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The glutamate synapse as a therapeutical target : molecular organization and pathology of the glutamate synapse /
This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pat...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; New York :
Elsevier Science,
1998.
|
| Colección: | Progress in brain research ;
v. 116. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
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| 245 | 0 | 4 | |a The glutamate synapse as a therapeutical target : |b molecular organization and pathology of the glutamate synapse / |c edited by O.P. Ottersen, I.A. Langmoen, L. Gjerstad. |
| 264 | 1 | |a Amsterdam ; |a New York : |b Elsevier Science, |c 1998. | |
| 300 | |a 1 online resource (xii, 462 pages) : |b illustrations. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Progress in brain research, |x 0079-6123 ; |v volume 116 | |
| 520 | |a This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pathological conditions, and how glutamate may acquire toxic properties and lead to acute or chronic neurodegeneration. Promising targets for therapeutic strategies are discussed. A coherent picture is provided of the glutamate synapse and its molecular organization. The book therefore deals with each step in the signal process, from synthesis and vesicular uptake of glutamate to its clearance following receptor activation. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Online resource; title from publisher's Web site (ScienceDirect, viewed on June 15, 2012). | |
| 505 | 0 | |a Machine derived contents note: I. Glutamate Release and Transport. -- II. Glutamate Synthesis and Translocation to Vesicles. -- III. Glutamate Receptors. -- IV. Glutamate Toxicity and Cell Death in the Cental Nervous System. -- V. Conditions of Perturbed Glutamatergic Transmission. -- VI. Perspectives. | |
| 506 | |a Online full text access is restricted to licensed organisations. | ||
| 546 | |a English. | ||
| 650 | 0 | |a Glutamic acid |x Receptors |x Effect of drugs on. | |
| 650 | 0 | |a Epilepsy |x Molecular aspects. | |
| 650 | 0 | |a Epilepsy |x Chemotherapy. | |
| 650 | 0 | |a Glutamic acid. | |
| 650 | 0 | |a Neural transmission. | |
| 650 | 1 | 2 | |a Glutamic Acid |0 (DNLM)D018698 |
| 650 | 1 | 2 | |a Synaptic Transmission |0 (DNLM)D009435 |
| 650 | 2 | 2 | |a Receptors, Glutamate |0 (DNLM)D017470 |
| 650 | 6 | |a Acide glutamique |0 (CaQQLa)201-0032353 |x R�ecepteurs |0 (CaQQLa)201-0374874 |x Effets des m�edicaments sur. |0 (CaQQLa)201-0374874 | |
| 650 | 6 | |a �Epilepsie |0 (CaQQLa)201-0050894 |x Aspect mol�eculaire. |0 (CaQQLa)201-0374959 | |
| 650 | 6 | |a �Epilepsie |0 (CaQQLa)201-0050894 |x Chimioth�erapie. |0 (CaQQLa)201-0379519 | |
| 650 | 6 | |a Acide glutamique. |0 (CaQQLa)201-0032353 | |
| 650 | 6 | |a Transmission nerveuse. |0 (CaQQLa)201-0022975 | |
| 650 | 6 | |a R�ecepteurs du glutamate. |0 (CaQQLa)201-0315773 | |
| 650 | 7 | |a Neural transmission |2 fast |0 (OCoLC)fst01036280 | |
| 650 | 7 | |a Glutamic acid |2 fast |0 (OCoLC)fst00943728 | |
| 650 | 7 | |a Epilepsy |x Chemotherapy |2 fast |0 (OCoLC)fst00914186 | |
| 650 | 7 | |a Human Anatomy & Physiology. |2 hilcc | |
| 650 | 7 | |a Health & Biological Sciences. |2 hilcc | |
| 650 | 7 | |a Neuroscience. |2 hilcc | |
| 700 | 1 | |a Ottersen, O. P. |q (Ole P.), |e editor. | |
| 700 | 1 | |a Langmoen, Iver Arne, |e editor. | |
| 700 | 1 | |a Gjerstad, L. |q (Leif), |e editor. | |
| 773 | 0 | |t Progress in brain research |g no:116 |x 0079-6123 | |
| 776 | 0 | 8 | |i Print version: |t Glutamate synapse as a therapeutical target. |d Amsterdam ; New York : Elsevier, 1998 |z 0444827544 |w (DLC) 98029333 |w (OCoLC)39465432 |
| 830 | 0 | |a Progress in brain research ; |v v. 116. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00796123/116 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780444827548 |z Texto completo |