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Chemistry for toxicity testing /

CHAPTER 10. Methods for Generation of Test Atmospheres; BASIC PRINCIPLES; TECHNIQUES FOR GENERATION OF VAPORS; TECHNIQUES FOR GENERATION OF AEROSOLS; SUMMARY; REFERENCES; CHAPTER 11. Monitoring Vapor Concentrations in Test Atmospheres; SAMPLE COLLECTION; SAMPLE ANALYSIS; INSTRUMENT CALIBRATION; SUMM...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Jameson, C. W., Walters, Douglas B.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Boston : Butterworth Publishers, �1984.
Temas:
Acceso en línea:Texto completo

MARC

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020 |a 9780250405473  |q (electronic bk.) 
020 |a 0250405474  |q (electronic bk.) 
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020 |a 9781483191829 
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050 4 |a RA1199 
060 4 |a QV 602  |b C517 1984 
070 |a RA1199.C48 
082 0 4 |a 615.9/07  |2 19 
245 0 0 |a Chemistry for toxicity testing /  |c edited by C.W. Jameson and Douglas B. Walters. 
260 |a Boston :  |b Butterworth Publishers,  |c �1984. 
300 |a 1 online resource (xiv, 231 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
505 0 |a Front Cover; Chemistry for Toxicity Testing; Copyright Page; Dedication; Table of Contents; THE EDITORS; THE CONTRIBUTORS; PREFACE; PART I: General Chemistry Considerations; CHAPTER 1. Analytical Chemistry Requirements for Toxicity Testing of Environmental Chemicals; PROTOCOL DEVELOPMENT; CHEMICAL PROCUREMENT; CHEMICAL ANALYSIS; CONCLUSION; REFERENCES; CHAPTER 2. Structure-Activity Prediction of the Carcinogenicity of Chemicals; RATIONALE; METHODOLOGY; PRACTICAL APPLICATIONS; FUTURE DEVELOPMENTS; SUMMARY; REFERENCES; CHAPTER 3. Problems of Testing Commercial-Grade Chemicals 
505 8 |a CHEMICAL PROCUREMENTCHEMICAL ANALYSIS; PROBLEMS IN CHEMICAL ANALYSES; CONCLUSION; CHAPTER 4. Chemical/Vehicle Mixing and Analysis Problems at a Bioassay Laboratory; DOSAGE PREPARATION; PERSONNEL; SUMMARY; PART II: Dosage Mixing and Analysis; CHAPTER 5. Methods Development for Mixing Chemicals in Rodent Feed; FACTORS AFFECTING FEED BLEND HOMOGENEITY; PRELIMINARY MIXING STUDIES; HOMOGENEITY EVALUATION; EXTENDED MIXING STUDIES; DISCUSSION; CONCLUSION; CHAPTER 6. Formulations of Insoluble and Immiscible Test Agents in Liquid Vehicles for Toxicity Testing; DISCUSSION; CONCLUSION; REFERENCES 
505 8 |a CHAPTER 7. Analysis of Dosed Feed SamplesGENERAL COMMENTS CONCERNING THE CHEMICAL/FEED MIX; DEVELOPMENT OF THE ANALYTICAL METHOD; STABILITY ANALYSIS; DOSAGE ANALYSIS; CONCLUSION; REFERENCE; CHAPTER 8. Stability Determinations for Chemical/Vehicle Mixtures; ROUTES OF ADMINISTRATION; CONCLUSION; PART III: Chemical Inhalation Studies; CHAPTER 9. Inhalation Toxicology: An Overview; CHAMBER DESIGN AND OPERATION; CHARACTERISTICS OF EXPERIMENTAL ATMOSPHERES; HEALTH AND SAFETY OF EMPLOYEES; MAINTENANCE OF EXPERIMENTAL ANIMALS; EXPERIMENTAL DESIGN; ASSESSMENT OF BIOLOGIC EFFECTS; QUALITY CONTROL 
505 8 |a CHAPTER 13. Detection of Degradation Products in Inhalation Test Atmospheres and Analysis in Combustion Products ToxicologyDEGRADATION IN INHALATION TEST ATMOSPHERES; COMBUSTION PRODUCTS TOXICOLOGY; SUMMARY; REFERENCES; CHAPTER 14. Analytical Monitoring for Both Intentional and Unintentional Test Chemical Release during the Conduct of Inhalation Toxicity Studies; EQUIPMENT AND METHODS; RESULTS; CONCLUSION; PART IV: Chemistry Data Evaluation; CHAPTER 15. Data Evaluation and Management; MANAGEMENT CONCERNS; DECISION FLOWCHARTS; CONTROL CHARTS; SUMMARY; CONCLUSION; REFERENCES 
520 |a CHAPTER 10. Methods for Generation of Test Atmospheres; BASIC PRINCIPLES; TECHNIQUES FOR GENERATION OF VAPORS; TECHNIQUES FOR GENERATION OF AEROSOLS; SUMMARY; REFERENCES; CHAPTER 11. Monitoring Vapor Concentrations in Test Atmospheres; SAMPLE COLLECTION; SAMPLE ANALYSIS; INSTRUMENT CALIBRATION; SUMMARY; REFERENCES; CHAPTER 12. Chemical Monitoring of Aerosols in Inhalation Chambers; FORWARD SCATTER DETECTORS TDA-2DN; RAM-1; BACK SCATTER DETECTOR RAM-1; CASCADE IMPACTOR OPERATION; SUMMARY; REFERENCES 
520 |a Chemistry for Toxicity Testing presents the chemical requirements for external toxicity studies. This book is organized into four parts encompassing 18 chapters that discuss the basic chemistry considerations for toxicity testing program. It also describes the structure-activity prediction of the carcinogenicity of chemicals and the development of methods for mixing chemicals in rodent feed. Some of the topics covered in the book are the formulations of insoluble and immiscible test agents in liquid medium for toxicity testing; problems of testing commercial-grade chemicals; analysis of dosed. 
546 |a English. 
650 0 |a Toxicity testing. 
650 0 |a Analytical chemistry. 
650 2 |a Chemistry Techniques, Analytical  |x methods  |0 (DNLM)D002623Q000379 
650 2 |a Toxicology  |x methods  |0 (DNLM)D014116Q000379 
650 6 |a Chimie analytique.  |0 (CaQQLa)201-0008034 
650 7 |a chemical analysis.  |2 aat  |0 (CStmoGRI)aat300081685 
650 7 |a Analytical chemistry  |2 fast  |0 (OCoLC)fst00853459 
650 7 |a Toxicity testing  |2 fast  |0 (OCoLC)fst01153336 
650 7 |a Tests de toxicit�e.  |2 ram 
653 |a Chemicals  |a Toxic effects  |a Analysis 
700 1 |a Jameson, C. W. 
700 1 |a Walters, Douglas B. 
776 0 8 |i Print version:  |t Chemistry for toxicity testing.  |d Boston : Butterworth Publishers, �1984  |w (DLC) 83019031  |w (OCoLC)9970985 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780250405473  |z Texto completo