Anorexia /
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms. Under the capable and qualified editorial le...
Clasificación: | Libro Electrónico |
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Otros Autores: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Amsterdam ; Boston :
Elsevier/AP,
2013.
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Edición: | 1st ed. |
Colección: | Vitamins and hormones ;
v. 92. |
Temas: | |
Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Front Cover; Anorexia; Copyright; Former Editors; Contents; Contributors; Preface; Chapter One: Novel Neuropeptides in the Control of Food Intake: Neuronostatin and Nesfatin-1; 1. Introduction; 1.1. Anatomic basis for the neural control of appetite; 1.2. The central melanocortin system; 1.3. The central oxytocin system; 2. Neuronostatin; 2.1. Introduction; 2.2. Neuronostatin-induced anorexia; 2.2.1. Central circuits involved in neuronostatin-induced anorexia; 2.2.2. Relationship between neuronostatin-induced anorexia and autonomic function
- 2.2.3. Physiological relevance of neuronostatin-induced anorexia3. Nesfatin-1; 3.1. Introduction; 3.2. Nesfatin-1-induced anorexia; 3.2.1. Central circuits mediating nesfatin-1-induced anorexia; 3.2.2. Peripheral nesfatin-1 in the control of food intake and metabolism; 3.2.3. Relationship between nesfatin-1-induced anorexia, autonomic activity, and fluid intake; 3.2.4. Physiological relevance of nesfatin-1 in the control of food intake and energy balance; 4. Conclusions; 4.1. The proposed central POMC-CRH-OT feeding circuit; 4.2. Oxytocinergic and nonoxytocinergic-mediated anorexia
- 3. General Aspects of Mechanisms Underlying Weight Disturbances3.1. Mitochondrial deficiencies and neurodegeneration; 3.1.1. Why is the NPY/AGRP system affected mainly in the anx/anx mouse?; 3.1.2. ATP sensitive K+ channels: Kir 6.2/SUR1; 3.1.3. Expression of Kir 6.2/SUR1 by arcuate and substantia nigra neurons; 3.2. Hypothalamic inflammation/neurodegeneration and food intake; 3.2.1. Experimental, selective ablation of hypothalamic neurons; 3.3. Hypothalamic neurogenesis and food intake; 4. Neurodegeneration and Mitochondrial Dysfunction Related to Eating Disorders in Humans
- 5. Conclusions and Future DirectionsAcknowledgments; References; Chapter Three: The Role of Ghrelin in Anorexia-Cachexia Syndromes; 1. Introduction; 2. Discovery of Ghrelin; 3. Ghrelin, GHS-R1a, and GOAT; 4. Mechanisms of Action of Ghrelin; 4.1. Ghrelin, muscle, and the GH-IGF-1 axis; 4.2. Ghrelin and appetite regulation; 4.3. Ghrelin and lipid metabolism; 4.4. Ghrelin and inflammation; 5. Ghrelin and Sarcopenia of Aging; 6. Ghrelin and Cancer Cachexia; 6.1. Safety of ghrelin and GHS in the setting of cancer; 7. Ghrelin and COPD-Induced Cachexia; 8. Ghrelin and Anorexia Nervosa