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Molecular design and modeling. Concepts and applications. Volume 203 : Part B, Antibodies and antigens, nucleic acids, polysaccharides, and drugs /

Computer-based design and modeling, computational approaches, and instrumental methods for elucidating molecular mechanisms of protein folding and ligand-acceptor interactions are included in Volumes 202 and 203, as are genetic and chemical methods for the production of functional molecules includin...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Langone, John J. (John Joseph), 1944- (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, �1991.
Colección:Methods in enzymology ; volume 203.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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245 0 0 |a Molecular design and modeling.  |n Volume 203 :  |b Concepts and applications.  |p Part B, Antibodies and antigens, nucleic acids, polysaccharides, and drugs /  |c edited by John J. Langone. 
246 3 |a Part B, Antibodies and antigens, nucleic acids, polysaccharides, and drugs 
260 |a San Diego :  |b Academic Press,  |c �1991. 
300 |a 1 online resource (xxxi, 764 pages) :  |b illustrations (some color). 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Methods in enzymology,  |x 0076-6879 ;  |v v. 203 
500 |a Called Part B in continuation of Part A issued as volume 202 of Methods in enzymology. 
504 |a Includes bibliographical references and indexes. 
505 0 0 |t Modeling of antibody combining sites /  |r Eduardo A. Padlan, Elvin A. Kabat --  |t Computer modeling of combining site structure of anti-hapten monoclonal antibodies /  |r Michael B. Bolger, Mark A. Sherman --  |t Protein engineering of single-chain Fv analogs and fusion proteins /  |r James S. Huston [and others] --  |t Construction of single-chain Fv derivatives of monoclonal antibodies and their production in Escherichia coli /  |r Syd Johnson, Robert E. Bird --  |t Humanization of monoclonal antibodies /  |r Detlef G�ussow, Gerhard Seemann --  |t Molecular modeling of antibody combining sites /  |r Andrew C. R. Martin [and others] --  |t X-ray crystallographic analysis of free and antigen-complexed Fab fragments to investigate structural basis of immune recognition /  |r Ian A. Wilson [and others] --  |t Predicting location of continuous epitopes in proteins from their primary structures /  |r J. L. Pellequer [and others] --  |t Use of two-dimensional 1H nuclear magnetic resonance to study high-affinity antibody-peptide interactions /  |r Janet C. Cheetham [and others] --  |t Nuclear magnetic resonance for studying peptide -- Antibody complexes by transferred nuclear overhauser effect difference spectroscopy /  |r Jacob Anglister, Fred Naider --  |t Isotope-edited nuclear magnetic resonance studies of fab-peptide complexes /  |r P. Tsang [and others] --  |t Reductive methylation and carbon-13 nuclear magnetic resonance in structure--function studies of Fc fragment and its subfragments /  |r Joyce E. Jentoft --  |t Immunoelectron microscopy and image processing for epitope mapping /  |r Nicolas Boisset, Jean N. Lamy --  |t Characterization of antigenic structures by mapping on resin-bound epitope analogs /  |r Wan Syu, Jr., Lawrence Kahan --  |t Epitope mapping of allergens for rapid localization of continuous allergenic determinants /  |r Bradley J. Walsh, Merlin E. Howden --  |t Design and production of bispecific monoclonal antibodies by hybrid hybridomas for use in immunoassay /  |r Miyoko Takahashi [and others] --  |t Catalytic antibodies /  |r Kevan M. Shokat, Peter G. Schultz --  |t Antibody catalysis of concerted, carbon---carbon bond-forming reactions /  |r Donald Hilvert, Kenneth W. Hill --  |t Selection of T cell epitopes and vaccine engineering /  |r Francesco Sinigaglia [and others]. 
