Activins and inhibins /

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial l...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Litwack, Gerald
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Elsevier/AP, 2011.
Colección:Vitamins and hormones ; v. 85.
Temas:
Inhibin.
Activin.
Inhibine.
Activine.
MEDICAL > Physiology.
SCIENCE > Life Sciences > Human Anatomy & Physiology.
Activin
Inhibin
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Vitamins and Hormones: Activins and Inhibins; Copyright; Contents; Contributors; Preface; Chapter 1: Activin Receptor-Like Kinase and the Insulin Gene; I. Introduction; II. TGF-beta Family Receptors: ALK; III. Activin Isoforms A, B, and AB; IV. Nodal; V. Insulin Gene Regulation; VI. Conclusion; Acknowledgments; References; Chapter 2: Crystal Structure of Activin Receptor Type IIB Kinase Domain; I. Introduction; II. Type I Receptor Kinase Domain Structures; III. 3D Structure of ActRIIB; IV. Conclusion; References; Chapter 3: Activin/Nodal Signaling and Pluripotency
  • I. IntroductionII. Conclusion; References; Chapter 4: Intracrine Signaling Mechanisms of Activin A and TGF-beta; I. Common TGF-beta and Activin A Signaling and Target Genes: Focusing on CTGF/CCN2; II. The Early Response to Cellular Stress: Intracellular Activation of TGF-beta; III. Continuous Low-Level Activation of Activin A/TGF-beta Target Genes; IV. Intracrine Signaling: General Aspects; V. Intracrine Signaling of TGF-beta: The Stimulatory Pathway; VI. Intracrine Signaling of TGF-beta: The Inhibitory Pathway; VII. Intracrine Activin A Signaling; VIII. Conclusion; References
  • Chapter 5: Negative Regulation of Activin Signal TransductionI. Introduction; II. Extracellular Antagonists; III. Negative Regulation of Activin Receptor Function; IV. Inhibitory Smads; V. Interfering with Smad Function; VI. Negative Regulation of Gene Transcription; VII. Conclusions; Acknowledgments; References; Chapter 6: Antagonism of Activin by Activin Chimeras; I. Introduction; II. The Activin/BMP Receptor System; III. Design of Chimeras; IV. Assessment of Binding and Biological Properties of Chimeras; V. Summary, Conclusions, and Future Directions; Acknowledgments; References
  • Chapter 7: Activins and Cell MigrationI. Introduction; II. Molecular Mechanism of Activin Signaling Regulated Cell Migration; III. The Role of Activins in the Regulation of Tumor Cell Migration and Metastasis; IV. The Role of Activins in the Modulation of Immune Cell Migration; V. Conclusion and Future Prospective; Acknowledgments; References; Chapter 8: The Synthesis and Secretion of Inhibins; I. Introduction; II. Inhibin Expression and Regulation; III. Expression Profile of Inhibin in Human Tissues; IV. Inhibin Assembly; V. Circulating Inhibin Forms; VI. Concluding Remarks; References
  • Chapter 9: Multifunctional Roles of Activins in the BrainI. Introduction; II. Expression Pattern of Activin and Activin Receptor in the Brain; III. Activin Receptor and its Regulatory Proteins; IV. Functions of Activins in the CNS; V. Conclusion and Perspectives; Acknowledgments; References; Chapter 10: The Role of Activin/Nodal and Wnt Signaling in Endoderm Formation; I. Introduction; II. TGFbeta Signaling; III. WNT/beta-Catenin Signaling; IV. Applied Biology; V. Conclusions; Acknowledgments; References; Chapter 11: Activin in Glucose Metabolism; I. Introduction

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