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Advances in virus research. Volume 85/
Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology.Key features: * Contributions from leading authorities * Informs and updates on all the latest developments in the field.
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam :
Academic Press,
2013.
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| Colección: | Advances in virus research ;
v. 85. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Front Cover; Advances in Virus Research; Copyright; Contents; Contributors; In Memoriam; Chapter One: Regulation of Retroviral Polyadenylation; 1. Cellular Polyadenylation; 2. Retroviral Long Terminal Repeats; 3. Retroviruses with the Poly(A) Signal Located in the U3 Region; 3.1. The negative splicing regulator promotes polyadenylation in RSV; 3.2. The Rex responsive element is required for polyadenylation in HTLV-I; 4. Retroviruses Encoding the Poly(A) Signal in the R Region; 4.1. The major splice donor is required for poly(A) site suppression at the 5LTR of HIV-1
- 4.2. Splice donor sequences are responsible for poly(A) suppression in cells and nonretroviruses4.3. MLV encodes a weak poly(A) signal; 5. Conclusions; Acknowledgments; References; Chapter Two: Open Questions About Giant Viruses; 1. Background; 1.1. Giant viruses: The latest addition to the list of double-stranded DNA viruses; 1.2. Giant viruses have a common ancestor; 2. The Traditional View: Viruses Started Small, Got Bigger; 3. Genome Reduction: A Neutral Ratchet Wheel Generating the Diversity of Large DNA Viruses; 3.1. The elusive definition of a minimal genome
- 3.2. Applying the concept of genome reduction to viruses3.3. No minimal genome for viruses; 4. Speculation on the Nature of the Giant Virus Ancestor; Acknowledgments; References; Chapter Three: Assembly and Budding of Negative-Strand RNA Viruses; 1. Introduction; 2. Virion Structure: The Final Product; 3. Steps in Assembly of Virus Budding Sites; 4. Role of Membrane Microdomains in Assembly of Envelope Glycoproteins; 5. Assembly of Viral Matrix Proteins; 6. Selection of Nucleocapsids; 7. Late Budding Functions and Virus Release; 8. Back to the Beginning: How is Assembly Initiated?
- 9. Perspectives for the FutureReferences; Chapter Four: Arthropod-Borne Flaviviruses and RNA Interference: Seeking New Approaches for Antiviral Therapy; 1. Introduction; 2. The RNA Interference Mechanism and its Antiviral Effects; 3. Arthropod-Borne Flaviviruses; 3.1. West Nile virus; 3.2. Dengue virus; 3.3. Japanese encephalitis virus and Yellow fever virus; 4. RNAi and the Mosquito Vector; 5. The Interplay Between Arthropod-Borne Flaviviruses and the Endogenous Host Cell RNAi Pathway; 6. Conclusions and Challenges; Acknowledgments; References; Index; Color Plates