Cargando…
Toxicology and Human Environments /
Annotation
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston :
Elsevier/Academic Press,
2012.
|
| Edición: | First edition. |
| Colección: | Progress in molecular biology and translational science ;
v. 112. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
| LEADER | 00000cam a2200000Ii 4500 | ||
|---|---|---|---|
| 001 | SCIDIR_ocn810441755 | ||
| 003 | OCoLC | ||
| 005 | 20231117044743.0 | ||
| 006 | m o d | ||
| 007 | cr cnu---unuuu | ||
| 008 | 120918s2012 ne a ob 001 0 eng | ||
| 040 | |a AU@ |b eng |e pn |c AU@ |d OCLCO |d UIU |d E7B |d N$T |d YDXCP |d CDX |d OCLCF |d IDEBK |d S4S |d EBLCP |d UKDOC |d DEBSZ |d OCLCQ |d UAB |d OCLCQ |e rda |d MEU |d D6H |d OL$ |d UKBTH |d OCLCQ |d OCLCO |d OCLCQ |d OCLCO | ||
| 019 | |a 811760609 |a 817813493 |a 818814682 |a 823134323 |a 1039471214 |a 1102555182 |a 1112927157 | ||
| 020 | |a 9780124159082 |q (electronic bk.) | ||
| 020 | |a 0124159087 |q (electronic bk.) | ||
| 020 | |a 1283608340 | ||
| 020 | |a 9781283608343 | ||
| 020 | |z 9780124158139 | ||
| 020 | |z 0124158137 | ||
| 020 | |a 9786613920799 | ||
| 020 | |a 6613920797 | ||
| 035 | |a (OCoLC)810441755 |z (OCoLC)811760609 |z (OCoLC)817813493 |z (OCoLC)818814682 |z (OCoLC)823134323 |z (OCoLC)1039471214 |z (OCoLC)1102555182 |z (OCoLC)1112927157 | ||
| 050 | 4 | |a RA1224.3 |b .T695 2012eb | |
| 072 | 7 | |a MED |x 096000 |2 bisacsh | |
| 072 | 7 | |a MJ |2 bicssc | |
| 082 | 0 | 4 | |a 615.9 |2 23 |
| 245 | 0 | 0 | |a Toxicology and Human Environments / |c edited by Ernest Hodgson. |
| 250 | |a First edition. | ||
| 264 | 1 | |a Amsterdam ; |a Boston : |b Elsevier/Academic Press, |c 2012. | |
| 300 | |a 1 online resource (xiii, 435 pages : |b illustrations). | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Progress in molecular biology and translational science, |x 1877-1173 ; |v v. 112 | |
| 546 | |a Text in English. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 520 | 8 | |a Annotation |b Environmental toxicology is generally held to be the study of the potential of constituents of outdoor environments to impact either human health or the biological structure of the ecosystems involved. This volume is a first attempt to integrate toxicological studies of all of the many human environments, both indoor and outdoor, and their complex interrelationships. Included are considerations of natural environments, the agroecosystem, occupational, urban and domestic environments as well as the environment associated with Superfund sites and military deployments. The primary emphasis is on public health, including the potential health effects of toxicants found in different environments, the bioprocessing of such toxicants in humans and surrogate animals and the principles of risk analysis. *Approaches the toxicology of human environments in a new and unique way, stressing the complex interrelationships of all human environments and the implication for human and environmental health *Each chapter is written by an acknowledged expert and is addressed to those interested in the broader implications of the environmental modifications that are always associated with the activities of humans living and working in them. | |
| 505 | 0 | |a Front Cover; Toxicology and Human Environments; Copyright; Contents; Contributors; Preface; Chapter 1: Human Environments: Definition, Scope, and the Role of Toxicology; 1. Introduction; 1.1. Description and classification of human environments; 1.2. Natural ecosystems; 1.3. Agroecosystems; 1.4. Occupational (work) environments; 1.5. Domestic and urban environments; 1.6. Military deployment environments; 1.7. Superfund and other waste disposal sites; 1.8. Terminology; 2. Toxicant Transport Between and Within Human Environments; 3. Bioprocessing of Environmental Toxicants; 4. Interactions | |
| 505 | 8 | |a 5. Risk Assessment, Risk Management, and Risk Communication6. New Approaches to the Toxicology of Human Environments; References; Chapter 2: Estimating Human Exposure: Improving Accuracy with Chemical Markers; 1. Introduction; 2. OSHA; 3. EPA; References; Chapter 3: Metabolism of Xenobiotics of Human Environments; 1. Metabolism of Xenobiotics; 2. Metabolic Reactions; 2.1. Kinetics; 2.2. Reaction types; 3. Phase I Enzymes; 3.1. Cytochrome P450 monooxygenases; 3.2. Flavin-containing monooxygenases; 3.3. Other phase I enzymes; 3.3.1. Epoxide hydrolases; 3.3.2. Prostaglandin synthetase | |
| 505 | 8 | |a 7. Variations in Total Rate and Extent of Metabolism7.1. Physicochemical factors; 7.1.1. Electrophilicity and nucleophilicity; 7.1.2. Lipophilicity; 7.1.3. Polarity; 7.1.4. Protein binding; 7.1.5. Size; 7.1.6. Steric hindrance; 7.1.7. Esters; 7.1.8. Halogenation; 7.2. Endogenous factors; 7.2.1. Age; 7.2.2. Sex; 7.2.3. Species; 7.2.4. Pathology; 7.2.5. Genetics; 7.3. Exogenous factors; 7.3.1. Dose; 7.3.2. Nutrition; 7.3.3. Route of administration; 8. Summary; References; Chapter 4: Toxic Endpoints in the Study of Human Exposure to Environmental Chemicals; 1. Introduction to Toxic Endpoints | |
| 505 | 8 | |a 2. Toxicity Testing2.1. In vivo testing; 2.2. In vitro testing; 3. Carcinogenesis; 4. Hepatotoxicity; 5. Renal Toxicity; 6. Neurotoxicity; 6.1. Neurotoxic endpoints; 6.2. Environmental neurotoxicants; 7. Reproductive Toxicity; 8. Endocrine Toxicity; 9. Immunotoxicity: Respiratory; 9.1. The immune system and immunotoxic endpoints; 9.2. Immunotoxicants; 10. Concluding Remarks; References; Chapter 5: Pesticide Regulations: Exposure-Dose Modeling from FIFRA to FQPA; 1. Introduction; 2. FIFRA; 2.1. USDA; 2.2. USEPA; 2.3. Exposure to pesticide residues in food: tolerance assessment system | |
| 650 | 0 | |a Toxicology. | |
| 650 | 2 | |a Toxicology |0 (DNLM)D014116 | |
| 650 | 6 | |a Toxicologie. |0 (CaQQLa)201-0054329 | |
| 650 | 7 | |a toxicology. |2 aat |0 (CStmoGRI)aat300251568 | |
| 650 | 7 | |a MEDICAL |x Toxicology. |2 bisacsh | |
| 650 | 7 | |a Toxicology |2 fast |0 (OCoLC)fst01153364 | |
| 700 | 1 | |a Hodgson, Ernest, |d 1932- |e editor. | |
| 776 | 0 | 8 | |i Print version: |a Hodgson, Ernest. |t Toxicology and Human Environments. |d Burlington : Elsevier Science, �2012 |z 9780124158139 |
| 830 | 0 | |a Progress in molecular biology and translational science ; |v v. 112. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780124158139 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/18771173/112 |z Texto completo |