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Epigenetics in human disease /
Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advance...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston :
Elsevier/Academic Press,
2012.
|
| Edición: | 1st ed. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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|---|---|---|---|
| 001 | SCIDIR_ocn796500839 | ||
| 003 | OCoLC | ||
| 005 | 20231117044731.0 | ||
| 006 | m o d | ||
| 007 | cr cnu---unuuu | ||
| 008 | 120625s2012 ne af ob 001 0 eng d | ||
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| 019 | |a 819632426 |a 823134619 | ||
| 020 | |a 9780123884152 |q (electronic bk.) | ||
| 020 | |a 0123884152 |q (electronic bk.) | ||
| 020 | |a 1283735032 | ||
| 020 | |a 9781283735032 | ||
| 020 | |z 9780123884152 |q (hbk.) | ||
| 020 | |z 0123884152 |q (hbk.) | ||
| 035 | |a (OCoLC)796500839 |z (OCoLC)819632426 |z (OCoLC)823134619 | ||
| 050 | 4 | |a RB155 |b .E65 2012 | |
| 060 | 4 | |a 2012 H-207 | |
| 060 | 4 | |a QU 475 | |
| 082 | 0 | 4 | |a 616.042 |2 23 |
| 245 | 0 | 0 | |a Epigenetics in human disease / |c edited by Trygve O. Tollefsbol. |
| 250 | |a 1st ed. | ||
| 260 | |a Amsterdam ; |a Boston : |b Elsevier/Academic Press, |c 2012. | ||
| 300 | |a 1 online resource (xiii, 577, [23] pages of plates) : |b illustrations (some color), color plates | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usageSide-by-side coverage of the basis of epigenetic diseases and their treatmentsEvaluation of recent epigenetic clinical breakthroughs. | ||
| 500 | |a Title from publisher's Web site (ScienceDirect, viewed on June 25, 2012). | ||
| 505 | 0 | |a Epigenetics of human disease / Trygve O. Tollefsbol -- Methods and strategies to determine epigenetic variation in human disease / Yoshihisa Watanabe and Masato Maekawa -- DNA methylation alterations in human cancers / Yae Kanai and Eri Arai -- Alterations of histone modifications in cancer / Ciro Mercurio, Simon Plyte and Saverio Minucci -- MicroRNA in oncogenesis / Niamh Lynam-Lennon, Steven G. Gray and Stephen G. Maher -- Epigenetic approaches to cancer therapy / Sabita N. Saldanha and Trygve O. Tollefsbol -- Epigenomics in neurobehavioral diseases / Cassandra L. Smith and Kai Huang -- Emerging role of epigenetics in human neurodevelopmental disorders / K. Naga Mohan and J. Richard Chaillet -- The epigenetics of Alzheimer's disease / Fabio Copped�e -- Epigenetic modulation of human neurobiological disorders / Takeo Kubota [and others]. | |
| 505 | 0 | |a Epigenetic basis of autoimmune disorders in humans / Biola M. Javierre, Lorenza de la Rica and Esteban Ballestar -- Approaches to autoimmune disease using epigenetic therapy / Christopher Chang -- Epigenetic mechanisms of human imprinting disorders / Richard H. Scott and Gudrun E. Moore -- Epigenetic factors in human obesity / Christopher G. Bell -- Epigenetic approaches to control obesity / Abigail S. Lapham [and others] -- Epigenetics of diabetes in humans / Charlotte Ling and Tina R�onn -- The potential of epigenetic compounds in treating diabetes / Steven G. Gray -- Epigenetic aberrations in human allergic diseases / Manori Amaraseka [and others] -- Therapy of airway disease: epigenetic potential / Peter J. Barnes -- The role of epigenetics in cardiovascular disease / Boda Zhou, Andriana Margariti and Qingbo Xu -- Epigenetics and human infectious diseases / Hans Helmut Niller and Janos Minarovits -- The epigenetics of endometriosis / Sun-Wei Guo -- Aberrant DNA methlylation in endometrial cancer / Kenta Masuda [and others] -- Stem cell epigenetics and human disease / Mehdi Shafa and Derrick E. Rancourt -- Non-coding RNA regulatory networks, epigenetics, and programming stem cell renewal and differentiation: implications for stem cell therapy / Rajesh C. Miranda -- Aging and disease: the epigenetic bridge / Andrea Fuso -- Early-life epigenetic programming of human disease and aging / Alexander M. Vaiserman. | |
| 650 | 0 | |a Medical genetics. | |
| 650 | 0 | |a Epigenetics. | |
| 650 | 0 | |a Diseases. | |
| 650 | 1 | 2 | |a Epigenomics |0 (DNLM)D057890 |
| 650 | 1 | 2 | |a Disease |0 (DNLM)D004194 |
| 650 | 2 | |a Genetics, Medical |0 (DNLM)D005826 | |
| 650 | 1 | 3 | |a epigenetics. |
| 650 | 6 | |a G�en�etique m�edicale. |0 (CaQQLa)201-0001432 | |
| 650 | 6 | |a �Epig�en�etique. |0 (CaQQLa)000270630 | |
| 650 | 6 | |a Maladies. |0 (CaQQLa)201-0078919 | |
| 650 | 7 | |a illness. |2 aat |0 (CStmoGRI)aat300189799 | |
| 650 | 7 | |a disease. |2 aat |0 (CStmoGRI)aat300055130 | |
| 650 | 7 | |a Diseases. |2 fast |0 (OCoLC)fst00895158 | |
| 650 | 7 | |a Epigenetics. |2 fast |0 (OCoLC)fst01893642 | |
| 650 | 7 | |a Medical genetics. |2 fast |0 (OCoLC)fst01014133 | |
| 655 | 4 | |a Internet Resources. | |
| 655 | 4 | |a Plates. | |
| 700 | 1 | |a Tollefsbol, Trygve O. | |
| 776 | 0 | 8 | |i Print version: |t Epigenetics in human disease. |b 1st ed. |d Amsterdam ; New York : Academic Press, 2012 |z 9780123884152 |w (OCoLC)795181568 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780123884152 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780123884152 |z Texto completo |