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Enzyme catalysis and regulation /

Enzyme Catalysis and Regulation.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Hammes, Gordon G., 1934-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: [New York] : Academic Press, 1982.
Colección:Molecular biology
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Enzyme Catalysis and Regulation; Copyright Page; Table of Contents; Preface; Chapter 1. Protein Structure and Dynamics; References; General References on Proteins and Enzymes; Chapter 2. Probes of Enzyme Structure; Introduction; Amino Acid Sequencing; X-Ray Crystallography; Chemical Modification; Optical Spectroscopy; Nuclear Magnetic Resonance; Spin Labels; References; Chapter 3. Steady-State Enzyme Kinetics; Introduction; Single Substrate-Single Product; King-Altman Method; Inhibition of Enzyme Catalysis; Multiple Substrates; Isotope Exchange at Equilibrium
  • PH Dependence of Enzyme CatalysisTemperature Dependence of Enzyme Catalysis; Conclusion; References; Chapter 4. Transient Kinetic Methods for Studying Enzymes; Introduction; Rapid Mixing Methods; Chemical Relaxation Methods; General Solutions of Kinetic Equations; Rate Equations near Equilibrium; References; Chapter 5. Some Chemical Aspects of Enzyme Catalysis; Catalysis; Acid-Base Catalysis; Nucleophilic Catalysis; Electrophilic Catalysis; Stereochemistry; Kinetic Isotope Effects; References; Chapter 6. Elementary Steps in Enzyme Catalysis; Introduction; Binding of Substrates
  • Conformational ChangesAcid-Base Catalysis; Covalent Intermediates; Advantages of Enzymes; References; Chapter 7. Case Studies of Selected Enzyme Mechanisms; Introduction; Pancreatic Ribonuclease; Chymotrypsin; Lysozyme; Creatine Kinase; References; Chapter 8. Regulation of Enzyme Activity; Introduction; Experimental Manifestations of Regulatory Enzymes; Equilibrium Binding Isotherms; Molecular Models for Allosterism; Steady-State Kinetics; Protein Polymerization-Depolymerization; Hysteretic Enzymes; Transient Kinetics; Conclusion; References