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Medicinal chemistry advances : proceedings of the Seventh International Symposium on Medicinal Chemistry, Torremolinos, Spain, 2-5 September 1980 /

Medicinal Chemistry Advances covers the proceedings of the Seventh International Symposium on Medicinal Chemistry. The book reviews the papers presented in the symposium. The main topics that this book covers are nucleosides in chemotherapy; theoretical approaches to medicinal chemistry; platelets a...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: International Symposium on Medicinal Chemistry Torremolinos, Spain
Otros Autores: Heras, Federico G. de las, Vega, Salvador
Formato: Electrónico Congresos, conferencias eBook
Idioma:Inglés
Publicado: Oxford ; New York : Pergamon Press, 1981.
Edición:1st ed.
Temas:
Acceso en línea:Texto completo

MARC

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111 2 |a International Symposium on Medicinal Chemistry  |n (7th :  |d 1980 :  |c Torremolinos, Spain) 
245 1 0 |a Medicinal chemistry advances :  |b proceedings of the Seventh International Symposium on Medicinal Chemistry, Torremolinos, Spain, 2-5 September 1980 /  |c edited by Federico G. de las Heras and Salvador Vega. 
250 |a 1st ed. 
260 |a Oxford ;  |a New York :  |b Pergamon Press,  |c 1981. 
300 |a 1 online resource (xiii, 512 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
506 |3 Use copy  |f Restrictions unspecified  |2 star  |5 MiAaHDL 
533 |a Electronic reproduction.  |b [Place of publication not identified] :  |c HathiTrust Digital Library,  |d 2010.  |5 MiAaHDL 
538 |a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.  |u http://purl.oclc.org/DLF/benchrepro0212  |5 MiAaHDL 
583 1 |a digitized  |c 2010  |h HathiTrust Digital Library  |l committed to preserve  |2 pda  |5 MiAaHDL 
588 0 |a Print version record. 
505 0 |a Front Cover; Medicinal Chemistry Advances; Copyright Page; Contents; List of Contributors; Introduction; Chapter 1. Current Options in Drug Design; ABSTRACT; KEYWORDS; INTRODUCTION; THE DISCOVERY OF ""LEAD"" COMPOUNDS; DRUGS AT RECEPTOR SITES; MOLECULAR MODIFICATION; REFERENCES; Chapter 2. Medicinal Chemistry and Current Problems in Drug Development; ABSTRACT; KEY WORDS; INTRODUCTION; ACKNOWLEDGMENT; Chapter 3. 2'-Fluoro-arabinosyl Pyrimidine Nucleosides: Chemistry, Antiviral, and Potential Anticancer Activities; ABSTRACT; KEYWORDS; REFERENCES 
505 8 |a Chapter 4. Nucleoside Antibiotics. Mode of ActionABSTRACT; KEYWORDS; INTRODUCTION; INHIBITORS OF NUCLEIC ACID SYNTHESIS; INHIBITORS OF PROTEIN SYNTHESIS; REFERENCES; Chapter 5. Antitumor and Antiviral Activity of N6-Hydroxyadenine Nucleosides and Related Derivatives; ABSTRACT; KEYWORDS; INTRODUCTION; RIBOSYL NUCLEOSIDES; ARABINOSYL DERIVATIVES; 2-SUBSTITUTED PURINE NUCLEOSIDES; DISCUSSION AND CONCLUSIONS; ACKNOWLEDGEMENTS; REFERENCES; Chapter 6. Alkylating Nucleosides; ABSTRACT; KEYWORDS; INTRODUCTION; CHEMISTRY; CYTOSTATIC ACTIVITY; MODE OF ACTION; ACKNOWLEDGMENTS; REFERENCES 
