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Biological function of gangliosides : proceedings of Nobel Symposium 83 /

This book focuses on the role of gangliosides in three areas of medicine in which rapid progress has been made in the last decade: cancer, peripheral neuropathies and Alzheimer's disease. The volume further reflects progress in the pathogenesis of peripheral neuropathies, and the controversial...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: Nobel Symposium IBM Nordic Education Centre
Otros Autores: Svennerholm, Lars (Editor )
Formato: Electrónico Congresos, conferencias eBook
Idioma:Inglés
Publicado: Amsterdam ; New York : Elsevier, 1994.
Colección:Progress in brain research ; v. 101.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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111 2 |a Nobel Symposium  |d (1993 :  |c IBM Nordic Education Centre) 
245 1 0 |a Biological function of gangliosides :  |b proceedings of Nobel Symposium 83 /  |c edited by Lars Svennerholm [and six others]. 
246 3 0 |a Nobel Symposium 83 
246 3 |a Nobel Symposium eighty-three 
264 1 |a Amsterdam ;  |a New York :  |b Elsevier,  |c 1994. 
300 |a 1 online resource (xviii, 409 pages) :  |b illustrations. 
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490 1 |a Progress in brain research,  |x 0079-6123 ;  |v volume 101 
504 |a Includes bibliographical references and index. 
520 |a This book focuses on the role of gangliosides in three areas of medicine in which rapid progress has been made in the last decade: cancer, peripheral neuropathies and Alzheimer's disease. The volume further reflects progress in the pathogenesis of peripheral neuropathies, and the controversial role of gangliosides, also in therapeutic administration. There is a section on the role of gangliosides in neuronal differentiation and development and their receptor functions and cell surface activities. This excellent addition to the renowned Progress in Brain Research series also contains an invaluable plenary lecture on molecular basis of cell adhesion by Nobel prizewinner Gerald Edelman. 
588 0 |a Print version record. 
505 0 |a Front Cover; Biological Function of Gangliosides; Copyright Page; List of Contributors; Preface; Designation and schematic structure of gangliosides and allied glycosphingolipids; Contents; Chapter 1. Adhesion and counteradhesion: morphogenetic functions of the cell surface (Plenary lecture); Section I: Structure and Metabolism of Gangliosides; Chapter 2. Ganglioside metabolism: enzymology, topology and regulation; Chapter 3. Development regulation of ganglioside metabolism; Chapter 4. New mass spectral approaches to ganglioside structure determinations 
505 8 |a Chapter 5. Principles of glycosphingolipid-oligosaccharide constitutionSection II: Gangliosides in Neuronal Differentiation and Development; Chapter 6. Ganglioside turnover and neural cells function: a new perspective; Chapter 7. Gangliosides as modulators of neuronal calcium; Chapter 8. Cell adhesion molecule (NCAM and N-cadherin)-dependent neurite outgrowth is modulated by gangliosides; Chapter 9. Significance of ganglioside-mediated glycosignal transduction in neuronal differentiation and development; Chapter 10. Ca2+-ganglioside-interaction in neuronal differentiation and development 
505 8 |a Section III: Receptor and Cell Surface Activities of GangliosidesChapter 11. A GM1-Ganglioside-binding protein in rat brain; Chapter 12. Receptors for cholera toxin and Escherichia coli heat-labile enterotoxin revisited; Chapter 13. Carbohydrate ligands of leukocyte adhesion molecules and their therapeutic potential; Chapter 14. Receptors for gangliosides and related glycosphingolipids on central and peripheral nervous system cell membranes; Section IV: Gangliosides and Cancer; Chapter 15. Potential of genetically engineered anti-ganglioside GD2 antibodies for cancer immunotherapy 
505 8 |a Chapter 16. Detection of glioma-associated gangliosides GM2, GD2, GD3, 3'-iso>LM1 and 3',6'-isoLD1 in central nervous system tumors in vitro and in vivo using epitope-defined monoclonal antibodiesChapter 17. Gangliosides associated with primary brain tumors and their expression in cell lines established from these tumors; Chapter 18. Role of gangliosides in tumor progression; Chapter 19. Tumor gangliosides as targets for active specific immunotherapy of melanoma in man; Section V: Gangliosides and Peripheral Neuropathies; Chapter 20. Gangliosides and peripheral neuropathies: an overview 
505 8 |a Chapter 21. The structure of human anti-ganglioside antibodiesChapter 22. Antibodies to glycoconjugates in neuropathy and motor neuron disease; Chapter 23. Gangliosides and related glycoconjugates in myelin: relationship to peripheral neuropathies; Chapter 24. Antiglycolipid antibodies and peripheral neuropathies: links to pathogenesis; Section VI: Gangliosides and Functional Recovery of Injured Nervous System; Chapter 25. CNS Pharmacology of gangliosides 
546 |a English. 
506 |a Online access restricted to licenced organisations. 
650 0 |a Gangliosides  |x Physiological effect  |v Congresses. 
650 0 |a Neurophysiology  |v Congresses. 
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700 1 |a Svennerholm, Lars,  |e editor. 
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