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The unfolded protein response and cellular stress. Part C /

This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights. This volume prov...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Conn, P. Michael (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam [Netherlands] ; Boston [Mass.] : Elsevier/Academic Press, 2011.
Colección:Methods in enzymology ; v. 491.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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245 0 4 |a The unfolded protein response and cellular stress.  |n Part C /  |c edited by P. Michael Conn. 
260 |a Amsterdam [Netherlands] ;  |a Boston [Mass.] :  |b Elsevier/Academic Press,  |c 2011. 
300 |a 1 online resource (xlix, 407 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
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490 1 |a Methods in enzymology,  |x 0076-6879 ;  |v v. 491 
504 |a Includes bibliographical references and indexes. 
505 0 |a CFTR expression regulation by the unfolded protein response -- GRP78/BIP modulation of GRP78/BIP in altering sensitivity to chemotherapy -- Targeting the unfolded protein response in cancer therapy -- Large-scale analysis of UPR-mediated apoptosis in human cells -- Quantitative analysis of amino acid oxidation markers by tandem mass spectrometry -- Animal models in the study of the unfolded protein response -- Measurement of fluoride-induced endoplasmic reticulum stress using Gaussia luciferase -- Analysis of nelfinavir-induced endoplasmic reticulum stress -- Using temporal genetic switches to synchronize the unfolded protein response in cell populations in vivo -- Glycoprotein maturation and the UPR -- Monitoring and manipulating mammalian unfolded protein response -- A screen for mutants requiring activation of the unfolded protein response for viability -- Signaling pathways of proteostasis network unrevealed by proteomic approaches on the understanding of misfolded protein rescue -- Decreased secretion and unfolded protein response UP regulation -- Measuring signaling by the unfolded protein response -- Quantitative measurement of events in the mammalian unfolded protein response -- Regulation of immunoglobulin synthesis, modification, and trafficking by the unfolded protein response a quantitative approach -- Use of chemical genomics in assessment of the UPR -- Small GTPase signaling and the unfolded protein response -- Inhibitors of advanced glycation and endoplasmic reticulum stress. 
588 0 |a Print version record. 
520 |a This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights. This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights. 
650 0 |a Proteins. 
650 0 |a Protein folding. 
650 0 |a Cellular control mechanisms. 
650 0 |a Cell physiology. 
650 0 |a Stress (Physiology) 
650 0 |a Stress (Psychology) 
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650 2 |a Proteins  |0 (DNLM)D011506 
650 2 |a Stress, Physiological  |0 (DNLM)D013312 
650 2 |a Stress, Psychological  |0 (DNLM)D013315 
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650 6 |a R�egulation cellulaire.  |0 (CaQQLa)201-0005048 
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650 6 |a Stress.  |0 (CaQQLa)201-0000111 
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650 7 |a Stress (Physiology)  |2 fast  |0 (OCoLC)fst01134907 
700 1 |a Conn, P. Michael,  |e editor. 
776 0 8 |i Print version:  |t Unfolded protein response and cellular stress. Part C.  |b 1st ed.  |d San Diego, Calif. : Elsevier/Academic Press, �2011  |z 9780123859280  |w (OCoLC)704914053 
830 0 |a Methods in enzymology ;  |v v. 491. 
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