Cargando…
Advances in clinical chemistry. Volume 58 /
Volume 58 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston :
Academic Press,
2012.
|
| Edición: | 1st ed. |
| Colección: | Advances in clinical chemistry,
v. 58 |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front cover; Advances in Clinical Chemistry; Copyright; Contents; Contributors; Preface; Chapter 1: Highly Sensitive Troponin Immunoassays: Navigating Between the Scylla and Charybdis; 1. Abstract; 2. Introduction; 3. Acute Coronary Syndrome and Myocardial Infarction; 3.1. Electrocardiography; 3.2. Biomarkers of Myocardial Necrosis; 4. Biochemistry and Biology of Troponins; 5. Clinical Significance of the Measurement of Cardiospecific Troponins; 5.1. Traditional and ``Dynamic� � Approach to Interpret Troponin Values; 5.2. Influence of Clinical and Demographical Variables on Troponin Values
- 6. ConclusionsReferences; Chapter 2: Circulating Forms of the B-Type Natriuretic Peptide Prohormone: Pathophysiologic and Clinical Considerations; 1. Abstract; 2. Background and Aim of the Study; 3. Biosynthesis of B-Type Natriuretic Peptides in Cardiomyocytes; 4. Circulating B-Type-Related Peptides: Biochemical Characteristics; 5. The Measurement of Different Circulating Forms of the B-Type-Related Natriuretic Peptides: Analytical Characteristics and Methodologic Challenges; 6. Pathophysiological Relevance of Circulating proBNP
- 7. The Need of More Specific Immunoassays for the Measurement of proBNP1-108 and BNP1-32 PeptidesReferences; Chapter 3: Next Generation Natriuretic Peptide Measurement; 1. Abstract; 2. Editorial/Current Opinion; References; Chapter 4: Cytokines in Muscle Damage; 1. Abstract; 2. Introduction; 3. Skeletal Muscle Damage-Inflammation-Regeneration: A Conspectus; 4. The Inflammatory Cell Responses to Muscle Damage; 5. The Cytokine Responses to Muscle Damage; 5.1. The Proinflammatory Cytokine Response; 5.2. The Acute-Phase Response; 5.3. The Fibrosis-Related Cytokine Response
- 5.4. The Anti-inflammatory Cytokine Response5.5. The Myokine Response; 6. The Cytokine Responses in the Assessment of Muscle Damage and Repair; 7. Conclusions; References; Chapter 5: The Immune System-A Hidden Treasure for Biomarker Discovery in Cutaneous Melanoma; Abbrevations; 1. Abstract; 2. Introduction; 3. Skin Immune System-Where the Story Begins; 3.1. Immune Surveillance at the Skin Level; 3.1.1. Cellular Components of SIS; 3.1.1.1. Adaptive Immune Surveillance; 3.1.1.2. Innate Immune Surveillance; 4. Cutaneous Melanoma Develops in a Skin Immune System Controlled Microenvironment
- 5. Immune Markers-The Road Ahead5.1. Infiltrating Immune Cells-Markers for Local Immune Response; 5.1.1. Local Response; 5.1.1.1. Tumor-Infiltrating Immune Cells-Lymphocytes, TAMs, DCs, Sustain the Local Immune Battle?; 5.1.1.2. Chemokines Receptors and Ligands; 5.1.1.3. Adhesion Molecules; 5.1.1.4. Tumor Stem Cells Are Related to Immune-Related Processes; 5.1.1.5. Immune-Related Factors� Involvement in the Metastatic Process; 5.1.1.6. Sentinel Lymph Node-The Immune Station Related to Metastasis; 5.2. Peripheral Immune Markers-Monitoring the Disease; 5.2.1. Immune Molecules