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Methods in protein design. Volume 523 /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, Calif. :
Academic,
2013.
|
| Colección: | Methods in enzymology ;
volume 523. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Computational design of novel protein binders and experimental affinity maturation
- Mining tertiary structural motifs for assessment of designability
- Computational methods for controlling binding specificity
- Flexible backbone sampling methods to model and design protein alternative conformations
- Osprey: protein design with ensembles, flexibility, and provable algorithms
- Scientific benchmarks for guiding macromolecular energy function improvement
- Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins
- Multistate protein design using CLEVER and CLASSY
- Using analyses of amino acid coevolution to understand protein structure and function
- Evolution-based design of proteins
- Protein engineering and stabilization from sequence statistics: variation and covariation analysis
- Enzyme engineering by targeted libraries
- Generation of high-performance binding proteins for pepetide motifs by affinity clamping
- Engineering fibronectin-based binding proteins by yeast surface display
- Engineering and analysis of peptide-recognition domain specificities by phage display and deep sequencing
- Efficient sampling of SCHEMA chimera families to identify useful sequence elements
- Protein switch engineering by domain insertion
- Design of chimeric proteins by combination of subdomain-sized fragments
- [alpha]-helix mimicry with [alpha/beta]-peptides.