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Channels, carriers, and pumps : an introduction to membrane transport /
For students as well as researchers this book describes the exciting new advances in the molecular biology of transport proteins and integrates this information with transport kinetics, function, and regulation. Experimental data are linked with theory. Key Features * Provides an introduction to the...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
�1990.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Channels, Carriers, and Pumps: An Introduction to Membrane Transport; Copyright Page; Dedication; Table of Contents; Preface; List of Symbols; Chapter 1. Structural Basis of Movement across Cell Membranes; 1.1 Membrane Structure: Electron Microscopy of Biological Membranes; 1.2 Chemical Composition of Biological Membranes; 1.3 Membrane Phospholipid Structures and Their Self-Assembly; 1.4 Membrane Proteins: Their Structure and Arrangement; 1.5 Synthesis of Membrane Proteins; 1.6 Phase Transitions in Biological Membranes; 1.7 Quantitation of Membrane Dynamics
- 1.8 The Cell Membrane as a Barrier and as a PassageSuggested Readings; Chapter 2. Simple Diffusion of Nonelectrolytes and Ions; 2.1 Diffusion as a Random Walk; 2.2 The Electrical Force Acting on an Ion; 2.3 Permeability Coefficients and Partition Coefficients; 2.4 Measurement of Permeability Coefficients; 2.5 Analysis of Permeability Data; 2.6 The Membrane as a Hydrophobic Sieve; 2.7 Osmosis and the Diffusion of Water; 2.8 Definition of Reflection Coefficient; 2.9 Comparison of Osmotic and Diffusive Flow of Water Suggested Readings; Suggested Readings
- Chapter 3. Ion Channels across Cell Membranes3.1 The Gramicidin Channel; 3.2 The End-Plate (Acetycholine Receptor) Channel; 3.3 Conductances and Cross-Sectional Areas of Single Channels; 3.4 An Experimental Interlude; 3.5 Diffusion Potentials: Goldman-Hodgkin-Katz Equation; 3.6 Regulation and Modulation of Channel Opening; 3.7 Donnan Potentials and Donnan Distribution; 3.8 Osmotic Consequences of Fixed Anions within the Cell; Suggested Readings; Chapter 4. Carrier-Mediated Transport: Facilitated Diffusion; 4.1 Inhibition of Mediated Transport Systems; 4.2 Kinetics of Carrier Transport
- 4.3 The Carrier Model4.4 Valinomycin: An Artificial Membrane Carrier That Works by a Solubility-Diffusion Mechanism; 4.5 Two Conformations of the Carrier; 4.6 A Deeper Analysis of the Kinetics of CarrierTransport; 4.7 Electrogenic Aspects of Carrier Transport; 4.8 Some Individual Transport Systems; 4.9 An Overall View of the Membrane Carriers: Carriersand Channels Compared; 4.10 The Full Equation for Carrier Transport; Suggested Readings; Chapter 5. Coupling of Flows of Substrates: Antiporters and Symporters; 5.1 Countertransport on the Simple Carrier
- 5.2 Exchange-Only Systems: The Antiporters5.3 The Cotransport Systems: Two (or More) Substrates That Ride Together in Symport on a Simple Carrier; Suggested Readings; Chapter 6. Primary Active Transport Systems; 6.1 The Sodium Pump of the Plasma Membrane; 6.2 The Calcium Pump of Sarcoplasmic Reticulum; 6.3 The Calcium Pump of the Plasma Membrane; 6.4 The H +, K+-ATPase of Gastric Mucosa: The Proton Pump of the Stomach; 6.5 The E1E2 ATPases Compared; 6.6 The F0 F1, ATPases; 6.7 The Vacuolar Proton-Activated ATPase; 6.8 An ATP-Driven Anion Pump