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Molecular design and modeling. Concepts and applications. Volume 203 : Part B, Antibodies and antigens, nucleic acids, polysaccharides, and drugs /
Computer-based design and modeling, computational approaches, and instrumental methods for elucidating molecular mechanisms of protein folding and ligand-acceptor interactions are included in Volumes 202 and 203, as are genetic and chemical methods for the production of functional molecules includin...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
�1991.
|
| Colección: | Methods in enzymology ;
volume 203. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Modeling of antibody combining sites / Eduardo A. Padlan, Elvin A. Kabat
- Computer modeling of combining site structure of anti-hapten monoclonal antibodies / Michael B. Bolger, Mark A. Sherman
- Protein engineering of single-chain Fv analogs and fusion proteins / James S. Huston [and others]
- Construction of single-chain Fv derivatives of monoclonal antibodies and their production in Escherichia coli / Syd Johnson, Robert E. Bird
- Humanization of monoclonal antibodies / Detlef G�ussow, Gerhard Seemann
- Molecular modeling of antibody combining sites / Andrew C. R. Martin [and others]
- X-ray crystallographic analysis of free and antigen-complexed Fab fragments to investigate structural basis of immune recognition / Ian A. Wilson [and others]
- Predicting location of continuous epitopes in proteins from their primary structures / J. L. Pellequer [and others]
- Use of two-dimensional 1H nuclear magnetic resonance to study high-affinity antibody-peptide interactions / Janet C. Cheetham [and others]
- Nuclear magnetic resonance for studying peptide
- Antibody complexes by transferred nuclear overhauser effect difference spectroscopy / Jacob Anglister, Fred Naider
- Isotope-edited nuclear magnetic resonance studies of fab-peptide complexes / P. Tsang [and others]
- Reductive methylation and carbon-13 nuclear magnetic resonance in structure--function studies of Fc fragment and its subfragments / Joyce E. Jentoft
- Immunoelectron microscopy and image processing for epitope mapping / Nicolas Boisset, Jean N. Lamy
- Characterization of antigenic structures by mapping on resin-bound epitope analogs / Wan Syu, Jr., Lawrence Kahan
- Epitope mapping of allergens for rapid localization of continuous allergenic determinants / Bradley J. Walsh, Merlin E. Howden
- Design and production of bispecific monoclonal antibodies by hybrid hybridomas for use in immunoassay / Miyoko Takahashi [and others]
- Catalytic antibodies / Kevan M. Shokat, Peter G. Schultz
- Antibody catalysis of concerted, carbon---carbon bond-forming reactions / Donald Hilvert, Kenneth W. Hill
- Selection of T cell epitopes and vaccine engineering / Francesco Sinigaglia [and others].
- Design, construction, and characterization of poliovirus antigen chimeras / David J. Evans, Jeffrey W. Almond
- Computer simulation of DNA supercoiling / Wilma K. Olson, Peisen Zhang
- Molecular modeling to study DNA intercalation by anti-tumor drugs / Stephen Neidle, Terence C. Jenkins
- Molecular modeling in mutagenesis and carcinogenesis / Edward L. Loechler
- In Situ hybridization and immunodetection techniques for simultaneous localization of messenger RNAs and protein epitopes in tissue sections and cultured cells / Juha Peltonen [and others]
- Transfer RNA with double identity for in Vitro kinetic modeling of transfer RNA identity in Vivo / Paul Schimmel, Jonathan J. Burbaum
- Design of simplified ribonuclease P RNA by phylogenetic comparison / Norman R. Pace, David S. Waugh
- Molecular modeling and electron diffraction of polysaccharides / Serge P�erez
- Molecular design and modeling of protein--heparin interactions / Alan D. Cardin [and others]
- Computer-assisted rational drug design / Yvonne Connolly Martin
- Pattern recognition methods in rational drug design / David J. Livingstone
- Molecular electrostatic potentials for characterizing drug-biosystem interactions / Pierre-Alain Carrupt [and others]
- Pharmacophore for nicotinic agonists / T. M. Gund, C. E. Spivak
- Related chapters published in previous volumes of Methods in Enzymology.