505 0 0 |t Design, construction, and characterization of poliovirus antigen chimeras /  |r David J. Evans, Jeffrey W. Almond --  |t Computer simulation of DNA supercoiling /  |r Wilma K. Olson, Peisen Zhang --  |t Molecular modeling to study DNA intercalation by anti-tumor drugs /  |r Stephen Neidle, Terence C. Jenkins --  |t Molecular modeling in mutagenesis and carcinogenesis /  |r Edward L. Loechler --  |t In Situ hybridization and immunodetection techniques for simultaneous localization of messenger RNAs and protein epitopes in tissue sections and cultured cells /  |r Juha Peltonen [and others] --  |t Transfer RNA with double identity for in Vitro kinetic modeling of transfer RNA identity in Vivo /  |r Paul Schimmel, Jonathan J. Burbaum --  |t Design of simplified ribonuclease P RNA by phylogenetic comparison /  |r Norman R. Pace, David S. Waugh --  |t Molecular modeling and electron diffraction of polysaccharides /  |r Serge P�erez --  |t Molecular design and modeling of protein--heparin interactions /  |r Alan D. Cardin [and others] --  |t Computer-assisted rational drug design /  |r Yvonne Connolly Martin --  |t Pattern recognition methods in rational drug design /  |r David J. Livingstone --  |t Molecular electrostatic potentials for characterizing drug-biosystem interactions /  |r Pierre-Alain Carrupt [and others] --  |t Pharmacophore for nicotinic agonists /  |r T. M. Gund, C. E. Spivak --  |t Related chapters published in previous volumes of Methods in Enzymology. 
588 0 |a Print version record. 
520 |a Computer-based design and modeling, computational approaches, and instrumental methods for elucidating molecular mechanisms of protein folding and ligand-acceptor interactions are included in Volumes 202 and 203, as are genetic and chemical methods for the production of functional molecules including antibodies and antigens, enzymes, receptors, nucleic acids and polysaccharides, and drugs. 
650 0 |a Antigen-antibody reactions. 
650 0 |a Nucleic acids. 
650 0 |a Drugs  |x Design. 
650 0 |a Molecules  |x Models. 
650 0 |a Immunoglobulins. 
650 0 |a Polysaccharides. 
650 2 |a Models, Molecular  |0 (DNLM)D008958 
650 2 |a Antibodies  |0 (DNLM)D000906 
650 2 |a Antigen-Antibody Reactions  |0 (DNLM)D000937 
650 2 |a Nucleic Acids  |0 (DNLM)D009696 
650 2 |a Polysaccharides  |0 (DNLM)D011134 
650 2 |a Drug Design  |0 (DNLM)D015195 
650 6 |a R�eaction antig�ene-anticorps.  |0 (CaQQLa)201-0006617 
650 6 |a M�edicaments  |x Conception.  |0 (CaQQLa)201-0203461 
650 6 |a Mol�ecules  |x Mod�eles.  |0 (CaQQLa)201-0015095 
650 6 |a Anticorps.  |0 (CaQQLa)201-0063080 
650 6 |a Acides nucl�eiques.  |0 (CaQQLa)201-0000254 
650 6 |a Polysaccharides.  |0 (CaQQLa)201-0011180 
650 7 |a Polysaccharides.  |2 fast  |0 (OCoLC)fst01070795 
650 7 |a Immunoglobulins.  |2 fast  |0 (OCoLC)fst00967961 
650 7 |a Antigen-antibody reactions.  |2 fast  |0 (OCoLC)fst00810520 
650 7 |a Drugs  |x Design.  |2 fast  |0 (OCoLC)fst00898790 
650 7 |a Molecules  |x Models.  |2 fast  |0 (OCoLC)fst01024878 
650 7 |a Nucleic acids.  |2 fast  |0 (OCoLC)fst01041070 
700 1 |a Langone, John J.  |q (John Joseph),  |d 1944-  |e editor. 
776 0 8 |i Print version:  |t Molecular design and modeling.  |d San Diego : Academic Press, �1991  |z 0121821048  |w (OCoLC)24787499 
830 0 |a Methods in enzymology ;  |v volume 203.  |x 0076-6879 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780121821043  |z Texto completo 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/bookseries/00766879/203  |z Texto completo