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Animal Models of Molecular Pathology /
This volume explores some of the most exciting recent advances in basic research on animal models of molecular pathology.
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Elsevier,
2012.
|
| Colección: | Progress in molecular biology and translational science ;
v. 105. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 001 | SCIDIR_ocn774290275 | ||
| 003 | OCoLC | ||
| 005 | 20231117044702.0 | ||
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| 019 | |a 1113790510 | ||
| 020 | |a 9780123945969 |q (electronic bk.) | ||
| 020 | |a 0123945968 |q (electronic bk.) | ||
| 020 | |a 9780123948311 |q (electronic bk.) | ||
| 020 | |a 0123948312 |q (electronic bk.) | ||
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| 035 | |a (OCoLC)774290275 |z (OCoLC)1113790510 | ||
| 050 | 4 | |a RB113 |b .A55 2012eb | |
| 072 | 7 | |a SCI |x 056000 |2 bisacsh | |
| 082 | 0 | 4 | |a 571.9/4 |2 23 |
| 245 | 0 | 0 | |a Animal Models of Molecular Pathology / |c edited by P. Michael Conn. |
| 264 | 1 | |a London : |b Elsevier, |c 2012. | |
| 300 | |a 1 online resource (xv, 454 pages, 8 unnumbered pages of plates) : |b illustrations (some color). | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Progress in molecular biology and translational science, |x 1877-1173 ; |v v. 105 | |
| 546 | |a Text in English. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a This volume explores some of the most exciting recent advances in basic research on animal models of molecular pathology. | ||
| 505 | 0 | |a Front Cover; Animal Models of Molecular Pathology; Copyright; Contents; Contributors; Preface; Animal Models of Atherosclerosis; I. Atherosclerosis Development: Basic Concepts; II. Animal Models of Atherosclerosis; A. Rabbit Models of Atherosclerosis; B. Swine Models of Atherosclerosis; C. Nonhuman Primate Models of Atherosclerosis; D. Rodent Models of Atherosclerosis; III. Concluding Remarks; Acknowledgments; References; Genetic Animal Models of Cerebral Vasculopathies; I. Cerebral Amyloid Angiopathy; A. Clinical Overview; B. Molecular Biology; C. Animal Models for CAA | |
| 505 | 8 | |a D. Insights into Pathophysiology from Transgenic ModelsII. Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL); A. Clinical Overview; B. Molecular Biology; C. Animal Models of CADASIL; a. R90C Mice; b. C428S Mice; c. R169C Mice; d. R142C Mice; e. R1031C and C455R; D. Insights into Pathophysiology from Transgenic Models; III. Concluding Remarks; Acknowledgments; References; Experimental Models of Seizures and Epilepsies; I. Introduction; II. Classification of Epileptic Seizures; A. Focal Onset Seizures; B. Generalized Onset Seizures | |
| 505 | 8 | |a C. Seizures of Unknown OriginIII. Classification of Epileptic Syndromes; IV. Models for Seizures and Epilepsies; A. The Perfect Animal Model; B. Chemical Models; C. Electrical Stimulation Models; D. Genetic Models; E. Developmental Models; F. Trauma Models; G. Emerging Epilepsy Models; V. Summary; References; Animal Models of Muscular Dystrophy; I. Dystrophin; A. Mouse Models for Duchenne Muscular Dystrophy; B. Canine Models for DMD; II. The Sarcoglycans; A. delta-Sarcoglycan and LGMD2F; B. gamma-Sarcoglycan and LGMD2C; C. beta-Sarcoglycan and LGMD2E; D. a-Sarcoglycan and LGMD2D | |
| 505 | 8 | |a E. Canine Models of Sarcoglycan DeficiencyIII. Calcium and Dystrophic Pathology; A. Calcium Contributes to the Pathology of Dystrophic Skeletal Muscles; B. Dysferlin Gene Mutations; C. Calpain 3 and LGMD2A; D. Titin and LGMD2J; IV. a-Actinin; V. Fukutin-Related Protein and Dystroglycan Processing; VI. Desmin; VII. Laminin a2; VIII. Collagen VI; IX. D4Z4 Repeats and FSHD; X. DMPK and Myotonic Dystrophy; XI. Conclusions; Acknowledgments; References; Acute Phase Proteins in Animals; I. The Acute Phase Response; A. Innate Immunity; B. Induction of the APR; C. Other Effects of the APR | |
| 505 | 8 | |a II. Acute Phase ProteinsA. C-Reactive Protein; B. Serum Amyloid A; C. Haptoglobin; D. Other APP; E. Negative Acute Phase Proteins; F. Quantitation of APP; III. Clinical Value of APP; A. Comparison to Other Markers of APR; B. Diagnosis; C. Prognosis; D. Subclinical Disease; E. Stress; F. Chronic Inflammation; IV. APP in Animals; A. Rodents and Rabbits; B. Companion Animals; C. Large Animals; D. Avian, Exotic, and Wildlife Species; V. Concluding Remarks; References; Animal Models of Hemophilia; I. The Hemophilia A Mice; A. Hemophilia A; B. The Hemophilia A Mouse Model | |
| 650 | 0 | |a Pathology, Molecular. | |
| 650 | 2 | |a Pathology, Molecular |0 (DNLM)D057089 | |
| 650 | 6 | |a Pathologie mol�eculaire. |0 (CaQQLa)201-0062220 | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Anatomy & Physiology. |2 bisacsh | |
| 650 | 7 | |a Pathology, Molecular |2 fast |0 (OCoLC)fst01054980 | |
| 700 | 1 | |a Conn, P. Michael, |e editor. | |
| 830 | 0 | |a Progress in molecular biology and translational science ; |v v. 105. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780123945969 |z Texto completo |