Growth factors and their receptors in cell differentiation, cancer and cancer therapy /

Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Sherbet, G. V. (Gajanan V.)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Elsevier, 2011.
Edición:1st ed.
Colección:Elsevier insights.
Temas:
Growth factors > Therapeutic use.
Cancer > Treatment.
Cellular therapy.
Cell differentiation.
Cells > Growth.
Metastasis.
Intercellular Signaling Peptides and Proteins > metabolism
Receptors, Growth Factor > metabolism
Cell Differentiation
Neoplasms > etiology
Neoplasms > therapy
Cell- and Tissue-Based Therapy
Neoplasm Metastasis
Facteurs de croissance > Emploi en th�erapeutique.
Cancer > Traitement.
Th�erapie cellulaire.
Cellules > Diff�erenciation.
Cellules > Croissance.
M�etastases.
HEALTH & FITNESS > Diseases > Cancer.
MEDICAL > Oncology.
Cancer > Treatment
Cell differentiation
Cells > Growth
Cellular therapy
Growth factors > Therapeutic use
Metastasis
Internet Resources.
Acceso en línea:Texto completo
Descripción
Sumario:Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. Humanised monoclonal antibodies raised against growth factor receptors have proved to be valuable for targeted cancer treatment and in patient management. This book reviews the latest developments providing insights into the signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for therapeutic deployment. Provides a fundamental understanding of the basic functions of growth factors and their receptors, describing how they are linked in biological processes. Aids the development of therapeutic treatments for cancer. Focuses on the interrelationships and convergence of growth factors and their receptors in development and pathogenesis and encourages greater cooperation and integration in the areas of developmental, cancer and cancer therapeutic research.
Descripción Física:1 online resource (xix, 347 pages) : illustrations.
Bibliografía:Includes bibliographical references (pages 249-347).
ISBN:9780123878205
0123878209
9786613171320
6613171328

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