edition. 
264 1 |a San Diego :  |b Elsevier/Academic Press,  |c [2013] 
264 4 |c �2013 
300 |a 1 online resource (xxii, 655 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
588 0 |a Online resource; title from resource home page (ebrary, viewed October 27, 2015). 
504 |a Includes bibliographical references and index. 
505 0 |a Section 1: Principles of basic immunology. Components of the immune system -- Adaptive immunity: B cells and antibodies -- Adaptive immunity: T cells and cytokines -- Dendritic cells: antigen processing and presentation -- Mucosal immunity -- Section 2: Principles of cancer immunobiology. Cancer immunoediting: from surveillance to escape -- Immunosurveillance: innate and adaptive antitumor immunity -- Immunological sculpting: natural killer-cell receptors and ligands -- Th17 cells in cancer -- Immune escape: immunosuppressive networks -- Section 3: Introduction to cancer therapeutics. Principles of cytotoxic chemotherapy -- Pharmacokinetics and safety assessment -- Monoclonal antibodies for cancer therapy and prevention: paradigm studies in targeting the neu/ERBB2/HER2 oncoprotein -- Genetic vaccines against cancer: design, testing and clinical performance -- Comprehensive immunomonitoring to guide the development of immunotherapeutic products for cancer -- Section 4: Strategies of passive and active immunotherapy. Adoptive T-cell therapy: engineering T-cell receptors -- Dendritic cell vaccines: sipuleucel-T and other approaches -- Antibodies to stimulate host immunity: lessons from ipilimumab -- Recombinant TRICOM-based therapeutic cancer vaccines: lessons learned -- Adjuvant strategies for vaccines: the use of adjuvants within the cancer vaccine setting -- Section 5: Improving immunotherapeutic responses. Epigenetic approaches: emerging role of histone deacetylase inhibitors in cancer immunotherapy -- Molecular profiling of immunotherapeutic resistance -- Immune stimulatory features of classical chemotherapy -- Immunotherapy and cancer therapeutics: a rich partnership -- Section 6: Targeting strategies to defeat immune suppression. JAK/STAT signaling in myeloid cells: targets for cancer immunotherapy -- Tumor-associated macrophages in cancer growth and progression -- Tumor-induced myeloid-derived suppressor cells -- HyperAcute vaccines: a novel cancer immunotherapy -- Tumor exosomes and their impact on immunity and cancer progression -- Galectins: key players in the tumor microenvironment -- IDO in immune escape: regulation and therapeutic inhibition -- IDO pathway: effect on Foxp3+ Tregs and cancer -- Arginase, nitric oxide synthase, and novel inhibitors of l-arginine metabolism in immune modulation. 
520 |a "This book highlights new principles of immune suppression that drive cancer, and offers radically new ideas about how therapy can be improved by attacking these principles. It provides an overview of immune escape as a critical trait in cancer and how applying specific combinations of immunotherapy and chemotherapy to attack this trait may radically improve the treatment of advanced disease"--Publisher's description. 
650 0 |a Cancer  |x Immunotherapy. 
650 0 |a Antineoplastic agents  |x Therapeutic use. 
650 0 |a Tumors  |x Immunological aspects. 
650 1 2 |a Neoplasms  |x therapy  |0 (DNLM)D009369Q000628 
650 2 2 |a Antineoplastic Agents  |x therapeutic use  |0 (DNLM)D000970Q000627 
650 2 2 |a Immunotherapy  |x methods  |0 (DNLM)D007167Q000379 
650 6 |a Cancer  |x Immunoth�erapie.  |0 (CaQQLa)201-0168739 
650 6 |a Anticanc�ereux  |0 (CaQQLa)201-0004692  |x Emploi en th�erapeutique.  |0 (CaQQLa)201-0373975 
650 6 |a Tumeurs  |x Immunologie.  |0 (CaQQLa)201-0049657 
650 7 |a HEALTH & FITNESS  |x Diseases  |x Cancer.  |2 bisacsh 
650 7 |a MEDICAL  |x Oncology.  |2 bisacsh 
650 7 |a Cancer  |x Immunotherapy  |2 fast  |0 (OCoLC)fst00845386 
650 7 |a Antineoplastic agents  |x Therapeutic use  |2 fast  |0 (OCoLC)fst00810609 
650 7 |a Tumors  |x Immunological aspects  |2 fast  |0 (OCoLC)fst01158775 
700 1 |a Prendergast, George C.,  |e editor. 
700 1 |a Jaffee, Elizabeth M.,  |e editor. 
776 0 8 |i Print version:  |t Cancer immunotherapy.  |b Second edition.  |d Amsterdam : Elsevier/Academic Press, [2013]  |z 9780123942968  |w (DLC) 2013444865  |w (OCoLC)864382500 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780123942968  |z Texto completo