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G protein coupled receptors. Structure /

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as post-translation modification of GPCR in relationship to biased...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Conn, P. Michael
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, Calif. : Academic Press/Elsevier, 2013.
Colección:Methods in enzymology ; v. 520.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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245 0 0 |a G protein coupled receptors.  |p Structure /  |c edited by P. Michael Conn. 
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490 1 |a Methods in enzymology ;  |v v. 520 
504 |a Includes bibliographical references and indexes. 
505 0 |a Expression of GPCRs in Pichia pastoris for structural studies -- Conformational ensemble view of G protein-couples receptors and the effect of mutations and ligand binding -- Structural evolution of G-protein-coupled receptors: a sequence space approach -- Directed evolution of G-protein-coupled receptors for high functional expression and detergent stability -- The role of hydrophobic amino acids in the structure and function of the Rhodopsin family of G protein-coupled receptors -- Structure of [beta]-adrenergic receptors -- Advances in methods to characterize ligand-induced ionic lock and Rotamer toggle molecular switch in G protein-coupled receptors -- Crystallogenesis of adenosine A2A receptor-T4 lysozyme fusion protein: a practical route for the structure -- Probing GPCR structure: adenosine and P2Y nucleotide receptors -- Strategies for studying the ligand binding site of GPCRs: photoaffinity labeling of the VPAC1 receptor, a prototype of class B GPCRs -- Expression of mammalian G protein-coupled receptors in Caenorhabditis elegans -- Expression, purification, and structural analysis of intracellular C-termini from metabotropic glutamate receptors -- Unnatural amino acid mutagenesis of GPCRs using amber codon suppression and bioorthogonal labeling -- Mapping a ligand binding site using genetically encoded photoactivatable crosslinkers -- Alternative mRNA splicing of G protein-coupled receptors -- Functional residues essential for the activation of the C1 Cannabinoid receptor. 
588 0 |a Print version record. 
520 |a This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as post-translation modification of GPCR in relationship to biased agonism, structure-based virtual screening, and GPCR oligomerization in the brain. This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as post-translation modification of GPCR in relationship to biased agonism, structure-based virtual screening, and GPCR oligomerization in the brain. 
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655 4 |a Plates. 
700 1 |a Conn, P. Michael. 
776 0 8 |i Print version:  |a Conn, P. Michael.  |t G Protein Coupled Receptors : Structure.  |d Burlington : Elsevier Science, �2013  |z 9780123918611 
830 0 |a Methods in enzymology ;  |v v. 520. 
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