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The glutamate synapse as a therapeutical target : molecular organization and pathology of the glutamate synapse /
This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pat...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; New York :
Elsevier Science,
1998.
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| Colección: | Progress in brain research ;
v. 116. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
| Sumario: | This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pathological conditions, and how glutamate may acquire toxic properties and lead to acute or chronic neurodegeneration. Promising targets for therapeutic strategies are discussed. A coherent picture is provided of the glutamate synapse and its molecular organization. The book therefore deals with each step in the signal process, from synthesis and vesicular uptake of glutamate to its clearance following receptor activation. |
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| Descripción Física: | 1 online resource (xii, 462 pages) : illustrations. |
| Bibliografía: | Includes bibliographical references and index. |
| ISBN: | 0444827544 9780444827548 0080862411 9780080862415 |
| ISSN: | 0079-6123 ; 0079-6123 |
| Acceso: | Online full text access is restricted to licensed organisations. |