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Biological function of gangliosides : proceedings of Nobel Symposium 83 /

This book focuses on the role of gangliosides in three areas of medicine in which rapid progress has been made in the last decade: cancer, peripheral neuropathies and Alzheimer's disease. The volume further reflects progress in the pathogenesis of peripheral neuropathies, and the controversial...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: Nobel Symposium IBM Nordic Education Centre
Otros Autores: Svennerholm, Lars (Editor )
Formato: Electrónico Congresos, conferencias eBook
Idioma:Inglés
Publicado: Amsterdam ; New York : Elsevier, 1994.
Colección:Progress in brain research ; v. 101.
Temas:
Acceso en línea:Texto completo
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Tabla de Contenidos:
  • Front Cover; Biological Function of Gangliosides; Copyright Page; List of Contributors; Preface; Designation and schematic structure of gangliosides and allied glycosphingolipids; Contents; Chapter 1. Adhesion and counteradhesion: morphogenetic functions of the cell surface (Plenary lecture); Section I: Structure and Metabolism of Gangliosides; Chapter 2. Ganglioside metabolism: enzymology, topology and regulation; Chapter 3. Development regulation of ganglioside metabolism; Chapter 4. New mass spectral approaches to ganglioside structure determinations
  • Chapter 5. Principles of glycosphingolipid-oligosaccharide constitutionSection II: Gangliosides in Neuronal Differentiation and Development; Chapter 6. Ganglioside turnover and neural cells function: a new perspective; Chapter 7. Gangliosides as modulators of neuronal calcium; Chapter 8. Cell adhesion molecule (NCAM and N-cadherin)-dependent neurite outgrowth is modulated by gangliosides; Chapter 9. Significance of ganglioside-mediated glycosignal transduction in neuronal differentiation and development; Chapter 10. Ca2+-ganglioside-interaction in neuronal differentiation and development
  • Section III: Receptor and Cell Surface Activities of GangliosidesChapter 11. A GM1-Ganglioside-binding protein in rat brain; Chapter 12. Receptors for cholera toxin and Escherichia coli heat-labile enterotoxin revisited; Chapter 13. Carbohydrate ligands of leukocyte adhesion molecules and their therapeutic potential; Chapter 14. Receptors for gangliosides and related glycosphingolipids on central and peripheral nervous system cell membranes; Section IV: Gangliosides and Cancer; Chapter 15. Potential of genetically engineered anti-ganglioside GD2 antibodies for cancer immunotherapy
  • Chapter 16. Detection of glioma-associated gangliosides GM2, GD2, GD3, 3'-iso>LM1 and 3',6'-isoLD1 in central nervous system tumors in vitro and in vivo using epitope-defined monoclonal antibodiesChapter 17. Gangliosides associated with primary brain tumors and their expression in cell lines established from these tumors; Chapter 18. Role of gangliosides in tumor progression; Chapter 19. Tumor gangliosides as targets for active specific immunotherapy of melanoma in man; Section V: Gangliosides and Peripheral Neuropathies; Chapter 20. Gangliosides and peripheral neuropathies: an overview
  • Chapter 21. The structure of human anti-ganglioside antibodiesChapter 22. Antibodies to glycoconjugates in neuropathy and motor neuron disease; Chapter 23. Gangliosides and related glycoconjugates in myelin: relationship to peripheral neuropathies; Chapter 24. Antiglycolipid antibodies and peripheral neuropathies: links to pathogenesis; Section VI: Gangliosides and Functional Recovery of Injured Nervous System; Chapter 25. CNS Pharmacology of gangliosides