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Strategies and tactics in organic synthesis. Volume 8 /
A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, this book vividly demonstrates throug...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston :
Academic Press,
2012.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000Ia 4500 | ||
|---|---|---|---|
| 001 | SCIDIR_ocn805560582 | ||
| 003 | OCoLC | ||
| 005 | 20231117044737.0 | ||
| 006 | m o d | ||
| 007 | cr cnu---unuuu | ||
| 008 | 120809s2012 ne ob 001 0 eng d | ||
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| 019 | |a 805895359 |a 808670761 |a 1235843240 | ||
| 020 | |a 9780123865397 |q (electronic bk.) | ||
| 020 | |a 0123865395 |q (electronic bk.) | ||
| 020 | |a 9780123865403 |q (electronic bk.) | ||
| 020 | |a 0123865409 |q (electronic bk.) | ||
| 035 | |a (OCoLC)805560582 |z (OCoLC)805895359 |z (OCoLC)808670761 |z (OCoLC)1235843240 | ||
| 050 | 4 | |a QD262 |b .S77 2012 | |
| 072 | 7 | |a PNF |2 bicssc | |
| 072 | 7 | |a SCI |x 013040 |2 bisacsh | |
| 082 | 0 | 4 | |a 547/.2 |2 23 |
| 245 | 0 | 0 | |a Strategies and tactics in organic synthesis. |n Volume 8 / |c edited by M. Harmata. |
| 260 | |a Amsterdam ; |a Boston : |b Academic Press, |c 2012. | ||
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 520 | |a A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, this book vividly demonstrates through first hand accounts how synthesis is really done and how by discovering new reactions, creating new designs and building molecules with atom and step economies, the advancement of the science of organic synthesis is providing solutions through function to create a better world. Presents state-of-the-art developments in organic synthesisProvides insight and offers new perspective to problem-solvingWritten by leading experts in the field. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 500 | |a Title from publisher's Web site; (ScienceDirect, viewed on Aug. 8, 2012). | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Front Cover; Strategies and Tactics in Organic Synthesis; Copyright; Dedication; Contents; Chapter 1: Total Syntheses of Solandelactones E and F; 1. Introductions and Background; 1.1. Solandelactone and Related Natural Products; 1.2. Previous Syntheses; 1.3. Aggarwal Methodology for the Synthesis of 2-ene-1,4-diols; 2. Retrosynthetic Analysis; 3. Synthesis of Solandelactone E; 3.1. Preparation of Aldehyde 3; 3.2. Preparation of Enantioenriched Lithiated Carbamate; 3.3. Completion of Solandelactone E; 4. Synthesis of Solandelactone F; 5. Conclusions; References | |
| 505 | 8 | |a Chapter 2: The Marine Alkaloid Halichlorine: Its Defenses and Its Defeat1. Introduction; 2. The First Approach; 3. The First Surprise; 4. The Second Approach; 5. Saved by Selenium; 6. A Stereochemical Disaster-But a Blessing in Disguise; 7. The Ring A Problem and the Development of a General Annulation Method; 8. The Continuing Saga of Ring A; 9. Formation of the Macrolactone; 10. The Optical Purity Problem; 11. Conclusion; Acknowledgments; References; Chapter 3: An Adventure in Synthesis Inspired by the Pseudolaric Acids; 1. How this Chemist Came to Be; 2. Pseudolaric Acids | |
| 505 | 8 | |a 3. The First Strategy4. Development of the Copper Hydride-Induced Reductive Aldol Cyclization; 5. The Second Strategy to Pseudolaric Acid A; 6. Case 1: When Model Reactions Fail; 7. Case 2: When Model Reactions Fail; 8. Too Happy too Quickly, and the Importance of IR Spectroscopy; 9. But it was not Time to Give Up; 10. Other Natural Products; 11. Epilogue; Acknowledgments; References; Chapter 4: Total Synthesis of Papulacandin D; 1. Introduction and Background; 2. Retrosynthetic Analysis; 3. Preparation of the Spirocyclic Aryl Glycoside; 3.1. Development of Cross-Coupling Conditions | |
| 505 | 8 | |a 3.2. Optimization of Protecting Groups for the Glucal Silanol3.3. Optimization of Protecting Groups for the Aromatic Iodide; 3.4. Implementation of the Key Cross-Coupling Sequence; 3.5. Oxidative Spiroketalization and C(2)-Hydroxyl Group Protection; 3.6. Completion of the Synthesis of the Spirocyclic Aryl Glyco-Pyranoside; 4. Synthesis of Fatty Acid Side Chain 26 and Acylation; 4.1. Preparation of the Dienylaldehyde 28; 4.2. Model Study of Lewis-Base-Catalyzed Asymmetric Aldol Addition Reactions; 4.2.1. Doubly Vinylogous Aldol Addition; 4.2.2. Vinylogous Aldol Addition | |
| 650 | 0 | |a Organic compounds |x Synthesis. | |
| 650 | 6 | |a Compos�es organiques |x Synth�ese. |0 (CaQQLa)201-0020323 | |
| 650 | 7 | |a SCIENCE |x Chemistry |x Organic. |2 bisacsh | |
| 650 | 7 | |a Organic compounds |x Synthesis. |2 fast |0 (OCoLC)fst01047668 | |
| 700 | 1 | |a Harmata, Michael, |d 1959- | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780123865403 |z Texto completo |