505 8 |a Chapter 7. Molecular Engineering: A General Approach to QSARABSTRACT; KEYWORDS; INTRODUCTION; MOLECULAR SPACES; PARAMETERS; MOLECULAR ENGINEERING; METHODOLOGICAL TOOLS; PATTERN RECOGNITION; THE FUTURE OF QSAR; REFERENCES; Chapter 8. Towards More Realistic Computer Simulations in Theoretical Molecular Biology; Electrostatic Potential Maps Versus Iso-energy Maps; Characterization of an Atom in a Molecule; Basis Set Superposition Error; Direct Computations of the Correlation Energy Correction; Indirect Computations of the Inter-molecular Correlation Energy Correction; Induction Energy Correction 
505 8 |a Static Reaction FieldTemperature Induced Degeneracy; Entropy and Free Energy Computations; Time Dependent Simulations; REFERENCES; Chapter 9. AB Initio Quantum Chemical Approach to the Antibiotic Activity of �-Lactams; ABSTRACT; KEYWORDS; INTRODUCTION; PROCEDURE; REACTION SURFACES; ANALYSIS OF THE MOLECULAR ORBITALS AND ATOMIC CHARGES; CONCLUSIONS; ACKNOWLEDGEMENTS; REFERENCES; Chapter 10. Cyclic Analogues of Agonists as a Tool for Structure-Activity Relationships; ABSTRACT; KEYWORDS; INTRODUCTION; METHODS OF CONTROLLING MOLECULAR GEOMETRY; CYCLIC ACETYLCHOLINE ANALOGUES 
505 8 |a CYCLIC FENTANYL ANALOGUESCYCLIC SEROTONIN ANALOGUES; ACKNOWLEDGEMENT; REFERENCES; Chapter 11. Thromboxane A2 and Atherosclerosis; ABSTRACT; KEYWORDS; INTRODUCTION; VASCULAR INJURY AND ATHEROGENICITY; ENDOTHELIOPATHY; THROMBOXANE A2 IN VASCULAR INJURY; THROMBOXANE A2 IN THROMBUS FORMATION; PLASMA THROMBOXANE B2 LEVELS; PHTHALAZINOL; CONCLUDING REMARKS; ACKNOWLEDGEMENT; REFERENCES; Chapter 12. Biological Activities of Some Metabolites and Analogues of Prostacyclin; ABSTRACT; KEYWORDS; INTRODUCTION; ACTIVITY OF PROSTACYCLIN METABOLITES; ACTIVITY OF STABLE PROSTACYCLIN ANALOGUES; REFERENCES 
520 |a Medicinal Chemistry Advances covers the proceedings of the Seventh International Symposium on Medicinal Chemistry. The book reviews the papers presented in the symposium. The main topics that this book covers are nucleosides in chemotherapy; theoretical approaches to medicinal chemistry; platelets and antithrombotic agents; receptors; antiviral agents; antilipidemic agents; respiratory system; central nervous system; enzyme inhibitors; and bioactive peptides. Chemists, pharmacologists, biochemists, physicians and other professionals and researchers concerned with the development of pharmaceuti. 
650 0 |a Pharmaceutical chemistry  |v Congresses. 
650 0 |a Pharmaceutical chemistry. 
650 2 |a Chemistry, Pharmaceutical  |0 (DNLM)D002626 
650 6 |a Chimie pharmaceutique  |0 (CaQQLa)201-0028674  |v Congr�es.  |0 (CaQQLa)201-0378219 
650 6 |a Chimie pharmaceutique.  |0 (CaQQLa)201-0028674 
650 7 |a Pharmaceutical chemistry.  |2 fast  |0 (OCoLC)fst01060115 
650 1 7 |a Medische chemie.  |2 gtt 
650 1 7 |a Farmacochemie.  |2 gtt 
650 1 7 |a Geneesmiddelen.  |2 gtt 
655 2 |a Congress  |0 (DNLM)D016423 
655 7 |a Conference papers and proceedings.  |2 fast  |0 (OCoLC)fst01423772 
655 7 |a Conference papers and proceedings.  |2 lcgft 
655 7 |a Actes de congr�es.  |2 rvmgf  |0 (CaQQLa)RVMGF-000001049 
700 1 |a Heras, Federico G. de las. 
700 1 |a Vega, Salvador. 
776 0 8 |i Print version:  |a International Symposium on Medicinal Chemistry (7th : 1980 : Torremolinos, Spain).  |t Medicinal chemistry advances.  |b 1st ed.  |d Oxford ; New York : Pergamon Press, 1981  |w (DLC) 81197395  |w (OCoLC)8098076 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780080252971  |z Texto completo