Chemistry for toxicity testing /

CHAPTER 10. Methods for Generation of Test Atmospheres; BASIC PRINCIPLES; TECHNIQUES FOR GENERATION OF VAPORS; TECHNIQUES FOR GENERATION OF AEROSOLS; SUMMARY; REFERENCES; CHAPTER 11. Monitoring Vapor Concentrations in Test Atmospheres; SAMPLE COLLECTION; SAMPLE ANALYSIS; INSTRUMENT CALIBRATION; SUMM...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Jameson, C. W., Walters, Douglas B.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Boston : Butterworth Publishers, �1984.
Temas:
Toxicity testing.
Analytical chemistry.
Chemistry Techniques, Analytical > methods
Toxicology > methods
Chimie analytique.
chemical analysis.
Analytical chemistry
Toxicity testing
Tests de toxicit�e.
Chemicals > Toxic effects > Analysis
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Chemistry for Toxicity Testing; Copyright Page; Dedication; Table of Contents; THE EDITORS; THE CONTRIBUTORS; PREFACE; PART I: General Chemistry Considerations; CHAPTER 1. Analytical Chemistry Requirements for Toxicity Testing of Environmental Chemicals; PROTOCOL DEVELOPMENT; CHEMICAL PROCUREMENT; CHEMICAL ANALYSIS; CONCLUSION; REFERENCES; CHAPTER 2. Structure-Activity Prediction of the Carcinogenicity of Chemicals; RATIONALE; METHODOLOGY; PRACTICAL APPLICATIONS; FUTURE DEVELOPMENTS; SUMMARY; REFERENCES; CHAPTER 3. Problems of Testing Commercial-Grade Chemicals
  • CHEMICAL PROCUREMENTCHEMICAL ANALYSIS; PROBLEMS IN CHEMICAL ANALYSES; CONCLUSION; CHAPTER 4. Chemical/Vehicle Mixing and Analysis Problems at a Bioassay Laboratory; DOSAGE PREPARATION; PERSONNEL; SUMMARY; PART II: Dosage Mixing and Analysis; CHAPTER 5. Methods Development for Mixing Chemicals in Rodent Feed; FACTORS AFFECTING FEED BLEND HOMOGENEITY; PRELIMINARY MIXING STUDIES; HOMOGENEITY EVALUATION; EXTENDED MIXING STUDIES; DISCUSSION; CONCLUSION; CHAPTER 6. Formulations of Insoluble and Immiscible Test Agents in Liquid Vehicles for Toxicity Testing; DISCUSSION; CONCLUSION; REFERENCES
  • CHAPTER 7. Analysis of Dosed Feed SamplesGENERAL COMMENTS CONCERNING THE CHEMICAL/FEED MIX; DEVELOPMENT OF THE ANALYTICAL METHOD; STABILITY ANALYSIS; DOSAGE ANALYSIS; CONCLUSION; REFERENCE; CHAPTER 8. Stability Determinations for Chemical/Vehicle Mixtures; ROUTES OF ADMINISTRATION; CONCLUSION; PART III: Chemical Inhalation Studies; CHAPTER 9. Inhalation Toxicology: An Overview; CHAMBER DESIGN AND OPERATION; CHARACTERISTICS OF EXPERIMENTAL ATMOSPHERES; HEALTH AND SAFETY OF EMPLOYEES; MAINTENANCE OF EXPERIMENTAL ANIMALS; EXPERIMENTAL DESIGN; ASSESSMENT OF BIOLOGIC EFFECTS; QUALITY CONTROL
  • CHAPTER 13. Detection of Degradation Products in Inhalation Test Atmospheres and Analysis in Combustion Products ToxicologyDEGRADATION IN INHALATION TEST ATMOSPHERES; COMBUSTION PRODUCTS TOXICOLOGY; SUMMARY; REFERENCES; CHAPTER 14. Analytical Monitoring for Both Intentional and Unintentional Test Chemical Release during the Conduct of Inhalation Toxicity Studies; EQUIPMENT AND METHODS; RESULTS; CONCLUSION; PART IV: Chemistry Data Evaluation; CHAPTER 15. Data Evaluation and Management; MANAGEMENT CONCERNS; DECISION FLOWCHARTS; CONTROL CHARTS; SUMMARY; CONCLUSION; REFERENCES

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