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Gap junctions in the brain : physiological and pathological roles /

Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Dere, Ekrem
Formato: Electrónico eBook
Idioma:Inglés
Publicado: [Place of publication not identified] : Academic Press, 2012.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Gap Junctions in the Brain: Physiological and Pathological Roles; Copyright; Contents; About the Editor; List of Contributors; Part I
  • The Physiology of Gap Junctions in the Brain; Chapter 1
  • Gap Junctions in the Brain; INTRODUCTION; STRUCTURAL ASPECTS OF GAP JUNCTIONS; TYPES OF GAP JUNCTION; CELLULAR AND BRAIN REGIONAL EXPRESSION PATTERNS OF SPECIFIC CONNEXINS; GAP JUNCTION PHARMACOLOGY; SYNCHRONIZATION AND RHYTHMIC OSCILLATION OF NEURAL ACTIVITY; GAP JUNCTION-RELATED HUMAN DISEASES; CONCLUSION; Acknowledgments; References
  • Chapter2
  • Physiology and Function of Glial Gap Junctions in the HippocampusTHE CONNEXIN GENE FAMILY; INTERCELLULAR COMMUNICATION MEDIATED BY CONNEXINS; HEMICHANNEL FUNCTIONS OF CONNEXINS; NON-CHANNEL FUNCTIONS OF CONNEXINS; EXPRESSION PATTERN OF GLIAL CONNEXINS IN THE HIPPOCAMPUS: MOLECULAR, SUBCELLULAR AND CELLULAR HETEROGENEITY; HETEROCELLULAR COUPLING AND PANGLIAL COUPLING COMPARTMENTS; FUNCTIONS OF GLIAL GAP JUNCTIONS: CONTROLLING NEUROGENESIS AND NEURONAL ACTIVITY; Acknowledgments; References; Part II
  • Gap Junctions between Astrocytes, Neurons, and Glia-Neuron Interactions
  • Chapter 3
  • Pathophysiology of Gap Junctions in the BrainINTRODUCTION; GAP JUNCTIONS: NOMENCLATURE AND GENERAL PROPERTIES; GAP JUNCTION COUPLING IN THE BRAIN; CELL-SPECIFIC EXPRESSION OF CONNEXINS IN BRAIN TISSUES; MODULATION AND REGULATION OF ELECTRICAL SYNAPSES; NEUROTRANSMITTER MODULATION AND CONNEXIN PHOSPHORYLATION; GAP JUNCTION-RELATED NEUROLOGICAL DISEASES; GAP JUNCTIONS AND BEHAVIOR; PHARMACOLOGY OF GAP JUNCTIONS; CONCLUSION; References; Chapter 4
  • Astroglial Calcium Signaling and Calcium Waves; INTRODUCTION; GLIAL CALCIUM EXCITABILITY; ASTROGLIA: HOMEOSTATIC CELLS OF THE BRAIN
  • CALCIUM SIGNALING IN ASTROCYTESASTROGLIAL CALCIUM WAVES; CONCLUSION; Acknowledgments; References; Chapter 5
  • Distribution and Function of Gap Junction Coupling in Cortical GABAergic Neurons; NEURONAL GAP JUNCTIONS AND CONNEXINS; A PREMISE ON INFERIOR OLIVE EXCITATORY NEURONS: A PRIVILEGED SITE IN THE STUDY OF NEURONAL GAP JUNCTIONS IN MAMMALS; CONNEXIN36, GAP JUNCTIONS AND ELECTRICAL COUPLING IN NEOCORTICAL GABAERGIC NEURONS; CONNEXIN36, GAP JUNCTIONS AND ELECTRICAL COUPLING IN HIPPOCAMPAL GABAERGIC INTERNEURONS
  • FUNCTIONAL PROPERTIES OF CONNEXIN36 AND CONNEXIN36-BASED GAP JUNCTIONS AND THEIR ROLE IN GABAERGIC INTERNEURONAL NETWORKSReferences; Part III
  • The Role of Gap Junctions in Brain Development; Chapter 6
  • Functions of Gap Junctions in the Developing Neocortex; INTRODUCTION; GAP JUNCTIONS, CONNEXONS, CONNEXINS AND THEIR DISTRIBUTION IN NEOCORTICAL NEURAL CELL TYPES; ROLE OF GAP JUNCTIONS IN THE VENTRICULAR ZONE AND DURING MIGRATION OF NEURONS; ROLE OF GAP JUNCTIONS IN THE SUBPLATE; GAP JUNCTIONS BETWEEN NEOCORTICAL GABAERGIC INHIBITORY INTERNEURONS