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Genetics of stem cells. Part A /
Genetics of Stem Cells.
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Elsevier,
2012.
|
| Colección: | Progress in molecular biology and translational science ;
111. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a Genetics of stem cells. |n Part A / |c edited by Yaoliang Tang. |
| 260 | |a San Diego : |b Elsevier, |c 2012. | ||
| 300 | |a 1 online resource (xvi, 367 pages) : |b illustrations. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 0 | |a Progress in molecular biology and translational science ; |v 111 | |
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a Genetics of Stem Cells. | ||
| 505 | 0 | |a Front Cover; Genetics of Stem Cells, Part A; Copyright; Contents; Contributors; Preface; Chapter 1: Generation of Induced Pluripotent Stem Cells from Somatic Cells; I. Generation of iPSCs; II. Methods of Delivering Transcription Factors into Cells; A. Integrating Viral Vectors; B. Nonintegrating Viral Vectors; C. Nonviral Reprogramming; D. Recombinant Proteins of Transcription Factors; E. Synthetic Modified mRNA of Transcription Factors; F. microRNAs; III. Nongenetic Approaches for Reprogramming; A. Small Molecules; B. Altering Cell-Cycle Signal Pathways | |
| 505 | 8 | |a IV. Generation of Human iPSCs from Different Somatic Cell TypesV. Characterization of iPSCs; A. Genomic Integrity; B. Gene Expression Profiles; C. Epigenetic Status; D. Developmental Potential: Pluripotency; E. Differences Between iPSCs and ESCs; VI. Conclusion; References; Chapter 2: Induced Pluripotent Cells in Cardiovascular Biology: Epigenetics, Promises, and Challenges; I. Introduction; II. Non-iPS-Cell-Based Therapies and Their Limitations; A. Autologous Adult Bone-Marrow-Derived Stem Cells for Myocardial Repair; III. Therapeutic Cloning and Embryonic Stem Cells | |
| 505 | 8 | |a IV. Induced Pluripotent Stem cells from Differentiated Somatic CellsA. Generation of iPS Cells; B. Epigenetic Mechanisms of Induced Pluripotency; V. Cardiovascular Lineage Differentiation of iPS Cells; A. Applications of iPS Cells; B. Major Limitations and Challenges for Clinical Application of iPS Cells; References; Chapter 3: Reprogramming of Somatic Cells; I. Introduction; II. Reprogramming of Somatic Cells into Pluripotent Stem Cells; A. Oocyte-Dependent Nuclear Reprogramming; 1. Somatic Cell Nuclear Transfer; B. Oocyte-Independent Nuclear Reprogramming; 1. Cell Fusion | |
| 505 | 8 | |a 2. Somatic Cell Reprogramming by Transcription Factors (iPS cells)a. Methods of iPS Cell Generation; i. Viral-Integration-Based Gene Delivery System; ii. Viral-Nonintegration-Based Gene Delivery System; iii. Nonviral Vector Method of iPS Cells; iv. ESC Extract iPS Cells; v. Chemically Induced Pluripotent Stem Cells; vi. miRNA-Induced iPS Cells; 3. Cell Type and Reprogramming Efficiency; 4. Epigenetic Reprogramming Mechanism of iPS Cells; 5. Molecular Mechanism of Reprogramming; C. Incomplete Programming; D. Direct Reprogramming of Specific Lineage; 1. Immunogenicity of iPS Cells | |
| 505 | 8 | |a III. Future PerspectivesReferences; Chapter 4: Induction of Somatic Cell Reprogramming Using the MicroRNA miR-302; I. Introduction; II. Mechanism of Reprogramming; A. MicroRNA and Reprogramming; B. Mechanism of miR-302 Biogenesis; C. miR-302 Induces Global Demethylation; D. miR-302 Activates Oct4 Expression; III. Role of miR-302 in Early Embryogenesis; A. MicroRNA and Zygotic Development; B. Comparison Between SCR-Mediated Global Demethylation and Zygotic Demethylation; IV. Dual Role of miR-302: Reprogramming Effector and Tumor Suppressor; A. Pluripotency Versus Tumorigenicity: Mechanism | |
| 546 | |a English. | ||
| 650 | 0 | |a Stem cells. | |
| 650 | 0 | |a Genetics. | |
| 650 | 2 | |a Stem Cells |0 (DNLM)D013234 | |
| 650 | 2 | |a Genetics |0 (DNLM)D005823 | |
| 650 | 6 | |a Cellules souches. |0 (CaQQLa)201-0058821 | |
| 650 | 6 | |a G�en�etique. |0 (CaQQLa)201-0069234 | |
| 650 | 7 | |a genetics. |2 aat |0 (CStmoGRI)aat300138822 | |
| 650 | 7 | |a MEDICAL |x Research. |2 bisacsh | |
| 650 | 7 | |a Genetics |2 fast |0 (OCoLC)fst00940117 | |
| 650 | 7 | |a Stem cells |2 fast |0 (OCoLC)fst01132975 | |
| 700 | 1 | |a Tang, Yaoliang. | |
| 776 | 0 | 8 | |i Print version: |z 9780123984593 |
| 830 | 0 | |a Progress in molecular biology and translational science ; |v 111. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780123984593 |z Texto completo |