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Methods in protein design. Volume 523 /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Keating, Amy E.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, Calif. : Academic, 2013.
Colección:Methods in enzymology ; volume 523.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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245 0 0 |a Methods in protein design.  |n Volume 523 /  |c edited by Amy E. Keating. 
260 |a San Diego, Calif. :  |b Academic,  |c 2013. 
300 |a 1 online resource (xviii, 464 pages) :  |b illustrations. 
336 |a text  |b txt  |2 rdacontent 
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490 1 |a Methods in enzymology,  |x 0076-6879 ;  |v v. 523 
504 |a Includes bibliographical references and indexes. 
505 0 |a Computational design of novel protein binders and experimental affinity maturation -- Mining tertiary structural motifs for assessment of designability -- Computational methods for controlling binding specificity -- Flexible backbone sampling methods to model and design protein alternative conformations -- Osprey: protein design with ensembles, flexibility, and provable algorithms -- Scientific benchmarks for guiding macromolecular energy function improvement -- Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins -- Multistate protein design using CLEVER and CLASSY -- Using analyses of amino acid coevolution to understand protein structure and function -- Evolution-based design of proteins -- Protein engineering and stabilization from sequence statistics: variation and covariation analysis -- Enzyme engineering by targeted libraries -- Generation of high-performance binding proteins for pepetide motifs by affinity clamping -- Engineering fibronectin-based binding proteins by yeast surface display -- Engineering and analysis of peptide-recognition domain specificities by phage display and deep sequencing -- Efficient sampling of SCHEMA chimera families to identify useful sequence elements -- Protein switch engineering by domain insertion -- Design of chimeric proteins by combination of subdomain-sized fragments -- [alpha]-helix mimicry with [alpha/beta]-peptides. 
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830 0 |a Methods in enzymology ;  |v volume 523.  |x 0076-6879 
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