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|a 1235844124
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|a 616.07/56
|2 23
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|a Advances in clinical chemistry.
|n Volume 58 /
|c edited by Gregory S. Makowski.
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|a 1st ed.
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|a Amsterdam ;
|a Boston :
|b Academic Press,
|c 2012.
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|a 1 online resource
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|a text
|b txt
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|a computer
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|a online resource
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|a Advances in clinical chemistry,
|v v. 58
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|a Title from PDF title page (viewed on July 27, 2012).
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|a Includes bibliographical references and index.
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|a Volume 58 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology. Written by authors representing the diverse field of clinical chemistry and diagnostics, reviews in Advances in Clinical Chemistry cover a range of cutting-eduge research ranging from basic biochemical exploration to microarray technology.
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|a Front cover; Advances in Clinical Chemistry; Copyright; Contents; Contributors; Preface; Chapter 1: Highly Sensitive Troponin Immunoassays: Navigating Between the Scylla and Charybdis; 1. Abstract; 2. Introduction; 3. Acute Coronary Syndrome and Myocardial Infarction; 3.1. Electrocardiography; 3.2. Biomarkers of Myocardial Necrosis; 4. Biochemistry and Biology of Troponins; 5. Clinical Significance of the Measurement of Cardiospecific Troponins; 5.1. Traditional and ``Dynamic� � Approach to Interpret Troponin Values; 5.2. Influence of Clinical and Demographical Variables on Troponin Values
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|a 6. ConclusionsReferences; Chapter 2: Circulating Forms of the B-Type Natriuretic Peptide Prohormone: Pathophysiologic and Clinical Considerations; 1. Abstract; 2. Background and Aim of the Study; 3. Biosynthesis of B-Type Natriuretic Peptides in Cardiomyocytes; 4. Circulating B-Type-Related Peptides: Biochemical Characteristics; 5. The Measurement of Different Circulating Forms of the B-Type-Related Natriuretic Peptides: Analytical Characteristics and Methodologic Challenges; 6. Pathophysiological Relevance of Circulating proBNP
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|a 7. The Need of More Specific Immunoassays for the Measurement of proBNP1-108 and BNP1-32 PeptidesReferences; Chapter 3: Next Generation Natriuretic Peptide Measurement; 1. Abstract; 2. Editorial/Current Opinion; References; Chapter 4: Cytokines in Muscle Damage; 1. Abstract; 2. Introduction; 3. Skeletal Muscle Damage-Inflammation-Regeneration: A Conspectus; 4. The Inflammatory Cell Responses to Muscle Damage; 5. The Cytokine Responses to Muscle Damage; 5.1. The Proinflammatory Cytokine Response; 5.2. The Acute-Phase Response; 5.3. The Fibrosis-Related Cytokine Response
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|a 5.4. The Anti-inflammatory Cytokine Response5.5. The Myokine Response; 6. The Cytokine Responses in the Assessment of Muscle Damage and Repair; 7. Conclusions; References; Chapter 5: The Immune System-A Hidden Treasure for Biomarker Discovery in Cutaneous Melanoma; Abbrevations; 1. Abstract; 2. Introduction; 3. Skin Immune System-Where the Story Begins; 3.1. Immune Surveillance at the Skin Level; 3.1.1. Cellular Components of SIS; 3.1.1.1. Adaptive Immune Surveillance; 3.1.1.2. Innate Immune Surveillance; 4. Cutaneous Melanoma Develops in a Skin Immune System Controlled Microenvironment
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|a 5. Immune Markers-The Road Ahead5.1. Infiltrating Immune Cells-Markers for Local Immune Response; 5.1.1. Local Response; 5.1.1.1. Tumor-Infiltrating Immune Cells-Lymphocytes, TAMs, DCs, Sustain the Local Immune Battle?; 5.1.1.2. Chemokines Receptors and Ligands; 5.1.1.3. Adhesion Molecules; 5.1.1.4. Tumor Stem Cells Are Related to Immune-Related Processes; 5.1.1.5. Immune-Related Factors� Involvement in the Metastatic Process; 5.1.1.6. Sentinel Lymph Node-The Immune Station Related to Metastasis; 5.2. Peripheral Immune Markers-Monitoring the Disease; 5.2.1. Immune Molecules
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|a Clinical chemistry.
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|a Chemistry, Clinical
|0 (DNLM)D002624
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|a Chimie clinique.
|0 (CaQQLa)201-0016714
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|a MEDICAL
|x Clinical Medicine.
|2 bisacsh
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|a SCIENCE
|x Chemistry
|x Clinical.
|2 bisacsh
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|a Clinical chemistry
|2 fast
|0 (OCoLC)fst00864330
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|a Makowski, Gregory S.
|q (Gregory Stephen)
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|u https://sciencedirect.uam.elogim.com/science/book/9780123943835
|z Texto completo
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