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Recent advances in Parkinson's disease /

This second volume follows on from Part I by reviewing the variety of animal models of PD current available (from drosophila to rodents to non-human primate species) and their specific contributions to PD research. This is followed by comprehensive coverage of functional neuroimaging studies that ex...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Bj�orklund, Anders, 1945-, Cenci, M. Angela
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Elsevier, 2010.
Edición:1st ed.
Colección:Progress in brain research ; v. 183, etc.
Temas:
Acceso en línea:Texto completo
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Tabla de Contenidos:
  • Cover; Recent Advances in Parkinson's Disease: Translational and Clinical Research; Copyright; List of Contributors; Preface; Contents; Section I. Animal models of PD; Chapter 1. What have we learned from Drosophila models of Parkinson's disease?; Chapter 2. Neurotoxic in vivo models of Parkinson's disease: recent advances; Chapter 3. Behavioral analysis of motor and non-motor symptoms in rodent models of Parkinson's disease; Chapter 4. Genetic mouse models of Parkinson's disease: The state of the art.
  • Chapter 5. Viral vector-mediated overexpression of a-synuclein as a progressive model ofParkinson's diseaseChapter 6. Modeling neuroinflammatory pathogenesis of Parkinson's disease; Chapter 7. The MPTP-lesioned non-human primate models of Parkinson's disease. Past, present, and future; Section II. Exploring PD with brain imaging; Chapter 8. Abnormal metabolic brain networks in Parkinson's disease: from blackboard to bedside; Chapter 9. Imaging the nigrostriatal system to monitor disease progression andtreatment-induced complications; Chapter 10. Brain imaging after neural transplantation.
  • Chapter 11. Imaging non-motor aspects of Parkinson's diseaseSection III. Frontiers in PD treatment; Chapter 12. Gene therapy for dopamine replacement; Chapter 13. Neurotrophic factor therapy for Parkinson's disease; Chapter 14. Neural grafting in Parkinson's disease: problems and possibilities; Chapter 15. Neural grafting in Parkinson's disease: unraveling the mechanisms underlyinggraft-induced dyskinesia; Chapter 16. Deep brain stimulation: state of the art and novel stimulation targets; Chapter 17. The challenge of non-motor symptoms in Parkinson's disease; Subject Index.