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Co-transport systems /

Current Topics in Membranes is targeted towards scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. In this volume,...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Bevensee, Mark O.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Elsevier/Academic Press, 2012.
Edición:1st ed.
Colección:Current topics in membranes ; v. 70.
Temas:
Acceso en línea:Texto completo
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Tabla de Contenidos:
  • Front Cover; Co-Transport Systems; Copyright; Dedication; Contents; Contributors; Preface; Previous Volumes in Series; Chapter One
  • Amino Acid Secondary Transporters: Toward a Common Transport Mechanism; ?1.CLASSIFICATION OF AMINO ACID TRANSPORTERS; ?2.HUMAN SLCS INVOLVED IN AMINO ACID AND NEUROTRANSMITTER TRANSPORT; ?3.THE STRUCTURAL APCS: MECHANISTIC CONCEPTS; ?4.IONS AND DIRECTIONALITY IN AMINO ACID TRANSPORT; ?5.REGULATION IN APCS FOLD TRANSPORTERS; ACKNOWLEDGMENTS; REFERENCES; Chapter Two
  • SLC5 and SLC2 Transporters in Epithelia-Cellular Role and Molecular Mechanisms; ?1.INTRODUCTION
  • ?2.PHYSIOLOGICAL SIGNIFICANCE AND MOLECULAR CHARACTERISTICS OF EPITHELIAL SUGAR TRANSPORT?3.SODIUM-GLUCOSE SYMPORT AS THE BASIS FOR ACTIVE TRANSEPITHELIAL GLUCOSE TRANSPORT; ?4.CLONING OF TRANSPORTER CDNAS, SEQUENCE HOMOLOGIES AND CONSERVED AMINO ACIDS; ?5.TRANSPORTER DOMAINS, THEIR ARRANGEMENT IN THE MEMBRANE AND THEIR FUNCTION; ?6.CRYSTAL STRUCTURES AND HOMOLOGY MODELS OF MEMBERS OF SLC5 AND SLC2; ?7.REGULATION OF TRANSPORTER ACTIVITY; ?8.SYNOPSIS; REFERENCES; Chapter Three
  • SLC4A Transporters; ?1.INTRODUCTION; ?2.SLC4A TRANSPORTERS; ?3.ION TRANSPORT PROPERTIES
  • ?4.STRUCTURE OF SLC4A TRANSPORTERS?5.INTERACTION WITH OTHER PROTEINS; ?6.CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter Four
  • The SLC10 Carrier Family: Transport Functions and Molecular Structure; ?1.INTRODUCTION; ?2.THE SLC10 FAMILY; ?3.THE LIVER BILE SALT TRANSPORTER SLC10A1 (NTCP); ?4.THE ILEAL BILE SALT TRANSPORTER ASBT (SLC10A2); ?5.NOVEL MEMBERS OF THE SLC10 FAMILY; ?6.CONCLUSION; ?ABBREVIATIONS; REFERENCES; Chapter Five
  • H+-Coupled Divalent Metal-Ion Transporter-1: Functional Properties, Physiological Roles and Therapeutics; ?1.INTRODUCTION AND HISTORY; ?2.ANIMAL MODELS
  • ?3.MUTATIONS IN HUMAN DMT1?4.FUNCTIONAL PROPERTIES OF DMT1; ?5.REGULATION OF THE CELLULAR EXPRESSION OF DMT1; ?6.TISSUE-SPECIFIC ROLES OF DMT1 IN PHYSIOLOGY AND PATHOPHYSIOLOGY; ?7.THERAPEUTICS AND NUTRITION; ACKNOWLEDGMENTS; REFERENCES; Chapter Six
  • Molecular Operation of the Cation Chloride Cotransporters: Ion Binding and Inhibitor Interaction; ?1.OVERVIEW; ?2.GENERAL STRUCTURE; ?3.ION BINDING AND INHIBITOR INTERACTION: STRUCTURE-FUNCTION STUDIES; ?4.HOMOLOGY TO HIGH RESOLUTION STRUCTURES OF BACTERIAL TRANSPORT PROTEINS; ?5.FUTURE PERSPECTIVES; ACKNOWLEDGMENTS; REFERENCES
  • Chapter Seven
  • Sodium-Sulfate/Carboxylate Cotransporters (SLC13)?1.INTRODUCTION; ?2.SLC13 GENE FAMILY; ?3.NAS COTRANSPORTERS; ?4.NAC COTRANSPORTERS; ?5.FUTURE PERSPECTIVES; ACKNOWLEDGMENTS; REFERENCES; Chapter Eight
  • Recent Advances in Structural Biology of Peptide Transporters; ?1.INTRODUCTION; ?2.FUNCTIONAL CHARACTERISTICS OF PEPT1 AND PEPT2; ?3.STRUCTURES OF PEPT1 AND PEPT2; ?4.ESSENTIAL AMINO ACID RESIDUES; ?5.FUTURE PERSPECTIVES; ACKNOWLEDGMENT; REFERENCES
  • Chapter Nine
  • The SLC16A Family of Monocarboxylate Transporters (MCTs)-Physiology and Function in Cellular Metabolism, pH Homeostasis, and Fluid Transport